Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153627130> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2153627130 abstract "Endocrine tumours, with digestive localization, are tumours with variable forecast which are independent of their invasive and metastatic extensions. The experimental model of endocrine tumors with liver dissemination is available for evaluation of new medical therapeutics such as antiangiogenic therapy. MRI is a non invasive modality allowing in vivo examinations and is suitable to follow liver lesion evolution during longitudinal study on animal models. The goal of this study was to assess the detection level and to characterize the liver lesions in an athymic nude mouse model, using a dedicated MRI protocol and an optimized synchronization strategy at high magnetic field strength. The experiments were performed at 7T. To detect liver lesions, respiratory-triggered T2-weighted MR images is the sequence of choice. With conventional acquisition strategies used on small animal MR systems, trigger signal is performed at each respiratory cycle and thus, the T2 contrast is not freely controlled. Additionally, the slice number is limited by the expiration delay. To overcome these drawbacks, we proposed an original strategy enabling true T2-weighted imaging with minimal movement artifacts, regardless of the respiratory period and the number of slices. This protocol was used to carry out a longitudinal follow-up of hepatic lesions in 8 nude mice at stages D7, D12, D17 and D24. The fraction of lesion over the total liver volume was quantified. Moreover, the characterization of cystic or non-cystic type of lesions was achieved using various TE leading to T2 maps. In conclusion, the level of lesion detection and characterization of liver lesions was performed using a devoted protocol with original synchronization strategy dedicated to high field MRI. MR imaging could be used with relevance in the evaluation of new therapeutics protocol for treatment of liver lesions in neuroendocrine tumors using small animal model." @default.
- W2153627130 created "2016-06-24" @default.
- W2153627130 creator A5015300478 @default.
- W2153627130 creator A5036116274 @default.
- W2153627130 creator A5042575799 @default.
- W2153627130 creator A5042734712 @default.
- W2153627130 creator A5045608412 @default.
- W2153627130 creator A5046551225 @default.
- W2153627130 creator A5063925001 @default.
- W2153627130 date "2007-08-01" @default.
- W2153627130 modified "2023-10-17" @default.
- W2153627130 title "Characterization of neuro-endocrine tumors in an athymic nude mouse model using dedicated synchronization strategies for T2-weigted MR imaging at 7T" @default.
- W2153627130 cites W1965668135 @default.
- W2153627130 cites W1970299228 @default.
- W2153627130 cites W197597788 @default.
- W2153627130 cites W2006142456 @default.
- W2153627130 cites W2016826226 @default.
- W2153627130 cites W2022318297 @default.
- W2153627130 cites W2075792516 @default.
- W2153627130 cites W2167577015 @default.
- W2153627130 doi "https://doi.org/10.1109/iembs.2007.4352930" @default.
- W2153627130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18002596" @default.
- W2153627130 hasPublicationYear "2007" @default.
- W2153627130 type Work @default.
- W2153627130 sameAs 2153627130 @default.
- W2153627130 citedByCount "2" @default.
- W2153627130 countsByYear W21536271302020 @default.
- W2153627130 crossrefType "proceedings-article" @default.
- W2153627130 hasAuthorship W2153627130A5015300478 @default.
- W2153627130 hasAuthorship W2153627130A5036116274 @default.
- W2153627130 hasAuthorship W2153627130A5042575799 @default.
- W2153627130 hasAuthorship W2153627130A5042734712 @default.
- W2153627130 hasAuthorship W2153627130A5045608412 @default.
- W2153627130 hasAuthorship W2153627130A5046551225 @default.
- W2153627130 hasAuthorship W2153627130A5063925001 @default.
- W2153627130 hasConcept C126322002 @default.
- W2153627130 hasConcept C126838900 @default.
- W2153627130 hasConcept C142724271 @default.
- W2153627130 hasConcept C143409427 @default.
- W2153627130 hasConcept C150903083 @default.
- W2153627130 hasConcept C207001950 @default.
- W2153627130 hasConcept C2781156865 @default.
- W2153627130 hasConcept C2989005 @default.
- W2153627130 hasConcept C46699223 @default.
- W2153627130 hasConcept C534529494 @default.
- W2153627130 hasConcept C71315377 @default.
- W2153627130 hasConcept C71924100 @default.
- W2153627130 hasConcept C86803240 @default.
- W2153627130 hasConceptScore W2153627130C126322002 @default.
- W2153627130 hasConceptScore W2153627130C126838900 @default.
- W2153627130 hasConceptScore W2153627130C142724271 @default.
- W2153627130 hasConceptScore W2153627130C143409427 @default.
- W2153627130 hasConceptScore W2153627130C150903083 @default.
- W2153627130 hasConceptScore W2153627130C207001950 @default.
- W2153627130 hasConceptScore W2153627130C2781156865 @default.
- W2153627130 hasConceptScore W2153627130C2989005 @default.
- W2153627130 hasConceptScore W2153627130C46699223 @default.
- W2153627130 hasConceptScore W2153627130C534529494 @default.
- W2153627130 hasConceptScore W2153627130C71315377 @default.
- W2153627130 hasConceptScore W2153627130C71924100 @default.
- W2153627130 hasConceptScore W2153627130C86803240 @default.
- W2153627130 hasLocation W21536271301 @default.
- W2153627130 hasLocation W21536271302 @default.
- W2153627130 hasOpenAccess W2153627130 @default.
- W2153627130 hasPrimaryLocation W21536271301 @default.
- W2153627130 hasRelatedWork W141524600 @default.
- W2153627130 hasRelatedWork W1523452257 @default.
- W2153627130 hasRelatedWork W1841185769 @default.
- W2153627130 hasRelatedWork W2152093795 @default.
- W2153627130 hasRelatedWork W2155887765 @default.
- W2153627130 hasRelatedWork W2162597084 @default.
- W2153627130 hasRelatedWork W2388452377 @default.
- W2153627130 hasRelatedWork W2400727047 @default.
- W2153627130 hasRelatedWork W2402119494 @default.
- W2153627130 hasRelatedWork W1929462032 @default.
- W2153627130 isParatext "false" @default.
- W2153627130 isRetracted "false" @default.
- W2153627130 magId "2153627130" @default.
- W2153627130 workType "article" @default.