Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154298208> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2154298208 endingPage "466" @default.
- W2154298208 startingPage "449" @default.
- W2154298208 abstract "Using four common mutagens, ethyl methanesulphonate (EMS), methyl methanesulphonate (MMS), UV, and X-irradiation, the relationship between dose of mutagen, cellular lethality and frequency of 8-azaguanine resistant colonies in V79 Chinese hamster cells has been examined. Several factors affecting the recovery of mutants including inter and intra-clone metabolic co-operation have been quantitated and their influence on survival response curves examined. Induced mutant frequencies were assayed by two methods in situ, and after replating. After exposure to X-rays, MMS and UV a significantly higher frequency of mutants was observed in replated experiments as compared with the in situ situation, at all survival levels assayed. With EMS, an increment on replating was observed only at high survival levels. The replating data suggest that two types of azgr colonies are produced, i.e. those which contain only azgr cells and those which, due to damage segregation, contain a mixture of azgr and azgs cells. These mixed colonies appear to be lost by metabolic co-operation when mutation frequencies are assayed in situ. The proportion of mixed to homogeneous colonies differs with different mutagens. Taking into account such factors, EMS and UV irradiation were similarly mutagenic at a given survival level, but at equitoxic doses, fewer mutants were recovered after exposure of V79 cells to MMS and X-rays." @default.
- W2154298208 created "2016-06-24" @default.
- W2154298208 creator A5043517746 @default.
- W2154298208 date "1975-09-01" @default.
- W2154298208 modified "2023-10-15" @default.
- W2154298208 title "Factors affecting the quantitation of dose-response curves for mutation induction in V79 Chinese hamster cells after exposure to chemical and physical mutagens" @default.
- W2154298208 cites W1966941509 @default.
- W2154298208 cites W1975909701 @default.
- W2154298208 cites W1995414715 @default.
- W2154298208 cites W2025585188 @default.
- W2154298208 cites W2037311904 @default.
- W2154298208 cites W2038694894 @default.
- W2154298208 cites W2038795463 @default.
- W2154298208 cites W2056213352 @default.
- W2154298208 cites W2059271633 @default.
- W2154298208 cites W2102254499 @default.
- W2154298208 cites W2111166201 @default.
- W2154298208 cites W2121233435 @default.
- W2154298208 cites W4299521229 @default.
- W2154298208 doi "https://doi.org/10.1016/0027-5107(75)90064-0" @default.
- W2154298208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1177958" @default.
- W2154298208 hasPublicationYear "1975" @default.
- W2154298208 type Work @default.
- W2154298208 sameAs 2154298208 @default.
- W2154298208 citedByCount "54" @default.
- W2154298208 crossrefType "journal-article" @default.
- W2154298208 hasAuthorship W2154298208A5043517746 @default.
- W2154298208 hasConcept C102306862 @default.
- W2154298208 hasConcept C104317684 @default.
- W2154298208 hasConcept C114246631 @default.
- W2154298208 hasConcept C141710004 @default.
- W2154298208 hasConcept C143065580 @default.
- W2154298208 hasConcept C153911025 @default.
- W2154298208 hasConcept C16318435 @default.
- W2154298208 hasConcept C175656101 @default.
- W2154298208 hasConcept C178790620 @default.
- W2154298208 hasConcept C185592680 @default.
- W2154298208 hasConcept C2776639595 @default.
- W2154298208 hasConcept C2777755551 @default.
- W2154298208 hasConcept C2778575167 @default.
- W2154298208 hasConcept C2778959862 @default.
- W2154298208 hasConcept C2779115727 @default.
- W2154298208 hasConcept C29730261 @default.
- W2154298208 hasConcept C33070731 @default.
- W2154298208 hasConcept C501734568 @default.
- W2154298208 hasConcept C54355233 @default.
- W2154298208 hasConcept C552990157 @default.
- W2154298208 hasConcept C81089528 @default.
- W2154298208 hasConcept C81885089 @default.
- W2154298208 hasConcept C86803240 @default.
- W2154298208 hasConceptScore W2154298208C102306862 @default.
- W2154298208 hasConceptScore W2154298208C104317684 @default.
- W2154298208 hasConceptScore W2154298208C114246631 @default.
- W2154298208 hasConceptScore W2154298208C141710004 @default.
- W2154298208 hasConceptScore W2154298208C143065580 @default.
- W2154298208 hasConceptScore W2154298208C153911025 @default.
- W2154298208 hasConceptScore W2154298208C16318435 @default.
- W2154298208 hasConceptScore W2154298208C175656101 @default.
- W2154298208 hasConceptScore W2154298208C178790620 @default.
- W2154298208 hasConceptScore W2154298208C185592680 @default.
- W2154298208 hasConceptScore W2154298208C2776639595 @default.
- W2154298208 hasConceptScore W2154298208C2777755551 @default.
- W2154298208 hasConceptScore W2154298208C2778575167 @default.
- W2154298208 hasConceptScore W2154298208C2778959862 @default.
- W2154298208 hasConceptScore W2154298208C2779115727 @default.
- W2154298208 hasConceptScore W2154298208C29730261 @default.
- W2154298208 hasConceptScore W2154298208C33070731 @default.
- W2154298208 hasConceptScore W2154298208C501734568 @default.
- W2154298208 hasConceptScore W2154298208C54355233 @default.
- W2154298208 hasConceptScore W2154298208C552990157 @default.
- W2154298208 hasConceptScore W2154298208C81089528 @default.
- W2154298208 hasConceptScore W2154298208C81885089 @default.
- W2154298208 hasConceptScore W2154298208C86803240 @default.
- W2154298208 hasIssue "3" @default.
- W2154298208 hasLocation W21542982081 @default.
- W2154298208 hasLocation W21542982082 @default.
- W2154298208 hasOpenAccess W2154298208 @default.
- W2154298208 hasPrimaryLocation W21542982081 @default.
- W2154298208 hasRelatedWork W1969505668 @default.
- W2154298208 hasRelatedWork W1970240908 @default.
- W2154298208 hasRelatedWork W2007253861 @default.
- W2154298208 hasRelatedWork W2017862149 @default.
- W2154298208 hasRelatedWork W2029585401 @default.
- W2154298208 hasRelatedWork W2047901236 @default.
- W2154298208 hasRelatedWork W2065120809 @default.
- W2154298208 hasRelatedWork W2112663183 @default.
- W2154298208 hasRelatedWork W2153422873 @default.
- W2154298208 hasRelatedWork W2411584148 @default.
- W2154298208 hasVolume "29" @default.
- W2154298208 isParatext "false" @default.
- W2154298208 isRetracted "false" @default.
- W2154298208 magId "2154298208" @default.
- W2154298208 workType "article" @default.