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- W2154299504 abstract "Statins have been shown to inhibit oxidative stress, however it is still unclear if they influence antioxidant status. We performed a retrospective analysis of oxidative stress, as assessed by serum levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and vitamin E, a known antioxidant, in patients with metabolic syndrome (n=112) treated (n=30) or not (n=82) with statins. Statin-treated patients showed higher levels of vitamin E (p=0.02) and lower 8-OHdG (p<0.01) than statin-free patients. An inverse correlation between oxidative stress and vitamin E was observed (r=−0.670, p<0.001). These preliminary data suggest that statins enhance the antioxidant status likely by inhibiting oxidative stress." @default.
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- W2154299504 date "2008-01-01" @default.
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- W2154299504 title "Statins enhance circulating vitamin E" @default.
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- W2154299504 doi "https://doi.org/10.1016/j.ijcard.2006.11.115" @default.
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