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• W2153777219 abstract "Abstract Functional genomic technologies are generating vast amounts of data describing the presence of transcripts or proteins in plant cells. Together with classical genetics, these approaches broaden our understanding of the gene products required for specific responses. Looking to the future, the focus of research must shift to the dynamic aspects of biology: molecular mechanisms of function and regulation. Phosphorylation is a key regulatory factor in all aspects of plant biology; but it is difficult, if not impossible, for most researchers to identify in vivo phosphorylation sites within their proteins of interest. We have developed a large-scale strategy for the isolation of phosphopeptides and identification by mass spectrometry (Nühse et al., 2003b). Here, we describe the identification of more than 300 phosphorylation sites from Arabidopsis thaliana plasma membrane proteins. These data will be a valuable resource for many fields of plant biology and overcome a major impediment to the elucidation of signal transduction pathways. We present an analysis of the characteristics of phosphorylation sites, their conservation among orthologs and paralogs, and the existence of putative motifs surrounding the sites. These analyses yield general principles for predicting other phosphorylation sites in plants and provide indications of specificity determinants for responsible kinases. In addition, more than 50 sites were mapped on receptor-like kinases and revealed an unexpected complexity of regulation. Finally, the data also provide empirical evidence on the topology of transmembrane proteins. This information indicates that prediction programs incorrectly identified the cytosolic portion of the protein in 25% of the transmembrane proteins found in this study. All data are deposited in a new searchable database for plant phosphorylation sites maintained by PlantsP (http://plantsp.sdsc.edu) that will be updated as the project expands to encompass additional tissues and organelles." @default.
• W2153777219 created "2016-06-24" @default.
• W2153777219 creator A5018229472 @default.
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• W2153777219 creator A5054557695 @default.
• W2153777219 creator A5070281679 @default.
• W2153777219 date "2004-09-01" @default.
• W2153777219 modified "2023-10-16" @default.
• W2153777219 title "Phosphoproteomics of the Arabidopsis Plasma Membrane and a New Phosphorylation Site Database[W]" @default.
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• W2153777219 cites W1983255121 @default.
• W2153777219 cites W1989092454 @default.
• W2153777219 cites W1992945955 @default.
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• W2153777219 cites W2007494100 @default.
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• W2153777219 doi "https://doi.org/10.1105/tpc.104.023150" @default.
• W2153777219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/520941" @default.
• W2153777219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15308754" @default.
• W2153777219 hasPublicationYear "2004" @default.
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