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• W2153851224 abstract "During pregnancy, fetal growth causes an increase in the total number of rapidly dividing cells, which leads to increased requirements for folate. Inadequate folate intake leads to a decrease in serum folate concentration, resulting in a decrease in erythrocyte folate concentration, a rise in homocysteine concentration, and megaloblastic changes in the bone marrow and other tissues with rapidly dividing cellsTo assess the effectiveness of oral folic acid supplementation alone or with other micronutrients versus no folic acid (placebo or same micronutrients but no folic acid) during pregnancy on haematological and biochemical parameters during pregnancy and on pregnancy outcomes.We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 December 2012) and we contacted major organisations working in micronutrient supplementation, including UNICEF Nutrition Section, World Health Organization (WHO) Maternal and Reproductive Health, WHO Nutrition Division, and National Center on Birth defects and Developmnetal Disabilities, US Centers for Disease Control and Prevention (CDC).All randomised, cluster-randomised and cross-over controlled trials evaluating supplementation of folic acid alone or with other micronutrients versus no folic acid (placebo or same micronutrients but no folic acid) in pregnancy.Two review authors independently assessed trials for inclusion, assessed risk of bias and extracted data. Data were checked for accuracy.Thirty-one trials involving 17,771 women are included in this review. This review found that folic acid supplementation has no impact on pregnancy outcomes such as preterm birth (risk ratio (RR) 1.01, 95% confidence interval (CI) 0.73 to 1.38; three studies, 2959 participants), and stillbirths/neonatal deaths (RR 1.33, 95% CI 0.96 to 1.85; three studies, 3110 participants). However, improvements were seen in the mean birthweight (mean difference (MD) 135.75, 95% CI 47.85 to 223.68). On the other hand, the review found no impact on improving pre-delivery anaemia (average RR 0.62, 95% CI 0.35 to 1.10; eight studies, 4149 participants; random-effects), mean pre-delivery haemoglobin level (MD -0.03, 95% CI -0.25 to 0.19; 12 studies, 1806 participants), mean pre-delivery serum folate levels (standardised mean difference (SMD) 2.03, 95% CI 0.80 to 3.27; eight studies, 1250 participants; random-effects), and mean pre-delivery red cell folate levels (SMD 1.59, 95% CI -0.07 to 3.26; four studies, 427 participants; random-effects). However, a significant reduction was seen in the incidence of megaloblastic anaemia (RR 0.21, 95% CI 0.11 to 0.38, four studies, 3839 participants).We found no conclusive evidence of benefit of folic acid supplementation during pregnancy on pregnancy outcomes." @default.
• W2153851224 created "2016-06-24" @default.
• W2153851224 creator A5020054157 @default.
• W2153851224 creator A5031009188 @default.
• W2153851224 creator A5044131184 @default.
• W2153851224 creator A5063944341 @default.
• W2153851224 date "2013-03-28" @default.
• W2153851224 modified "2023-10-10" @default.
• W2153851224 title "Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes" @default.
• W2153851224 cites W110385290 @default.
• W2153851224 cites W113793698 @default.
• W2153851224 cites W146029217 @default.
• W2153851224 cites W1481448793 @default.
• W2153851224 cites W1503239084 @default.
• W2153851224 cites W1514273892 @default.
• W2153851224 cites W1520233856 @default.
• W2153851224 cites W1530782354 @default.
• W2153851224 cites W1535278102 @default.
• W2153851224 cites W1567287877 @default.
• W2153851224 cites W1678942826 @default.
• W2153851224 cites W1782150332 @default.
• W2153851224 cites W1785122941 @default.
• W2153851224 cites W1788462375 @default.
• W2153851224 cites W1793110720 @default.
• W2153851224 cites W1879524379 @default.
• W2153851224 cites W1892263002 @default.
• W2153851224 cites W1892783351 @default.
• W2153851224 cites W1903089608 @default.
• W2153851224 cites W1925335316 @default.
• W2153851224 cites W194944240 @default.
• W2153851224 cites W1969093999 @default.
• W2153851224 cites W1972061890 @default.
• W2153851224 cites W1977663393 @default.
• W2153851224 cites W1977960291 @default.
• W2153851224 cites W1978469826 @default.
• W2153851224 cites W1978929725 @default.
• W2153851224 cites W1983204623 @default.
• W2153851224 cites W1986390516 @default.
• W2153851224 cites W1994129786 @default.
• W2153851224 cites W1995477181 @default.
• W2153851224 cites W1995625448 @default.
• W2153851224 cites W1995781460 @default.
• W2153851224 cites W1995877613 @default.
• W2153851224 cites W1996818735 @default.
• W2153851224 cites W1997103687 @default.
• W2153851224 cites W1997797761 @default.
• W2153851224 cites W1999475672 @default.
• W2153851224 cites W1999968416 @default.
• W2153851224 cites W2002615491 @default.
• W2153851224 cites W2004448236 @default.
• W2153851224 cites W2006080850 @default.
• W2153851224 cites W2008145113 @default.
• W2153851224 cites W2013599170 @default.
• W2153851224 cites W2020092748 @default.
• W2153851224 cites W2027804269 @default.
• W2153851224 cites W2030771384 @default.
• W2153851224 cites W2035139851 @default.
• W2153851224 cites W2036021443 @default.
• W2153851224 cites W2036324911 @default.
• W2153851224 cites W2040710267 @default.
• W2153851224 cites W2040846418 @default.
• W2153851224 cites W2047432037 @default.
• W2153851224 cites W2049835756 @default.
• W2153851224 cites W2050099237 @default.
• W2153851224 cites W2054687628 @default.
• W2153851224 cites W2059800381 @default.
• W2153851224 cites W2061186888 @default.
• W2153851224 cites W2064054833 @default.
• W2153851224 cites W2064833775 @default.
• W2153851224 cites W2069636478 @default.
• W2153851224 cites W2077550734 @default.
• W2153851224 cites W2085324843 @default.
• W2153851224 cites W2089303692 @default.
• W2153851224 cites W2089953555 @default.
• W2153851224 cites W2090884768 @default.
• W2153851224 cites W2097442349 @default.
• W2153851224 cites W2100290760 @default.
• W2153851224 cites W2102730298 @default.
• W2153851224 cites W2103348965 @default.
• W2153851224 cites W2104292590 @default.
• W2153851224 cites W2104654612 @default.
• W2153851224 cites W2108440277 @default.
• W2153851224 cites W2111313677 @default.
• W2153851224 cites W2111813063 @default.
• W2153851224 cites W2113689285 @default.
• W2153851224 cites W2114652914 @default.
• W2153851224 cites W2116959209 @default.
• W2153851224 cites W2118107568 @default.
• W2153851224 cites W2122636433 @default.
• W2153851224 cites W2124302027 @default.
• W2153851224 cites W2126953458 @default.
• W2153851224 cites W2127747029 @default.
• W2153851224 cites W2127751097 @default.
• W2153851224 cites W2132751163 @default.
• W2153851224 cites W2134522444 @default.
• W2153851224 cites W2137436244 @default.
• W2153851224 cites W2137541190 @default.
• W2153851224 cites W2138653044 @default.
• W2153851224 cites W2143731308 @default.
• W2153851224 cites W2144170232 @default.

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