FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154187831> ?p ?o ?g. }

• W2154187831 endingPage "543" @default.
• W2154187831 startingPage "533" @default.
• W2154187831 abstract "The homeostatic control of membrane lipid composition appears to be of central importance for cell functioning and survival. However, while lipid biosynthetic reaction networks have been mapped in detail, the underlying control architecture which underpins these networks remains elusive. A key problem in determining the control architectures of lipid biosynthetic pathways, and the mechanisms through which control is achieved, is that the compositional complexity of lipid membranes makes it difficult to determine which membrane parameter is under homeostatic control. Recently, we reported that membrane stored elastic energy provides a physical feedback signal which modulates the activity in vitro of CTP:phosphocholine cytidylyltransferase (CCT), an extrinsic membrane enzyme which catalyses a key step in the synthesis of phosphatidylcholine lipids in the Kennedy pathway (Kennedy 1953 J. Am. Chem. Soc . 75 , 249–250). We postulate that stored elastic energy may be the main property of membranes that is under homeostatic control. Here we report the results of simulations based on this postulate, which reveal a possible control architecture for lipid biosynthesis networks in vivo ." @default.
• W2154187831 created "2016-06-24" @default.
• W2154187831 creator A5014541016 @default.
• W2154187831 creator A5059467964 @default.
• W2154187831 creator A5073554300 @default.
• W2154187831 date "2007-10-16" @default.
• W2154187831 modified "2023-09-25" @default.
• W2154187831 title "Integrative feedback and robustness in a lipid biosynthetic network" @default.
• W2154187831 cites W1500977458 @default.
• W2154187831 cites W1596003471 @default.
• W2154187831 cites W1597119329 @default.
• W2154187831 cites W1963861745 @default.
• W2154187831 cites W1964287788 @default.
• W2154187831 cites W1983159325 @default.
• W2154187831 cites W1986030520 @default.
• W2154187831 cites W2003507857 @default.
• W2154187831 cites W2005630761 @default.
• W2154187831 cites W2006829839 @default.
• W2154187831 cites W2021342960 @default.
• W2154187831 cites W2022636658 @default.
• W2154187831 cites W2030700353 @default.
• W2154187831 cites W2030931359 @default.
• W2154187831 cites W2039857269 @default.
• W2154187831 cites W2044087089 @default.
• W2154187831 cites W2066158193 @default.
• W2154187831 cites W2079163840 @default.
• W2154187831 cites W2090920215 @default.
• W2154187831 cites W2117056464 @default.
• W2154187831 cites W2141941251 @default.
• W2154187831 cites W2170032647 @default.
• W2154187831 cites W2419095632 @default.
• W2154187831 cites W2475948986 @default.
• W2154187831 doi "https://doi.org/10.1098/rsif.2007.1155" @default.
• W2154187831 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3226979" @default.
• W2154187831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17939979" @default.
• W2154187831 hasPublicationYear "2007" @default.
• W2154187831 type Work @default.
• W2154187831 sameAs 2154187831 @default.
• W2154187831 citedByCount "14" @default.
• W2154187831 countsByYear W21541878312013 @default.
• W2154187831 countsByYear W21541878312014 @default.
• W2154187831 countsByYear W21541878312016 @default.
• W2154187831 countsByYear W21541878312017 @default.
• W2154187831 countsByYear W21541878312019 @default.
• W2154187831 countsByYear W21541878312021 @default.
• W2154187831 crossrefType "journal-article" @default.
• W2154187831 hasAuthorship W2154187831A5014541016 @default.
• W2154187831 hasAuthorship W2154187831A5059467964 @default.
• W2154187831 hasAuthorship W2154187831A5073554300 @default.
• W2154187831 hasBestOaLocation W21541878312 @default.
• W2154187831 hasConcept C104317684 @default.
• W2154187831 hasConcept C107565407 @default.
• W2154187831 hasConcept C12554922 @default.
• W2154187831 hasConcept C181199279 @default.
• W2154187831 hasConcept C185592680 @default.
• W2154187831 hasConcept C2776330855 @default.
• W2154187831 hasConcept C2778918659 @default.
• W2154187831 hasConcept C39944091 @default.
• W2154187831 hasConcept C41625074 @default.
• W2154187831 hasConcept C4733338 @default.
• W2154187831 hasConcept C553450214 @default.
• W2154187831 hasConcept C55493867 @default.
• W2154187831 hasConcept C63479239 @default.
• W2154187831 hasConcept C86803240 @default.
• W2154187831 hasConcept C95444343 @default.
• W2154187831 hasConceptScore W2154187831C104317684 @default.
• W2154187831 hasConceptScore W2154187831C107565407 @default.
• W2154187831 hasConceptScore W2154187831C12554922 @default.
• W2154187831 hasConceptScore W2154187831C181199279 @default.
• W2154187831 hasConceptScore W2154187831C185592680 @default.
• W2154187831 hasConceptScore W2154187831C2776330855 @default.
• W2154187831 hasConceptScore W2154187831C2778918659 @default.
• W2154187831 hasConceptScore W2154187831C39944091 @default.
• W2154187831 hasConceptScore W2154187831C41625074 @default.
• W2154187831 hasConceptScore W2154187831C4733338 @default.
• W2154187831 hasConceptScore W2154187831C553450214 @default.
• W2154187831 hasConceptScore W2154187831C55493867 @default.
• W2154187831 hasConceptScore W2154187831C63479239 @default.
• W2154187831 hasConceptScore W2154187831C86803240 @default.
• W2154187831 hasConceptScore W2154187831C95444343 @default.
• W2154187831 hasIssue "22" @default.
• W2154187831 hasLocation W21541878311 @default.
• W2154187831 hasLocation W21541878312 @default.
• W2154187831 hasLocation W21541878313 @default.
• W2154187831 hasLocation W21541878314 @default.
• W2154187831 hasOpenAccess W2154187831 @default.
• W2154187831 hasPrimaryLocation W21541878311 @default.
• W2154187831 hasRelatedWork W1978446484 @default.
• W2154187831 hasRelatedWork W2052531890 @default.
• W2154187831 hasRelatedWork W2069331876 @default.
• W2154187831 hasRelatedWork W2093068573 @default.
• W2154187831 hasRelatedWork W2130174004 @default.
• W2154187831 hasRelatedWork W2418537061 @default.
• W2154187831 hasRelatedWork W2792213734 @default.
• W2154187831 hasRelatedWork W3092932241 @default.
• W2154187831 hasRelatedWork W3110055093 @default.
• W2154187831 hasRelatedWork W3163961232 @default.
• W2154187831 hasVolume "5" @default.

• next