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- W2153767402 abstract "Polymyositis (PM) and dermatomyositis (DM) are systemic inflammatory disorders affecting skeletal muscles and other organs, especially the digestive tract.1-8 Oesophageal motor disturbances are common, occurring in as many as 25–60% of patients with PM/DM.5 Gastrointestinal disease is less recognised in PM/DM, though it may be responsible for life threatening complications—for example, dramatic haemorrhage, perforation, pseudo-obstruction, pneumatosis cystoides intestinalis, and spontaneous abdominal haematoma1-4 6-8. We recently observed a new case, which is of particular interest. The patient who had DM refractory to steroids and both gastrointestinal haemorrhage related to vasculitis and oesophageal impairment due to DM experienced a rapid and complete resolution of all clinical manifestations after intravenous immunoglobulin treatment was started.An 18 year old man had DM evolving from March 1999. The diagnosis of DM was made by the Bohan and Peter criteria9 10: ( a ) symmetrical muscle weakness. Muscle power was gauged for eight proximal muscles (neck flexors, trapezius, deltoid, biceps, psoas, maximus and medius gluteus, and quadriceps) by a modification of the British Medical Research Council Grading system,5 resulting in a theoretical maximum score of 88 points. Muscle power of the patient was 73 points; ( b ) increased serum muscle enzymes—that is, creatine kinase …" @default.
- W2153767402 created "2016-06-24" @default.
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- W2153767402 date "2001-07-01" @default.
- W2153767402 modified "2023-10-17" @default.
- W2153767402 title "Intravenous immunoglobulin for treatment of gastro- intestinal haemorrhage in dermatomyositis" @default.
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- W2153767402 doi "https://doi.org/10.1136/ard.60.7.723" @default.
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