FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154231824> ?p ?o ?g. }

• W2154231824 endingPage "2531" @default.
• W2154231824 startingPage "2531" @default.
• W2154231824 abstract "Phase I/II enzymes metabolize environmental carcin-ogens and several functional polymorphisms have been reported in their encoding genes. Although their significance with regard to esophageal carcinogenicity has been examined epidemiologically, it remains controversial. The present systematic review of the literature was performed to clarify associations.Eligible studies were case-control or cohort studies published until September 2004 that were written in any language. From PubMed and a manual review of reference lists in relevant review articles, we obtained 16 studies related to the CYP1A1 Ile-Val substitution in exon 7, CYP1A1 MspI polymorphisms, CYP2E1 RsaI polymorphisms, GSTM1 null type, GSTT1 null type and GSTP1 Ile104Val. All were of case-control design. Summary statistics were odds ratios (ORs) comparing heterozygous-, homozygous-non-wild type or these two in combination with the homozygous wild type, or the null type with the non-null type for GSTM1 and GSTT1. A random effect model was used to estimate the summary ORs. A meta-regression analysis was applied to explore sources of heterogeneity.Individuals with the Ile-Val substitution in CYP1A1 exon 7 had increased esophageal cancer risk, with ORs (95%CI) compared with Ile/Ile of 1.37 (1.09-1.71), 2.52 (1.62-3.91) and 1.44 (1.17-1.78) for Ile-Val, Val/Val genotype and the combined group. No significant association was found between esophageal cancer risk and the other genetic parameters.A significant association exists between the CYP1A1 Ile-Val polymorphism and risk of esophageal cancer. Polymorphisms that increase the internal exposure to activated carcinogens may increase the risk of esophageal cancer." @default.
• W2154231824 created "2016-06-24" @default.
• W2154231824 creator A5000072069 @default.
• W2154231824 creator A5034093082 @default.
• W2154231824 creator A5051132319 @default.
• W2154231824 creator A5072128957 @default.
• W2154231824 date "2005-01-01" @default.
• W2154231824 modified "2023-09-27" @default.
• W2154231824 title "Phase I/II enzyme gene polymorphisms and esophageal cancer risk: A meta-analysis of the literature" @default.
• W2154231824 cites W1496567239 @default.
• W2154231824 cites W1518165131 @default.
• W2154231824 cites W1750764013 @default.
• W2154231824 cites W1971583070 @default.
• W2154231824 cites W1972326852 @default.
• W2154231824 cites W1972655950 @default.
• W2154231824 cites W1980465661 @default.
• W2154231824 cites W1980576851 @default.
• W2154231824 cites W1994695514 @default.
• W2154231824 cites W1995948621 @default.
• W2154231824 cites W2010896476 @default.
• W2154231824 cites W2012810505 @default.
• W2154231824 cites W2021651298 @default.
• W2154231824 cites W2022689643 @default.
• W2154231824 cites W2045712143 @default.
• W2154231824 cites W2057851080 @default.
• W2154231824 cites W2058919729 @default.
• W2154231824 cites W206153150 @default.
• W2154231824 cites W2065964332 @default.
• W2154231824 cites W2072285842 @default.
• W2154231824 cites W2073200608 @default.
• W2154231824 cites W2086368369 @default.
• W2154231824 cites W2091854189 @default.
• W2154231824 cites W2098528905 @default.
• W2154231824 cites W2105639448 @default.
• W2154231824 cites W2108387455 @default.
• W2154231824 cites W2112710602 @default.
• W2154231824 cites W2116431379 @default.
• W2154231824 cites W2120462165 @default.
• W2154231824 cites W2121947346 @default.
• W2154231824 cites W2125275218 @default.
• W2154231824 cites W2125386601 @default.
• W2154231824 cites W2125713856 @default.
• W2154231824 cites W2131133638 @default.
• W2154231824 cites W2132081811 @default.
• W2154231824 cites W2136839357 @default.
• W2154231824 cites W2139458075 @default.
• W2154231824 cites W2139686516 @default.
• W2154231824 cites W2147977885 @default.
• W2154231824 cites W2149982142 @default.
• W2154231824 cites W2150440412 @default.
• W2154231824 cites W2153235080 @default.
• W2154231824 cites W2155975852 @default.
• W2154231824 cites W2161863099 @default.
• W2154231824 cites W2165133953 @default.
• W2154231824 cites W2185449138 @default.
• W2154231824 cites W2188965485 @default.
• W2154231824 cites W2197835777 @default.
• W2154231824 cites W2318048476 @default.
• W2154231824 cites W2371698049 @default.
• W2154231824 cites W2373508770 @default.
• W2154231824 cites W2404968679 @default.
• W2154231824 cites W2414902767 @default.
• W2154231824 cites W2417371054 @default.
• W2154231824 cites W2435508641 @default.
• W2154231824 cites W2746901953 @default.
• W2154231824 cites W4251822584 @default.
• W2154231824 doi "https://doi.org/10.3748/wjg.v11.i17.2531" @default.
• W2154231824 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4305738" @default.
• W2154231824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15849806" @default.
• W2154231824 hasPublicationYear "2005" @default.
• W2154231824 type Work @default.
• W2154231824 sameAs 2154231824 @default.
• W2154231824 citedByCount "75" @default.
• W2154231824 countsByYear W21542318242012 @default.
• W2154231824 countsByYear W21542318242013 @default.
• W2154231824 countsByYear W21542318242014 @default.
• W2154231824 countsByYear W21542318242015 @default.
• W2154231824 countsByYear W21542318242016 @default.
• W2154231824 countsByYear W21542318242018 @default.
• W2154231824 countsByYear W21542318242019 @default.
• W2154231824 countsByYear W21542318242020 @default.
• W2154231824 countsByYear W21542318242022 @default.
• W2154231824 crossrefType "journal-article" @default.
• W2154231824 hasAuthorship W2154231824A5000072069 @default.
• W2154231824 hasAuthorship W2154231824A5034093082 @default.
• W2154231824 hasAuthorship W2154231824A5051132319 @default.
• W2154231824 hasAuthorship W2154231824A5072128957 @default.
• W2154231824 hasBestOaLocation W21542318241 @default.
• W2154231824 hasConcept C104317684 @default.
• W2154231824 hasConcept C121608353 @default.
• W2154231824 hasConcept C126322002 @default.
• W2154231824 hasConcept C135763542 @default.
• W2154231824 hasConcept C143998085 @default.
• W2154231824 hasConcept C146304588 @default.
• W2154231824 hasConcept C156957248 @default.
• W2154231824 hasConcept C2779742542 @default.
• W2154231824 hasConcept C36823959 @default.
• W2154231824 hasConcept C54355233 @default.

• next