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• W2154037653 endingPage "1920" @default.
• W2154037653 startingPage "1916" @default.
• W2154037653 abstract "Except for taste bud cells, all sensory receptor cells and neurons have been shown to originate from neurogenic ectoderm (i.e., neural tube, neural crest, or ectodermal placodes). Descriptive studies on taste buds indicate that they, however, may arise from local epithelium. To determine whether taste receptor cells originate from neurogenic ectoderm or from local epithelium, the tongues of X chromosome-inactivation mosaic mice were examined. Results of this analysis show that taste bud cells and their surrounding epithelium always match in terms of the mosaic marker. This suggests that taste cells and epithelial cells arise from a common progenitor and that taste receptor cells originate from local tissue elements. Since taste buds are widespread in the oropharynx, they lie in epithelium derived from both ectoderm and endoderm. Therefore, taste receptor cells can be induced in tissue from two different germ layers. Thus in terms of tissues of origin, taste receptor cells are unlike other cells with neuronal characteristics." @default.
• W2154037653 created "2016-06-24" @default.
• W2154037653 creator A5028759832 @default.
• W2154037653 creator A5049883489 @default.
• W2154037653 creator A5066701254 @default.
• W2154037653 creator A5067443757 @default.
• W2154037653 date "1995-03-14" @default.
• W2154037653 modified "2023-10-06" @default.
• W2154037653 title "Taste receptor cells arise from local epithelium, not neurogenic ectoderm." @default.
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• W2154037653 doi "https://doi.org/10.1073/pnas.92.6.1916" @default.
• W2154037653 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/42393" @default.
• W2154037653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7892199" @default.
• W2154037653 hasPublicationYear "1995" @default.
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