Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154372156> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2154372156 endingPage "195" @default.
- W2154372156 startingPage "185" @default.
- W2154372156 abstract "The diagnosis of coronary artery disease (CAD) is an important task in the management of cardiology patients. Recently, the use of pharmacological stress testing has become available as an alternative to exercise stress testing (ETT). A new system (device-drug combination) was developed specifically for the diagnosis of coronary artery disease. The system uses a novel catecholamine, arbutamine, which is infused intravenously to increase heart rate (HR) and cardiac contractility in order to evoke signs of ischemia. The development of a closed-loop control algorithm for the delivery of this drug and a pharmacodynamic (PD) model representing the HR response to arbutamine infusions are presented. Model parameters are estimated from clinical data on normal volunteers and patients. Based on this mathematical model, a rule-based control algorithm is designed. The structure of the control algorithm is discussed and testing of the algorithm based on simulations and animal and human trials are summarized. Results from clinical trials shows that the algorithm controls the HR increase according to a selected trajectory. The automated delivery of the drug can provide the cardiologist with an efficient, effective, and safe method for administering a pharmacological stress test." @default.
- W2154372156 created "2016-06-24" @default.
- W2154372156 creator A5040976819 @default.
- W2154372156 creator A5079984254 @default.
- W2154372156 date "1997-03-01" @default.
- W2154372156 modified "2023-09-27" @default.
- W2154372156 title "Closed-loop drug infusion for control of heart-rate trajectory in pharmacological stress tests" @default.
- W2154372156 cites W1965324089 @default.
- W2154372156 cites W2025555967 @default.
- W2154372156 cites W2026694904 @default.
- W2154372156 cites W2033854491 @default.
- W2154372156 cites W2035482081 @default.
- W2154372156 cites W2048355400 @default.
- W2154372156 cites W2050231964 @default.
- W2154372156 cites W2092851604 @default.
- W2154372156 cites W2119918525 @default.
- W2154372156 cites W2153476681 @default.
- W2154372156 cites W2159338597 @default.
- W2154372156 cites W2161649667 @default.
- W2154372156 cites W2164271842 @default.
- W2154372156 cites W167067906 @default.
- W2154372156 cites W2419058542 @default.
- W2154372156 doi "https://doi.org/10.1109/10.554765" @default.
- W2154372156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9216132" @default.
- W2154372156 hasPublicationYear "1997" @default.
- W2154372156 type Work @default.
- W2154372156 sameAs 2154372156 @default.
- W2154372156 citedByCount "19" @default.
- W2154372156 countsByYear W21543721562012 @default.
- W2154372156 countsByYear W21543721562013 @default.
- W2154372156 countsByYear W21543721562016 @default.
- W2154372156 countsByYear W21543721562019 @default.
- W2154372156 countsByYear W21543721562021 @default.
- W2154372156 crossrefType "journal-article" @default.
- W2154372156 hasAuthorship W2154372156A5040976819 @default.
- W2154372156 hasAuthorship W2154372156A5079984254 @default.
- W2154372156 hasConcept C126322002 @default.
- W2154372156 hasConcept C164705383 @default.
- W2154372156 hasConcept C199360897 @default.
- W2154372156 hasConcept C2777953023 @default.
- W2154372156 hasConcept C2778213512 @default.
- W2154372156 hasConcept C2780035454 @default.
- W2154372156 hasConcept C39133596 @default.
- W2154372156 hasConcept C41008148 @default.
- W2154372156 hasConcept C71924100 @default.
- W2154372156 hasConcept C7515471 @default.
- W2154372156 hasConcept C84393581 @default.
- W2154372156 hasConcept C98274493 @default.
- W2154372156 hasConceptScore W2154372156C126322002 @default.
- W2154372156 hasConceptScore W2154372156C164705383 @default.
- W2154372156 hasConceptScore W2154372156C199360897 @default.
- W2154372156 hasConceptScore W2154372156C2777953023 @default.
- W2154372156 hasConceptScore W2154372156C2778213512 @default.
- W2154372156 hasConceptScore W2154372156C2780035454 @default.
- W2154372156 hasConceptScore W2154372156C39133596 @default.
- W2154372156 hasConceptScore W2154372156C41008148 @default.
- W2154372156 hasConceptScore W2154372156C71924100 @default.
- W2154372156 hasConceptScore W2154372156C7515471 @default.
- W2154372156 hasConceptScore W2154372156C84393581 @default.
- W2154372156 hasConceptScore W2154372156C98274493 @default.
- W2154372156 hasIssue "3" @default.
- W2154372156 hasLocation W21543721561 @default.
- W2154372156 hasLocation W21543721562 @default.
- W2154372156 hasOpenAccess W2154372156 @default.
- W2154372156 hasPrimaryLocation W21543721561 @default.
- W2154372156 hasRelatedWork W1993721318 @default.
- W2154372156 hasRelatedWork W2119625140 @default.
- W2154372156 hasRelatedWork W2121565664 @default.
- W2154372156 hasRelatedWork W2153622558 @default.
- W2154372156 hasRelatedWork W2159512267 @default.
- W2154372156 hasRelatedWork W2410513801 @default.
- W2154372156 hasRelatedWork W2417414779 @default.
- W2154372156 hasRelatedWork W2418852743 @default.
- W2154372156 hasRelatedWork W2896996553 @default.
- W2154372156 hasRelatedWork W3011902026 @default.
- W2154372156 hasVolume "44" @default.
- W2154372156 isParatext "false" @default.
- W2154372156 isRetracted "false" @default.
- W2154372156 magId "2154372156" @default.
- W2154372156 workType "article" @default.