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- W2153500954 abstract "Summary When performing association studies in populations that have not been the focus of large‐scale investigations of haplotype variation, it is often helpful to rely on genomic databases in other populations for study design and analysis – such as in the selection of tag SNPs and in the imputation of missing genotypes. One way of improving the use of these databases is to rely on a mixture of database samples that is similar to the population of interest, rather than using the single most similar database sample. We demonstrate the effectiveness of the mixture approach in the application of African, European, and East Asian HapMap samples for tag SNP selection in populations from India, a genetically intermediate region underrepresented in genomic studies of haplotype variation." @default.
- W2153500954 created "2016-06-24" @default.
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- W2153500954 date "2008-05-30" @default.
- W2153500954 modified "2023-10-02" @default.
- W2153500954 title "Using Population Mixtures to Optimize the Utility of Genomic Databases: Linkage Disequilibrium and Association Study Design in India" @default.
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- W2153500954 doi "https://doi.org/10.1111/j.1469-1809.2008.00457.x" @default.
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