FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154168767> ?p ?o ?g. }

• W2154168767 endingPage "n/a" @default.
• W2154168767 startingPage "n/a" @default.
• W2154168767 abstract "Dopamine excess appears to be critical in the final common pathway of delirium. The aim of this study was to investigate whether genetic polymorphisms in three dopamine-related genes (the dopamine receptor 2 (DRD2), dopamine receptor 3 (DRD3), and the dopamine transporter (SLC6A3) gene) were associated with delirium. Patients aged 65 years and older acutely admitted to the medical department or to the surgical department following hip fracture were included. Delirium was diagnosed by the Confusion Assessment Method. Sixteen single nucleotide polymorphisms (SNPs) and one variable number of tandem repeats in the SLC6A3 gene, nine SNPs in the DRD2 gene, and six SNPs in the DRD3 gene were genotyped. Fifty percent of the 115 surgical patients and 34% of the 605 medical patients experienced delirium. Delirious patients were older and had more frequently pre-existing functional and cognitive impairment (P < 0.001). After correction for multiple testing, one SNP in the SLC6A3 gene (rs393795) was associated with reduced risk of delirium (P = 0.032). Adjusted for age, cognitive impairment, and functional impairment, three SNPs in the DRD2 gene and seven SNPs in the SLC6A3 gene were associated with delirium; none of these associations was significant after correction for multiple testing. Variations in the SLC6A3 gene and possibly the DRD2 gene were associated with delirium. Although validation of these results is needed our results support a role for the dopamine transporter and dopamine receptor 2 in the pathogenesis of delirium. © 2009 Wiley-Liss, Inc." @default.
• W2154168767 created "2016-06-24" @default.
• W2154168767 creator A5015849613 @default.
• W2154168767 creator A5024730616 @default.
• W2154168767 creator A5041406792 @default.
• W2154168767 creator A5051056050 @default.
• W2154168767 creator A5061012556 @default.
• W2154168767 creator A5078029571 @default.
• W2154168767 creator A5080723184 @default.
• W2154168767 creator A5081601973 @default.
• W2154168767 date "2009-01-01" @default.
• W2154168767 modified "2023-10-12" @default.
• W2154168767 title "Genetic polymorphisms in the DRD2, DRD3, and SLC6A3 gene in elderly patients with delirium" @default.
• W2154168767 cites W1847168837 @default.
• W2154168767 cites W1969314235 @default.
• W2154168767 cites W1978502700 @default.
• W2154168767 cites W1981927227 @default.
• W2154168767 cites W2008133020 @default.
• W2154168767 cites W2013243127 @default.
• W2154168767 cites W2019445205 @default.
• W2154168767 cites W2036985020 @default.
• W2154168767 cites W2038444868 @default.
• W2154168767 cites W2038846656 @default.
• W2154168767 cites W2041019422 @default.
• W2154168767 cites W2045612157 @default.
• W2154168767 cites W2045906787 @default.
• W2154168767 cites W2047449436 @default.
• W2154168767 cites W2050140838 @default.
• W2154168767 cites W2059156466 @default.
• W2154168767 cites W2063353650 @default.
• W2154168767 cites W2064313010 @default.
• W2154168767 cites W2074584886 @default.
• W2154168767 cites W2081033553 @default.
• W2154168767 cites W2086015715 @default.
• W2154168767 cites W2088829922 @default.
• W2154168767 cites W2122196056 @default.
• W2154168767 cites W2126445511 @default.
• W2154168767 cites W2132783892 @default.
• W2154168767 cites W2133612117 @default.
• W2154168767 cites W2134535009 @default.
• W2154168767 cites W2137412250 @default.
• W2154168767 cites W2140915307 @default.
• W2154168767 cites W2152664025 @default.
• W2154168767 cites W2162530578 @default.
• W2154168767 doi "https://doi.org/10.1002/ajmg.b.30943" @default.
• W2154168767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19309018" @default.
• W2154168767 hasPublicationYear "2009" @default.
• W2154168767 type Work @default.
• W2154168767 sameAs 2154168767 @default.
• W2154168767 citedByCount "11" @default.
• W2154168767 countsByYear W21541687672013 @default.
• W2154168767 countsByYear W21541687672014 @default.
• W2154168767 countsByYear W21541687672015 @default.
• W2154168767 countsByYear W21541687672017 @default.
• W2154168767 countsByYear W21541687672019 @default.
• W2154168767 countsByYear W21541687672021 @default.
• W2154168767 countsByYear W21541687672023 @default.
• W2154168767 crossrefType "journal-article" @default.
• W2154168767 hasAuthorship W2154168767A5015849613 @default.
• W2154168767 hasAuthorship W2154168767A5024730616 @default.
• W2154168767 hasAuthorship W2154168767A5041406792 @default.
• W2154168767 hasAuthorship W2154168767A5051056050 @default.
• W2154168767 hasAuthorship W2154168767A5061012556 @default.
• W2154168767 hasAuthorship W2154168767A5078029571 @default.
• W2154168767 hasAuthorship W2154168767A5080723184 @default.
• W2154168767 hasAuthorship W2154168767A5081601973 @default.
• W2154168767 hasBestOaLocation W21541687672 @default.
• W2154168767 hasConcept C104317684 @default.
• W2154168767 hasConcept C118552586 @default.
• W2154168767 hasConcept C120069818 @default.
• W2154168767 hasConcept C126322002 @default.
• W2154168767 hasConcept C135763542 @default.
• W2154168767 hasConcept C137183658 @default.
• W2154168767 hasConcept C139275648 @default.
• W2154168767 hasConcept C153209595 @default.
• W2154168767 hasConcept C2776412080 @default.
• W2154168767 hasConcept C2776755682 @default.
• W2154168767 hasConcept C2777393122 @default.
• W2154168767 hasConcept C2779753318 @default.
• W2154168767 hasConcept C2780494398 @default.
• W2154168767 hasConcept C513476851 @default.
• W2154168767 hasConcept C54355233 @default.
• W2154168767 hasConcept C71924100 @default.
• W2154168767 hasConcept C86803240 @default.
• W2154168767 hasConceptScore W2154168767C104317684 @default.
• W2154168767 hasConceptScore W2154168767C118552586 @default.
• W2154168767 hasConceptScore W2154168767C120069818 @default.
• W2154168767 hasConceptScore W2154168767C126322002 @default.
• W2154168767 hasConceptScore W2154168767C135763542 @default.
• W2154168767 hasConceptScore W2154168767C137183658 @default.
• W2154168767 hasConceptScore W2154168767C139275648 @default.
• W2154168767 hasConceptScore W2154168767C153209595 @default.
• W2154168767 hasConceptScore W2154168767C2776412080 @default.
• W2154168767 hasConceptScore W2154168767C2776755682 @default.
• W2154168767 hasConceptScore W2154168767C2777393122 @default.
• W2154168767 hasConceptScore W2154168767C2779753318 @default.
• W2154168767 hasConceptScore W2154168767C2780494398 @default.
• W2154168767 hasConceptScore W2154168767C513476851 @default.

• next