FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154454692> ?p ?o ?g. }

• W2154454692 endingPage "1210" @default.
• W2154454692 startingPage "1204" @default.
• W2154454692 abstract "Objectives were to examine possible roles of estrogen receptor (ER) in development of the bovine uterine endometrium in the context of ER type, enhancer type, and ligand-independent activation. Expression vectors producing either ERalpha or ERbeta were introduced into fetal uterine cells from Day 110 to 120 of gestation (UBF120 cells) and into rat embryo fibroblasts (Rat-1 cells), neither of which express endogenous ER. Reporter constructs containing either an estrogen response element (ERE) or activator protein-1 (AP-1) response element were cotransfected. These reporters were also transfected into fetal uterine cells from Day 180 to 200 of gestation (UBF180 cells), which express ER. In UBF120 and Rat-1 cells transfected with either ERalpha or ERbeta, treatment with estradiol-17beta (E2) resulted in increased activity of an ERE reporter construct, but not an AP-1 element reporter construct. The antiestrogen ICI 182,780 (ICI) exhibited E2 antagonist activity with both ERalpha and ERbeta. Thus, all components were present for E2-dependent transcription from an ERE except ER; however, cells were not competent for E2-dependent transcription mediated through AP-1. In UBF180 cells, E2 treatment increased both ERE and AP-1 reporter activity. ICI exhibited E2 antagonist activity. Treatment with epidermal growth factor resulted in increased ERE reporter activity that was inhibited by ICI, indicative of ligand-independent activation of ER. These data suggest that multiple pathways for ER-mediated gene regulation occur in the developing fetal uterus and that nuclear components necessary for action of both ERalpha and ERbeta are present prior to expression of the receptor." @default.
• W2154454692 created "2016-06-24" @default.
• W2154454692 creator A5004302315 @default.
• W2154454692 creator A5053815641 @default.
• W2154454692 creator A5064586833 @default.
• W2154454692 date "1999-05-01" @default.
• W2154454692 modified "2023-09-27" @default.
• W2154454692 title "Estrogen Responses in Bovine Fetal Uterine Cells Involve Pathways Directed by Both Estrogen Response Element and Activator Protein-11" @default.
• W2154454692 cites W1497990622 @default.
• W2154454692 cites W1516164170 @default.
• W2154454692 cites W1520299947 @default.
• W2154454692 cites W1560420809 @default.
• W2154454692 cites W1562960938 @default.
• W2154454692 cites W1646199134 @default.
• W2154454692 cites W1966693149 @default.
• W2154454692 cites W1979801990 @default.
• W2154454692 cites W1982474381 @default.
• W2154454692 cites W1982598173 @default.
• W2154454692 cites W1984151469 @default.
• W2154454692 cites W1990135666 @default.
• W2154454692 cites W1992502560 @default.
• W2154454692 cites W2007889656 @default.
• W2154454692 cites W2008496640 @default.
• W2154454692 cites W2012209524 @default.
• W2154454692 cites W2018159828 @default.
• W2154454692 cites W2023016547 @default.
• W2154454692 cites W2055043387 @default.
• W2154454692 cites W2060903877 @default.
• W2154454692 cites W2068113812 @default.
• W2154454692 cites W2072242719 @default.
• W2154454692 cites W2072787342 @default.
• W2154454692 cites W2073353512 @default.
• W2154454692 cites W2073883348 @default.
• W2154454692 cites W2075957902 @default.
• W2154454692 cites W2081501399 @default.
• W2154454692 cites W2085124463 @default.
• W2154454692 cites W2088002379 @default.
• W2154454692 cites W2095390999 @default.
• W2154454692 cites W2112966757 @default.
• W2154454692 cites W2141269411 @default.
• W2154454692 cites W2147427274 @default.
• W2154454692 cites W2161492813 @default.
• W2154454692 cites W2161623422 @default.
• W2154454692 cites W2321613759 @default.
• W2154454692 cites W2500325312 @default.
• W2154454692 cites W35215362 @default.
• W2154454692 cites W4212936275 @default.
• W2154454692 cites W4229842243 @default.
• W2154454692 cites W2083341348 @default.
• W2154454692 doi "https://doi.org/10.1095/biolreprod60.5.1204" @default.
• W2154454692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10208985" @default.
• W2154454692 hasPublicationYear "1999" @default.
• W2154454692 type Work @default.
• W2154454692 sameAs 2154454692 @default.
• W2154454692 citedByCount "11" @default.
• W2154454692 countsByYear W21544546922022 @default.
• W2154454692 crossrefType "journal-article" @default.
• W2154454692 hasAuthorship W2154454692A5004302315 @default.
• W2154454692 hasAuthorship W2154454692A5053815641 @default.
• W2154454692 hasAuthorship W2154454692A5064586833 @default.
• W2154454692 hasConcept C101762097 @default.
• W2154454692 hasConcept C104317684 @default.
• W2154454692 hasConcept C121608353 @default.
• W2154454692 hasConcept C126322002 @default.
• W2154454692 hasConcept C132376346 @default.
• W2154454692 hasConcept C134018914 @default.
• W2154454692 hasConcept C150194340 @default.
• W2154454692 hasConcept C161733203 @default.
• W2154454692 hasConcept C170493617 @default.
• W2154454692 hasConcept C172313692 @default.
• W2154454692 hasConcept C2777164284 @default.
• W2154454692 hasConcept C51445715 @default.
• W2154454692 hasConcept C530470458 @default.
• W2154454692 hasConcept C54009773 @default.
• W2154454692 hasConcept C54355233 @default.
• W2154454692 hasConcept C55493867 @default.
• W2154454692 hasConcept C71924100 @default.
• W2154454692 hasConcept C81885089 @default.
• W2154454692 hasConcept C84606932 @default.
• W2154454692 hasConcept C86803240 @default.
• W2154454692 hasConcept C88045685 @default.
• W2154454692 hasConcept C96307122 @default.
• W2154454692 hasConceptScore W2154454692C101762097 @default.
• W2154454692 hasConceptScore W2154454692C104317684 @default.
• W2154454692 hasConceptScore W2154454692C121608353 @default.
• W2154454692 hasConceptScore W2154454692C126322002 @default.
• W2154454692 hasConceptScore W2154454692C132376346 @default.
• W2154454692 hasConceptScore W2154454692C134018914 @default.
• W2154454692 hasConceptScore W2154454692C150194340 @default.
• W2154454692 hasConceptScore W2154454692C161733203 @default.
• W2154454692 hasConceptScore W2154454692C170493617 @default.
• W2154454692 hasConceptScore W2154454692C172313692 @default.
• W2154454692 hasConceptScore W2154454692C2777164284 @default.
• W2154454692 hasConceptScore W2154454692C51445715 @default.
• W2154454692 hasConceptScore W2154454692C530470458 @default.
• W2154454692 hasConceptScore W2154454692C54009773 @default.
• W2154454692 hasConceptScore W2154454692C54355233 @default.
• W2154454692 hasConceptScore W2154454692C55493867 @default.

• next