Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153458173> ?p ?o ?g. }
- W2153458173 endingPage "6400" @default.
- W2153458173 startingPage "6394" @default.
- W2153458173 abstract "It has been proposed that schizophrenia results, in part, from the inappropriate or spurious attribution of salience to cues in the environment. We have recently reported neural correlates of salience in the basolateral amygdala (ABL) of rats during learning in an odor-guided discrimination task. Here we tested whether this dopamine-dependent salience signal is altered in rats with neonatal ventral hippocampal lesions (NVHLs), a rodent model of schizophrenia. We found that ABL signals related to violations in reward prediction were only mildly affected by NVHL; however, neurons in rats with NVHLs showed significantly stronger selectivity during odor sampling, particularly for the more salient large-reward cue. The elevated cue-evoked activity in NVHL rats was correlated with heightened orienting behavior and also with changes in firing to the shifts in reward, suggesting that it reflected abnormal signaling of the large reward-predicting cue's salience. These results are broadly consistent with the proposal that schizophrenics suffer from enhanced signaling of salience." @default.
- W2153458173 created "2016-06-24" @default.
- W2153458173 creator A5021135343 @default.
- W2153458173 creator A5030822295 @default.
- W2153458173 creator A5067979006 @default.
- W2153458173 creator A5073852628 @default.
- W2153458173 creator A5080695283 @default.
- W2153458173 date "2015-04-22" @default.
- W2153458173 modified "2023-10-16" @default.
- W2153458173 title "Altered Basolateral Amygdala Encoding in an Animal Model of Schizophrenia" @default.
- W2153458173 cites W1482139424 @default.
- W2153458173 cites W1537623475 @default.
- W2153458173 cites W1595744040 @default.
- W2153458173 cites W1639906621 @default.
- W2153458173 cites W1825807651 @default.
- W2153458173 cites W1943533902 @default.
- W2153458173 cites W1948130162 @default.
- W2153458173 cites W1964043050 @default.
- W2153458173 cites W1965655488 @default.
- W2153458173 cites W1966465143 @default.
- W2153458173 cites W1968700646 @default.
- W2153458173 cites W1977113781 @default.
- W2153458173 cites W1977524784 @default.
- W2153458173 cites W1982122163 @default.
- W2153458173 cites W1983230739 @default.
- W2153458173 cites W1984500243 @default.
- W2153458173 cites W1985682061 @default.
- W2153458173 cites W1986132098 @default.
- W2153458173 cites W1999333694 @default.
- W2153458173 cites W2002819260 @default.
- W2153458173 cites W2004497754 @default.
- W2153458173 cites W2008537040 @default.
- W2153458173 cites W2011521010 @default.
- W2153458173 cites W2012955582 @default.
- W2153458173 cites W2013952470 @default.
- W2153458173 cites W2024277205 @default.
- W2153458173 cites W2024910015 @default.
- W2153458173 cites W2035803106 @default.
- W2153458173 cites W2037877714 @default.
- W2153458173 cites W2038021984 @default.
- W2153458173 cites W2061902128 @default.
- W2153458173 cites W2065864722 @default.
- W2153458173 cites W2071090720 @default.
- W2153458173 cites W2071187916 @default.
- W2153458173 cites W2074937887 @default.
- W2153458173 cites W2080039748 @default.
- W2153458173 cites W2081620069 @default.
- W2153458173 cites W2084062303 @default.
- W2153458173 cites W2089912569 @default.
- W2153458173 cites W2090144013 @default.
- W2153458173 cites W2094340322 @default.
- W2153458173 cites W2098205950 @default.
- W2153458173 cites W2099935324 @default.
- W2153458173 cites W2101384549 @default.
- W2153458173 cites W2112569537 @default.
- W2153458173 cites W2128508619 @default.
- W2153458173 cites W2133622401 @default.
- W2153458173 cites W2135861595 @default.
- W2153458173 cites W2136925527 @default.
- W2153458173 cites W2139358036 @default.
- W2153458173 cites W2146665093 @default.
- W2153458173 cites W2154169426 @default.
- W2153458173 cites W2160695817 @default.
- W2153458173 cites W2163512761 @default.
- W2153458173 cites W2167821068 @default.
- W2153458173 cites W2320983896 @default.
- W2153458173 cites W4230783006 @default.
- W2153458173 doi "https://doi.org/10.1523/jneurosci.5096-14.2015" @default.
- W2153458173 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4405556" @default.
- W2153458173 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25904791" @default.
- W2153458173 hasPublicationYear "2015" @default.
- W2153458173 type Work @default.
- W2153458173 sameAs 2153458173 @default.
- W2153458173 citedByCount "9" @default.
- W2153458173 countsByYear W21534581732015 @default.
- W2153458173 countsByYear W21534581732016 @default.
- W2153458173 countsByYear W21534581732017 @default.
- W2153458173 countsByYear W21534581732020 @default.
- W2153458173 countsByYear W21534581732021 @default.
- W2153458173 countsByYear W21534581732023 @default.
- W2153458173 crossrefType "journal-article" @default.
- W2153458173 hasAuthorship W2153458173A5021135343 @default.
- W2153458173 hasAuthorship W2153458173A5030822295 @default.
- W2153458173 hasAuthorship W2153458173A5067979006 @default.
- W2153458173 hasAuthorship W2153458173A5073852628 @default.
- W2153458173 hasAuthorship W2153458173A5080695283 @default.
- W2153458173 hasBestOaLocation W21534581731 @default.
- W2153458173 hasConcept C108154423 @default.
- W2153458173 hasConcept C148762608 @default.
- W2153458173 hasConcept C15744967 @default.
- W2153458173 hasConcept C169760540 @default.
- W2153458173 hasConcept C180747234 @default.
- W2153458173 hasConcept C2778916471 @default.
- W2153458173 hasConcept C2779144063 @default.
- W2153458173 hasConcept C2780451725 @default.
- W2153458173 hasConceptScore W2153458173C108154423 @default.
- W2153458173 hasConceptScore W2153458173C148762608 @default.
- W2153458173 hasConceptScore W2153458173C15744967 @default.