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- W2154132815 abstract "The activation of CD8+ T-cells requires the uptake of exogenous polypeptide antigens and proteolytic processing of these antigens to octamer or nonamer peptides, which are loaded on MHC-I complexes and presented to the T-cell. By using an azide as a bioorthogonal protecting group rather than as a ligation handle, masked antigens were generated—antigens that are not recognized by their cognate T-cell unless they are deprotected on the cell using a Staudinger reduction." @default.
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- W2154132815 date "2015-03-17" @default.
- W2154132815 modified "2023-09-27" @default.
- W2154132815 title "Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation" @default.
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- W2154132815 doi "https://doi.org/10.1002/anie.201500301" @default.
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