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- W2154458038 endingPage "139" @default.
- W2154458038 startingPage "127" @default.
- W2154458038 abstract "Food reward, not hunger, is the main driving force behind eating in the modern obesogenic environment. Palatable foods, generally calorie-dense and rich in sugar/fat, are thus readily overconsumed despite the resulting health consequences. Important advances have been made to explain mechanisms underlying excessive consumption as an immediate response to presentation of rewarding tastants. However, our understanding of long-term neural adaptations to food reward that oftentimes persist during even a prolonged absence of palatable food and contribute to the reinstatement of compulsive overeating of high-fat high-sugar diets, is much more limited. Here we discuss the evidence from animal and human studies for neural and molecular adaptations in both homeostatic and non-homeostatic appetite regulation that may underlie the formation of a feed-forward system, sensitive to palatable food and propelling the individual from a basic preference for palatable diets to food craving and compulsive, addiction-like eating behavior." @default.
- W2154458038 created "2016-06-24" @default.
- W2154458038 creator A5039005727 @default.
- W2154458038 creator A5055375727 @default.
- W2154458038 creator A5073290917 @default.
- W2154458038 creator A5085396890 @default.
- W2154458038 date "2012-04-01" @default.
- W2154458038 modified "2023-09-22" @default.
- W2154458038 title "Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating" @default.
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