FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154129080> ?p ?o ?g. }

• W2154129080 endingPage "311" @default.
• W2154129080 startingPage "302" @default.
• W2154129080 abstract "Despite many years of studies on the mechanisms of immunological defence responses induced in host organisms by Toxoplasma, no satisfactory immunoprophylaxis or chemotherapy have yet been established for humans. Thus, alternative methods to prevent toxoplasmosis and to enhance the efficacy of currently used antitoxoplasmic drugs are under evaluation. In this work, we strove to determine the influence of human prolactin (endogenous present in serum--sPRL and recombinant--rhPRL) on the course of Toxoplasma infection of peripheral blood mononuclear cells (PBMC) originating from female hyperprolactinemia patients. This study revealed that exogenous rhPRL as well as autologous sPRL from inactivated sera significantly restricted intracellular growth of Toxoplasma in PBMC cultures. Moreover, analysis of IL-10 production by PBMC infected with Toxoplasma and cultured in the presence of sPRL showed a positive correlation between sPRL concentration and the level of IL-10. The obtained results could indicate the possible protective action of PRL in a host organism infected with Toxoplasma and suggest that a significant increase in the serum PRL level, during pregnancy for instance, might significantly limit the risk of Toxoplasma spreading and could play an important role in natural protection against toxoplasmosis. The mechanism of inhibitory effect of PRL needs further detailed study." @default.
• W2154129080 created "2016-06-24" @default.
• W2154129080 creator A5008661550 @default.
• W2154129080 creator A5010072762 @default.
• W2154129080 creator A5024838166 @default.
• W2154129080 creator A5038054105 @default.
• W2154129080 creator A5050406527 @default.
• W2154129080 creator A5059366197 @default.
• W2154129080 date "2012-05-11" @default.
• W2154129080 modified "2023-10-03" @default.
• W2154129080 title "Inhibitory effect of prolactin on Toxoplasma proliferation in peripheral blood mononuclear cells from patients with hyperprolactinemia" @default.
• W2154129080 cites W15407895 @default.
• W2154129080 cites W1970140452 @default.
• W2154129080 cites W1979307276 @default.
• W2154129080 cites W1985627448 @default.
• W2154129080 cites W1987980394 @default.
• W2154129080 cites W1995026222 @default.
• W2154129080 cites W1995732889 @default.
• W2154129080 cites W2001742471 @default.
• W2154129080 cites W2005348075 @default.
• W2154129080 cites W2012445733 @default.
• W2154129080 cites W2015559526 @default.
• W2154129080 cites W2028104642 @default.
• W2154129080 cites W2033437855 @default.
• W2154129080 cites W2035442089 @default.
• W2154129080 cites W2041953360 @default.
• W2154129080 cites W2042631134 @default.
• W2154129080 cites W2056738684 @default.
• W2154129080 cites W2064962821 @default.
• W2154129080 cites W2067918524 @default.
• W2154129080 cites W2074357767 @default.
• W2154129080 cites W2075950282 @default.
• W2154129080 cites W2079409189 @default.
• W2154129080 cites W2081530584 @default.
• W2154129080 cites W2113103296 @default.
• W2154129080 cites W2113173126 @default.
• W2154129080 cites W2117197980 @default.
• W2154129080 cites W2131314467 @default.
• W2154129080 cites W2132631354 @default.
• W2154129080 cites W2133868033 @default.
• W2154129080 cites W2136097155 @default.
• W2154129080 cites W2163369593 @default.
• W2154129080 cites W2165195703 @default.
• W2154129080 cites W4237144135 @default.
• W2154129080 cites W4253803234 @default.
• W2154129080 doi "https://doi.org/10.1111/j.1365-3024.2012.01359.x" @default.
• W2154129080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22364553" @default.
• W2154129080 hasPublicationYear "2012" @default.
• W2154129080 type Work @default.
• W2154129080 sameAs 2154129080 @default.
• W2154129080 citedByCount "11" @default.
• W2154129080 countsByYear W21541290802013 @default.
• W2154129080 countsByYear W21541290802014 @default.
• W2154129080 countsByYear W21541290802015 @default.
• W2154129080 countsByYear W21541290802018 @default.
• W2154129080 countsByYear W21541290802019 @default.
• W2154129080 countsByYear W21541290802022 @default.
• W2154129080 countsByYear W21541290802023 @default.
• W2154129080 crossrefType "journal-article" @default.
• W2154129080 hasAuthorship W2154129080A5008661550 @default.
• W2154129080 hasAuthorship W2154129080A5010072762 @default.
• W2154129080 hasAuthorship W2154129080A5024838166 @default.
• W2154129080 hasAuthorship W2154129080A5038054105 @default.
• W2154129080 hasAuthorship W2154129080A5050406527 @default.
• W2154129080 hasAuthorship W2154129080A5059366197 @default.
• W2154129080 hasConcept C134018914 @default.
• W2154129080 hasConcept C137061746 @default.
• W2154129080 hasConcept C159654299 @default.
• W2154129080 hasConcept C202751555 @default.
• W2154129080 hasConcept C203014093 @default.
• W2154129080 hasConcept C2778062946 @default.
• W2154129080 hasConcept C2778128430 @default.
• W2154129080 hasConcept C2779064019 @default.
• W2154129080 hasConcept C2779234561 @default.
• W2154129080 hasConcept C54355233 @default.
• W2154129080 hasConcept C55493867 @default.
• W2154129080 hasConcept C71315377 @default.
• W2154129080 hasConcept C86803240 @default.
• W2154129080 hasConceptScore W2154129080C134018914 @default.
• W2154129080 hasConceptScore W2154129080C137061746 @default.
• W2154129080 hasConceptScore W2154129080C159654299 @default.
• W2154129080 hasConceptScore W2154129080C202751555 @default.
• W2154129080 hasConceptScore W2154129080C203014093 @default.
• W2154129080 hasConceptScore W2154129080C2778062946 @default.
• W2154129080 hasConceptScore W2154129080C2778128430 @default.
• W2154129080 hasConceptScore W2154129080C2779064019 @default.
• W2154129080 hasConceptScore W2154129080C2779234561 @default.
• W2154129080 hasConceptScore W2154129080C54355233 @default.
• W2154129080 hasConceptScore W2154129080C55493867 @default.
• W2154129080 hasConceptScore W2154129080C71315377 @default.
• W2154129080 hasConceptScore W2154129080C86803240 @default.
• W2154129080 hasIssue "6" @default.
• W2154129080 hasLocation W21541290801 @default.
• W2154129080 hasLocation W21541290802 @default.
• W2154129080 hasOpenAccess W2154129080 @default.
• W2154129080 hasPrimaryLocation W21541290801 @default.
• W2154129080 hasRelatedWork W1967728126 @default.
• W2154129080 hasRelatedWork W1985115278 @default.

• next