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- W2153893212 abstract "La carence d'α-antitrypsine (αAT) (PIZZ) est frequente dans la population scandinave et predisposee a des maladies pulmonaires et hepatiques. Un nouveau-ne sur 9600 est homozygote (PIZZ) pour cette erreur congenitale et 5% sont heterozygotes (PIMZ). Environ 90% des nouveau-nes homozygotes presenteront une hepatite neonatale ne comportant pas necessairement un mauvais pronostic. L'incidence de la cirrhose chez les hommes adultes homozygotes est augmentee mais la cirrhose est rarement manifeste cliniquement avant l'âge de 50 ans. La degenerescence maligne est une complication frequente. Certains heterozygotes, peut-etre 90 a 95% presenteront une hepatopathie chronique" @default.
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- W2153893212 date "1985-01-01" @default.
- W2153893212 modified "2023-10-16" @default.
- W2153893212 title "Liver Disease in α<sub>1</sub>-Antitrypsin Deficiency: Aspects of Incidence and Prognosis" @default.
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- W2153893212 doi "https://doi.org/10.3109/00365528509088844" @default.
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