FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154320911> ?p ?o ?g. }

• W2154320911 endingPage "21" @default.
• W2154320911 startingPage "11" @default.
• W2154320911 abstract "We have isolated and characterized a unique glial-restricted precursor cell (GRP) from the embryonic spinal cord. Clonal analysis demonstrated that these cells are able to generate oligodendrocytes and two distinct type of astrocytes (type 1 and type 2) when exposed to appropriate signals in vitro. We now show that many aspects of these cells are retained in vivo. GRP cells are restricted to the glial lineage in vivo as they seem to be unable to generate neuronal phenotypes in an in vivo neurogenic environment. GRP cells survive and migrate in the neonatal and adult brain. Transplanted GRP cells differentiate into myelin-forming oligodendrocytes in a myelin-deficient background and also generate immature oligodendrocytes in the normal neonatal brain. In addition, GRP cells also consistently generated glial fibrillary protein-expressing cells in the neonatal and adult brain, a property not consistently expressed by other glial precursor cells like the O-2A/OPC cells. We suggest that the lineage restriction of GRP cells and their ability to generate both oligodendrocytes and astrocytes in vivo together with their embryonic character that allows for extensive in vitro expansion of the population makes the cell useful for clinical application." @default.
• W2154320911 created "2016-06-24" @default.
• W2154320911 creator A5004568167 @default.
• W2154320911 creator A5006389683 @default.
• W2154320911 creator A5010504185 @default.
• W2154320911 creator A5020042704 @default.
• W2154320911 creator A5032263061 @default.
• W2154320911 creator A5034344782 @default.
• W2154320911 creator A5046708795 @default.
• W2154320911 creator A5077270806 @default.
• W2154320911 date "2001-09-01" @default.
• W2154320911 modified "2023-10-08" @default.
• W2154320911 title "Embryonic-Derived Glial-Restricted Precursor Cells (GRP Cells) Can Differentiate into Astrocytes and Oligodendrocytes in Vivo" @default.
• W2154320911 cites W1483007837 @default.
• W2154320911 cites W1503241134 @default.
• W2154320911 cites W1520104311 @default.
• W2154320911 cites W1837402303 @default.
• W2154320911 cites W1924903894 @default.
• W2154320911 cites W1929292180 @default.
• W2154320911 cites W1968019641 @default.
• W2154320911 cites W1972524334 @default.
• W2154320911 cites W1973972775 @default.
• W2154320911 cites W1975366872 @default.
• W2154320911 cites W1978398040 @default.
• W2154320911 cites W1986354733 @default.
• W2154320911 cites W1995953095 @default.
• W2154320911 cites W1998502499 @default.
• W2154320911 cites W1998931558 @default.
• W2154320911 cites W2002066403 @default.
• W2154320911 cites W2003059404 @default.
• W2154320911 cites W2003735806 @default.
• W2154320911 cites W2004588076 @default.
• W2154320911 cites W2007202464 @default.
• W2154320911 cites W2009537058 @default.
• W2154320911 cites W2013152746 @default.
• W2154320911 cites W2023587253 @default.
• W2154320911 cites W2024825981 @default.
• W2154320911 cites W2025048899 @default.
• W2154320911 cites W2026599973 @default.
• W2154320911 cites W2026627501 @default.
• W2154320911 cites W2035199397 @default.
• W2154320911 cites W2040635309 @default.
• W2154320911 cites W2045286159 @default.
• W2154320911 cites W2049544176 @default.
• W2154320911 cites W2051750808 @default.
• W2154320911 cites W2056164362 @default.
• W2154320911 cites W2060885134 @default.
• W2154320911 cites W2064905483 @default.
• W2154320911 cites W2067198472 @default.
• W2154320911 cites W2074924223 @default.
• W2154320911 cites W2075590101 @default.
• W2154320911 cites W2076957088 @default.
• W2154320911 cites W2084761937 @default.
• W2154320911 cites W2113964043 @default.
• W2154320911 cites W2120474496 @default.
• W2154320911 cites W2137605614 @default.
• W2154320911 cites W2144762351 @default.
• W2154320911 cites W2158810132 @default.
• W2154320911 cites W2159120052 @default.
• W2154320911 cites W2161432891 @default.
• W2154320911 cites W2167659174 @default.
• W2154320911 cites W4237567990 @default.
• W2154320911 doi "https://doi.org/10.1006/exnr.2001.7729" @default.
• W2154320911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11520117" @default.
• W2154320911 hasPublicationYear "2001" @default.
• W2154320911 type Work @default.
• W2154320911 sameAs 2154320911 @default.
• W2154320911 citedByCount "89" @default.
• W2154320911 countsByYear W21543209112012 @default.
• W2154320911 countsByYear W21543209112013 @default.
• W2154320911 countsByYear W21543209112014 @default.
• W2154320911 countsByYear W21543209112015 @default.
• W2154320911 countsByYear W21543209112016 @default.
• W2154320911 countsByYear W21543209112017 @default.
• W2154320911 countsByYear W21543209112018 @default.
• W2154320911 countsByYear W21543209112019 @default.
• W2154320911 countsByYear W21543209112020 @default.
• W2154320911 countsByYear W21543209112021 @default.
• W2154320911 countsByYear W21543209112022 @default.
• W2154320911 countsByYear W21543209112023 @default.
• W2154320911 crossrefType "journal-article" @default.
• W2154320911 hasAuthorship W2154320911A5004568167 @default.
• W2154320911 hasAuthorship W2154320911A5006389683 @default.
• W2154320911 hasAuthorship W2154320911A5010504185 @default.
• W2154320911 hasAuthorship W2154320911A5020042704 @default.
• W2154320911 hasAuthorship W2154320911A5032263061 @default.
• W2154320911 hasAuthorship W2154320911A5034344782 @default.
• W2154320911 hasAuthorship W2154320911A5046708795 @default.
• W2154320911 hasAuthorship W2154320911A5077270806 @default.
• W2154320911 hasConcept C104317684 @default.
• W2154320911 hasConcept C124964019 @default.
• W2154320911 hasConcept C145103041 @default.
• W2154320911 hasConcept C162746124 @default.
• W2154320911 hasConcept C169760540 @default.
• W2154320911 hasConcept C202751555 @default.
• W2154320911 hasConcept C203014093 @default.
• W2154320911 hasConcept C204232928 @default.
• W2154320911 hasConcept C207001950 @default.

• next