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• W2154242091 abstract "DNA cytosine methylation is a central epigenetic modification which plays critical roles in cellular processes including genome regulation, development and disease. Here, we review current and emerging microarray and next-generation sequencing based technologies that enhance our knowledge of DNA methylation profiling. Each methodology has limitations and their unique applications, and combinations of several modalities may help build the entire methylome. With advances on next-generation sequencing technologies, it is now possible to globally map the DNA cytosine methylation at single-base resolution, providing new insights into the regulation and dynamics of DNA methylation in genomes." @default.
• W2154242091 created "2016-06-24" @default.
• W2154242091 creator A5016525715 @default.
• W2154242091 creator A5066786439 @default.
• W2154242091 date "2010-04-01" @default.
• W2154242091 modified "2023-10-10" @default.
• W2154242091 title "Profiling DNA Methylomes from Microarray to Genome-Scale Sequencing" @default.
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• W2154242091 doi "https://doi.org/10.1177/153303461000900203" @default.
• W2154242091 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3011833" @default.
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