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• W2154332398 abstract "Optical probe methods for in vivo assessments of cutaneous photoaging are necessary in fields such as anti-aging dermatology and skin cosmetic development. We investigated the relation between wrinkle direction and collagen orientation in ultraviolet-B-exposed (UVB-exposed) skin using polarization-resolved second-harmonic-generation (SHG) microscopy. A polarization anisotropic image of the SHG light indicated that wrinkle direction in UVB-exposed skin is predominantly parallel to the orientation of dermal collagen fibers. Furthermore, collagen orientation in post-UVB-exposed skin with few wrinkles changed from that of UVB-exposed wrinkled skin to that of no-UVB-exposed skin. The method proposed has the potential to become a powerful non-invasive tool for assessment of cutaneous photoaging." @default.
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• W2154332398 date "2009-01-12" @default.
• W2154332398 modified "2023-10-05" @default.
• W2154332398 title "Observation of dermal collagen fiber in wrinkled skin using polarization-resolved second-harmonic-generation microscopy" @default.
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• W2154332398 doi "https://doi.org/10.1364/oe.17.000912" @default.
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