FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154243137> ?p ?o ?g. }

• W2154243137 abstract "Patients with bicuspid aortic valve (BAV) may gradually develop significant valve dysfunction, whereas others remain free of dysfunction. Factors that determine the prognosis of BAV remain unclear. Because endothelial progenitor cells (EPCs) have a role in the repair of endothelial surfaces after injury, we hypothesized that EPCs may also be involved in preventing BAV degeneration. Accordingly, we compared EPC level and function in patients with BAV with versus without valve dysfunction. The study group included 22 patients with BAV and significant valve dysfunction (at least moderate aortic regurgitation and/or at least moderate aortic stenosis). The control group included 28 patients with BAV without valve dysfunction. All patients had 1 blood sample taken. Proportion of peripheral mononuclear cells expressing vascular endothelial growth factor receptor 2, CD133 and CD34 was evaluated by flow cytometry. EPC colony-forming units (CFUs) were grown from peripheral mononuclear cells, characterized, and counted after 7 days of culture. The 2 groups had similar clinical characteristics except for higher prevalence of hypertension in the dysfunctional valve group. Number of EPC CFUs was smaller in the dysfunctional valve group (32 CFUs/plate, 15 to 42.5, vs 48 CFUs/plate, 30 to 62.5, respectively, p = 0.01), and the migratory capacity of the cells in this group was decreased. In addition, the proportion of cells coexpressing vascular endothelial growth factor receptor 2, CD133, and CD34 tended to be smaller in the dysfunctional valve group. In conclusion, patients with BAV and significant valve dysfunction appear to have circulating EPCs with impaired functional properties. These findings require validation by further studies." @default.
• W2154243137 created "2016-06-24" @default.
• W2154243137 creator A5008223137 @default.
• W2154243137 creator A5025224955 @default.
• W2154243137 creator A5026973351 @default.
• W2154243137 creator A5027937187 @default.
• W2154243137 creator A5039789130 @default.
• W2154243137 creator A5050858268 @default.
• W2154243137 creator A5073592971 @default.
• W2154243137 creator A5079579563 @default.
• W2154243137 creator A5079635331 @default.
• W2154243137 creator A5081991726 @default.
• W2154243137 creator A5082555622 @default.
• W2154243137 creator A5088013459 @default.
• W2154243137 date "2011-07-01" @default.
• W2154243137 modified "2023-09-27" @default.
• W2154243137 title "Circulating Endothelial Progenitor Cells in Patients With Dysfunctional Versus Normally Functioning Congenitally Bicuspid Aortic Valves" @default.
• W2154243137 cites W1502896205 @default.
• W2154243137 cites W1849785625 @default.
• W2154243137 cites W1970563482 @default.
• W2154243137 cites W1977312306 @default.
• W2154243137 cites W2008018400 @default.
• W2154243137 cites W2022757974 @default.
• W2154243137 cites W2025299174 @default.
• W2154243137 cites W2027359061 @default.
• W2154243137 cites W2038473729 @default.
• W2154243137 cites W2049035024 @default.
• W2154243137 cites W2059941036 @default.
• W2154243137 cites W2084231836 @default.
• W2154243137 cites W2085652180 @default.
• W2154243137 cites W2098743872 @default.
• W2154243137 cites W2103317822 @default.
• W2154243137 cites W2104974378 @default.
• W2154243137 cites W2107730622 @default.
• W2154243137 cites W2107948455 @default.
• W2154243137 cites W2109068464 @default.
• W2154243137 cites W2121165964 @default.
• W2154243137 cites W2127872440 @default.
• W2154243137 cites W2145639716 @default.
• W2154243137 cites W2157214435 @default.
• W2154243137 cites W2160632456 @default.
• W2154243137 cites W2169998579 @default.
• W2154243137 doi "https://doi.org/10.1016/j.amjcard.2011.03.039" @default.
• W2154243137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21550575" @default.
• W2154243137 hasPublicationYear "2011" @default.
• W2154243137 type Work @default.
• W2154243137 sameAs 2154243137 @default.
• W2154243137 citedByCount "20" @default.
• W2154243137 countsByYear W21542431372012 @default.
• W2154243137 countsByYear W21542431372013 @default.
• W2154243137 countsByYear W21542431372014 @default.
• W2154243137 countsByYear W21542431372015 @default.
• W2154243137 countsByYear W21542431372017 @default.
• W2154243137 countsByYear W21542431372019 @default.
• W2154243137 countsByYear W21542431372020 @default.
• W2154243137 countsByYear W21542431372021 @default.
• W2154243137 crossrefType "journal-article" @default.
• W2154243137 hasAuthorship W2154243137A5008223137 @default.
• W2154243137 hasAuthorship W2154243137A5025224955 @default.
• W2154243137 hasAuthorship W2154243137A5026973351 @default.
• W2154243137 hasAuthorship W2154243137A5027937187 @default.
• W2154243137 hasAuthorship W2154243137A5039789130 @default.
• W2154243137 hasAuthorship W2154243137A5050858268 @default.
• W2154243137 hasAuthorship W2154243137A5073592971 @default.
• W2154243137 hasAuthorship W2154243137A5079579563 @default.
• W2154243137 hasAuthorship W2154243137A5079635331 @default.
• W2154243137 hasAuthorship W2154243137A5081991726 @default.
• W2154243137 hasAuthorship W2154243137A5082555622 @default.
• W2154243137 hasAuthorship W2154243137A5088013459 @default.
• W2154243137 hasConcept C10205521 @default.
• W2154243137 hasConcept C126322002 @default.
• W2154243137 hasConcept C164705383 @default.
• W2154243137 hasConcept C201750760 @default.
• W2154243137 hasConcept C27502469 @default.
• W2154243137 hasConcept C2780152582 @default.
• W2154243137 hasConcept C2780714102 @default.
• W2154243137 hasConcept C2780972559 @default.
• W2154243137 hasConcept C2781355080 @default.
• W2154243137 hasConcept C28328180 @default.
• W2154243137 hasConcept C2910672364 @default.
• W2154243137 hasConcept C54355233 @default.
• W2154243137 hasConcept C70410870 @default.
• W2154243137 hasConcept C71924100 @default.
• W2154243137 hasConcept C86803240 @default.
• W2154243137 hasConceptScore W2154243137C10205521 @default.
• W2154243137 hasConceptScore W2154243137C126322002 @default.
• W2154243137 hasConceptScore W2154243137C164705383 @default.
• W2154243137 hasConceptScore W2154243137C201750760 @default.
• W2154243137 hasConceptScore W2154243137C27502469 @default.
• W2154243137 hasConceptScore W2154243137C2780152582 @default.
• W2154243137 hasConceptScore W2154243137C2780714102 @default.
• W2154243137 hasConceptScore W2154243137C2780972559 @default.
• W2154243137 hasConceptScore W2154243137C2781355080 @default.
• W2154243137 hasConceptScore W2154243137C28328180 @default.
• W2154243137 hasConceptScore W2154243137C2910672364 @default.
• W2154243137 hasConceptScore W2154243137C54355233 @default.
• W2154243137 hasConceptScore W2154243137C70410870 @default.
• W2154243137 hasConceptScore W2154243137C71924100 @default.
• W2154243137 hasConceptScore W2154243137C86803240 @default.
• W2154243137 hasLocation W21542431371 @default.

• next