FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153977993> ?p ?o ?g. }

• W2153977993 endingPage "655" @default.
• W2153977993 startingPage "649" @default.
• W2153977993 abstract "The purpose of the present study was to determine the effect of chronic alcohol consumption on reactivity of esophageal tunica muscularis mucosae (TMM) and lower esophageal sphincter (LES) smooth muscle. Six male rats in alcohol-fed group received ethanol (7.2% v/v) in a modified liquid diet for 4 weeks. Two control groups were used; six rats in the standard diet-fed group received rat chow and water for 4 weeks. Six rats in sucrose-fed group were given sucrose and received a liquid diet. The smooth muscle reactivity of TMM and LES strips from ethanol-fed and control animals was evaluated in organ chambers. Also histologic study was undertaken to show effects of chronic alcohol consumption. Maximum contractile responses of TMM to KCl and carbachol were decreased in the ethanol-fed group compared to the control groups. Relaxant responses to serotonin were decreased in the ethanol-fed group compared to the control groups. In TMM, isoproterenol- and papaverine-induced relaxant responses were similar in the ethanol-fed and control groups. In LES smooth muscle, relaxant responses to papaverine or isoproterenol were similar in the control groups and the ethanol-fed group. There was no change in agonist potency among the groups. The relaxation response elicited by nicotine and sodium nitroprusside (SNP) or contractile response elicited by carbachol and 80 mM KCl was decreased with maximum responses and pD2 values, in the ethanol-fed group compared to that of the control groups in LES. Decreased nNOS immunoreactivity in myenteric plexus was found in alcohol-exposed group compared to control groups. Our findings suggest that chronic alcohol consumption impairs relaxant and contractile responses of both TMM and LES smooth muscle and it may contribute to gastroesophageal reflux commonly seen after alcohol binges." @default.
• W2153977993 created "2016-06-24" @default.
• W2153977993 creator A5007960097 @default.
• W2153977993 creator A5073695430 @default.
• W2153977993 creator A5074185258 @default.
• W2153977993 creator A5077836439 @default.
• W2153977993 date "2012-11-01" @default.
• W2153977993 modified "2023-10-02" @default.
• W2153977993 title "Effects of chronic ethanol consumption on rat upper gastrointestinal system: Functional and histologic findings" @default.
• W2153977993 cites W1746875878 @default.
• W2153977993 cites W1973041952 @default.
• W2153977993 cites W1974133987 @default.
• W2153977993 cites W1975661708 @default.
• W2153977993 cites W1997807930 @default.
• W2153977993 cites W1997814515 @default.
• W2153977993 cites W2009231679 @default.
• W2153977993 cites W2014479584 @default.
• W2153977993 cites W2014770759 @default.
• W2153977993 cites W2028399875 @default.
• W2153977993 cites W2029176210 @default.
• W2153977993 cites W2029519062 @default.
• W2153977993 cites W2031907840 @default.
• W2153977993 cites W2042537317 @default.
• W2153977993 cites W2056169163 @default.
• W2153977993 cites W2064430732 @default.
• W2153977993 cites W2073618617 @default.
• W2153977993 cites W2073713671 @default.
• W2153977993 cites W2076899974 @default.
• W2153977993 cites W2079027721 @default.
• W2153977993 cites W2079885393 @default.
• W2153977993 cites W2091743218 @default.
• W2153977993 cites W2091753679 @default.
• W2153977993 cites W2092423804 @default.
• W2153977993 cites W2097651829 @default.
• W2153977993 cites W2100571851 @default.
• W2153977993 cites W2102162403 @default.
• W2153977993 cites W2109229257 @default.
• W2153977993 cites W2120873478 @default.
• W2153977993 cites W2122056886 @default.
• W2153977993 cites W2130442612 @default.
• W2153977993 cites W2131518373 @default.
• W2153977993 cites W2138396325 @default.
• W2153977993 cites W2157824267 @default.
• W2153977993 cites W2315787720 @default.
• W2153977993 doi "https://doi.org/10.1016/j.alcohol.2012.06.003" @default.
• W2153977993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22818204" @default.
• W2153977993 hasPublicationYear "2012" @default.
• W2153977993 type Work @default.
• W2153977993 sameAs 2153977993 @default.
• W2153977993 citedByCount "7" @default.
• W2153977993 countsByYear W21539779932014 @default.
• W2153977993 countsByYear W21539779932015 @default.
• W2153977993 countsByYear W21539779932019 @default.
• W2153977993 countsByYear W21539779932020 @default.
• W2153977993 crossrefType "journal-article" @default.
• W2153977993 hasAuthorship W2153977993A5007960097 @default.
• W2153977993 hasAuthorship W2153977993A5073695430 @default.
• W2153977993 hasAuthorship W2153977993A5074185258 @default.
• W2153977993 hasAuthorship W2153977993A5077836439 @default.
• W2153977993 hasConcept C126322002 @default.
• W2153977993 hasConcept C134018914 @default.
• W2153977993 hasConcept C170493617 @default.
• W2153977993 hasConcept C185592680 @default.
• W2153977993 hasConcept C204232928 @default.
• W2153977993 hasConcept C24998067 @default.
• W2153977993 hasConcept C2775859210 @default.
• W2153977993 hasConcept C2776907353 @default.
• W2153977993 hasConcept C2776952824 @default.
• W2153977993 hasConcept C2778349201 @default.
• W2153977993 hasConcept C2778938600 @default.
• W2153977993 hasConcept C2778988552 @default.
• W2153977993 hasConcept C2779610285 @default.
• W2153977993 hasConcept C2780161600 @default.
• W2153977993 hasConcept C519581460 @default.
• W2153977993 hasConcept C55493867 @default.
• W2153977993 hasConcept C71924100 @default.
• W2153977993 hasConceptScore W2153977993C126322002 @default.
• W2153977993 hasConceptScore W2153977993C134018914 @default.
• W2153977993 hasConceptScore W2153977993C170493617 @default.
• W2153977993 hasConceptScore W2153977993C185592680 @default.
• W2153977993 hasConceptScore W2153977993C204232928 @default.
• W2153977993 hasConceptScore W2153977993C24998067 @default.
• W2153977993 hasConceptScore W2153977993C2775859210 @default.
• W2153977993 hasConceptScore W2153977993C2776907353 @default.
• W2153977993 hasConceptScore W2153977993C2776952824 @default.
• W2153977993 hasConceptScore W2153977993C2778349201 @default.
• W2153977993 hasConceptScore W2153977993C2778938600 @default.
• W2153977993 hasConceptScore W2153977993C2778988552 @default.
• W2153977993 hasConceptScore W2153977993C2779610285 @default.
• W2153977993 hasConceptScore W2153977993C2780161600 @default.
• W2153977993 hasConceptScore W2153977993C519581460 @default.
• W2153977993 hasConceptScore W2153977993C55493867 @default.
• W2153977993 hasConceptScore W2153977993C71924100 @default.
• W2153977993 hasIssue "7" @default.
• W2153977993 hasLocation W21539779931 @default.
• W2153977993 hasLocation W21539779932 @default.
• W2153977993 hasOpenAccess W2153977993 @default.
• W2153977993 hasPrimaryLocation W21539779931 @default.

• next