FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154229063> ?p ?o ?g. }

• W2154229063 endingPage "444" @default.
• W2154229063 startingPage "439" @default.
• W2154229063 abstract "Although the polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) is well recognized for its role as a key regulator of cell differentiation, its involvement in tissue regeneration is largely unknown. Here we show that EZH2 is up-regulated following cerulein-induced pancreatic injury and is required for tissue repair by promoting the regenerative proliferation of progenitor cells. Loss of EZH2 results in impaired pancreatic regeneration and accelerates KRas G12D -driven neoplasia. Our findings implicate EZH2 in constraining neoplastic progression through homeostatic mechanisms that control pancreatic regeneration and provide insights into the documented link between chronic pancreatic injury and an increased risk for pancreatic cancer." @default.
• W2154229063 created "2016-06-24" @default.
• W2154229063 creator A5016384926 @default.
• W2154229063 creator A5019945009 @default.
• W2154229063 creator A5025763460 @default.
• W2154229063 creator A5056698491 @default.
• W2154229063 creator A5059165900 @default.
• W2154229063 creator A5061966826 @default.
• W2154229063 creator A5063378046 @default.
• W2154229063 creator A5064775776 @default.
• W2154229063 creator A5078224700 @default.
• W2154229063 creator A5085556621 @default.
• W2154229063 date "2012-03-01" @default.
• W2154229063 modified "2023-10-17" @default.
• W2154229063 title "EZH2 couples pancreatic regeneration to neoplastic progression" @default.
• W2154229063 cites W1965037168 @default.
• W2154229063 cites W1966427973 @default.
• W2154229063 cites W1967081779 @default.
• W2154229063 cites W1988675408 @default.
• W2154229063 cites W1993055783 @default.
• W2154229063 cites W2002355858 @default.
• W2154229063 cites W2008843346 @default.
• W2154229063 cites W2025856640 @default.
• W2154229063 cites W2033406275 @default.
• W2154229063 cites W2042380860 @default.
• W2154229063 cites W2056646351 @default.
• W2154229063 cites W2060608189 @default.
• W2154229063 cites W2066135299 @default.
• W2154229063 cites W2085677283 @default.
• W2154229063 cites W2103456217 @default.
• W2154229063 cites W2106762991 @default.
• W2154229063 cites W2124018740 @default.
• W2154229063 cites W2126663928 @default.
• W2154229063 cites W2130112621 @default.
• W2154229063 cites W2137894910 @default.
• W2154229063 cites W2150053844 @default.
• W2154229063 cites W2158300687 @default.
• W2154229063 cites W2159815377 @default.
• W2154229063 cites W2165110092 @default.
• W2154229063 doi "https://doi.org/10.1101/gad.181800.111" @default.
• W2154229063 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3305982" @default.
• W2154229063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22391448" @default.
• W2154229063 hasPublicationYear "2012" @default.
• W2154229063 type Work @default.
• W2154229063 sameAs 2154229063 @default.
• W2154229063 citedByCount "102" @default.
• W2154229063 countsByYear W21542290632012 @default.
• W2154229063 countsByYear W21542290632013 @default.
• W2154229063 countsByYear W21542290632014 @default.
• W2154229063 countsByYear W21542290632015 @default.
• W2154229063 countsByYear W21542290632016 @default.
• W2154229063 countsByYear W21542290632017 @default.
• W2154229063 countsByYear W21542290632018 @default.
• W2154229063 countsByYear W21542290632019 @default.
• W2154229063 countsByYear W21542290632020 @default.
• W2154229063 countsByYear W21542290632021 @default.
• W2154229063 countsByYear W21542290632022 @default.
• W2154229063 countsByYear W21542290632023 @default.
• W2154229063 crossrefType "journal-article" @default.
• W2154229063 hasAuthorship W2154229063A5016384926 @default.
• W2154229063 hasAuthorship W2154229063A5019945009 @default.
• W2154229063 hasAuthorship W2154229063A5025763460 @default.
• W2154229063 hasAuthorship W2154229063A5056698491 @default.
• W2154229063 hasAuthorship W2154229063A5059165900 @default.
• W2154229063 hasAuthorship W2154229063A5061966826 @default.
• W2154229063 hasAuthorship W2154229063A5063378046 @default.
• W2154229063 hasAuthorship W2154229063A5064775776 @default.
• W2154229063 hasAuthorship W2154229063A5078224700 @default.
• W2154229063 hasAuthorship W2154229063A5085556621 @default.
• W2154229063 hasBestOaLocation W21542290631 @default.
• W2154229063 hasConcept C104317684 @default.
• W2154229063 hasConcept C121608353 @default.
• W2154229063 hasConcept C134018914 @default.
• W2154229063 hasConcept C15729860 @default.
• W2154229063 hasConcept C171056886 @default.
• W2154229063 hasConcept C201750760 @default.
• W2154229063 hasConcept C203014093 @default.
• W2154229063 hasConcept C2778764654 @default.
• W2154229063 hasConcept C2780210213 @default.
• W2154229063 hasConcept C2781187634 @default.
• W2154229063 hasConcept C28328180 @default.
• W2154229063 hasConcept C41091548 @default.
• W2154229063 hasConcept C50171091 @default.
• W2154229063 hasConcept C502942594 @default.
• W2154229063 hasConcept C526805850 @default.
• W2154229063 hasConcept C54355233 @default.
• W2154229063 hasConcept C6929976 @default.
• W2154229063 hasConcept C86803240 @default.
• W2154229063 hasConcept C95444343 @default.
• W2154229063 hasConceptScore W2154229063C104317684 @default.
• W2154229063 hasConceptScore W2154229063C121608353 @default.
• W2154229063 hasConceptScore W2154229063C134018914 @default.
• W2154229063 hasConceptScore W2154229063C15729860 @default.
• W2154229063 hasConceptScore W2154229063C171056886 @default.
• W2154229063 hasConceptScore W2154229063C201750760 @default.
• W2154229063 hasConceptScore W2154229063C203014093 @default.
• W2154229063 hasConceptScore W2154229063C2778764654 @default.
• W2154229063 hasConceptScore W2154229063C2780210213 @default.

• next