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- W2154077853 abstract "Due to their complexity, electrochemically active biofilms must be studied with a multidisciplinary mindset, bringing together ideas and techniques from multiple fields. Mathematical modeling is a powerful tool that can provide a unifying framework for theories and data from the disparate and multidisciplinary fields of biofilm research. In this chapter, our goal was to develop a model capable of simulating two simultaneous electron transfer mechanisms in electrochemically active biofilms and demonstrate the practical implementation of this model using a MATLAB® client connection to run finite element method software Comsol Multiphysics®. Evidence in the literature suggests that some biofilms, particularly Shewanella oneidensis, produce the requisite components for multiple extracellular electron transfer mechanisms. In this study, a generic model is presented that incorporates diffusion- and conduction-based mechanisms and allows electrochemically active biofilms to utilize both mechanisms simultaneously. The model was applied to S. oneidensis and Geobacter sulfurreducens biofilms using experimentally generated data found in the literature. Our simulation results show that (1) biofilms having both mechanisms available, especially if they can interact, may have a metabolic advantage over biofilms that can use only a single mechanism; (2) the thickness of G. sulfurreducens biofilms is likely not limited by conductivity; (3) accurate intrabiofilm diffusion coefficient values are critical for current generation predictions; and (4) the local biofilm potential and redox potential are two distinct parameters and cannot be assumed to have identical values. Finally, we determined that simulated cyclic and squarewave voltammetry based on our model are currently not capable of determining the specific percentages of extracellular electron transfer mechanisms in a biofilm. This chapter shows how mathematical modeling can be used as a unifying tool for investigating electrochemically active biofilms and electron transfer mechanisms." @default.
- W2154077853 created "2016-06-24" @default.
- W2154077853 creator A5000612492 @default.
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- W2154077853 creator A5051101756 @default.
- W2154077853 creator A5054071526 @default.
- W2154077853 creator A5071097322 @default.
- W2154077853 date "2015-09-08" @default.
- W2154077853 modified "2023-10-12" @default.
- W2154077853 title "Mathematical Modeling of Extracellular Electron Transfer in Biofilms" @default.
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