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- W2154156676 abstract "ABSTRACT Insulin antibodies were studied in the maternal and foetal plasma of pregnant guinea pig immunized against insulin. By paper-electrophoresis an insulin binding globulin was found in mother and offspring. Radioimmunoelectrophoretic analysis showed insulin binding antibodies of three types in maternal plasma, i. e. in γ 1 –γ 2 - and γ M -globulins. Foetal plasma only showed antibody activities in γ 1 - and γ 2 -globulins. The insulin binding capacity was practically identical in maternal and foetal plasma. Foetuses of passively immunized mothers also showed antibody activity in plasma. The antibody titres of amniotic fluid averaged 1/100 of the plasma titres. The disappearance of the insulin antibodies after birth was followed in six offspring. The mean of their half-lifes was 8 days." @default.
- W2154156676 created "2016-06-24" @default.
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- W2154156676 date "1966-06-01" @default.
- W2154156676 modified "2023-10-18" @default.
- W2154156676 title "INSULIN ANTIBODIES IN PREGNANT GUINEA PIGS AND IN THEIR OFFSPRING" @default.
- W2154156676 doi "https://doi.org/10.1530/acta.0.0520255" @default.
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