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- W2154485770 abstract "The reaction of an azetidine with a chloroformate can give either the dealkylated heterocycle or the ring-opened product (γ-chloroamine), which can further cyclize to the oxazinanone. A general study of this underrated reaction was conducted and revealed that azetidines can undergo smooth nucleophilic ring-opening reactions to highly functionalized γ-chloroamines in the presence of a variety of alkyl chloroformates under mild reaction conditions. Yields are usually good, and parameters governing this reaction were evaluated." @default.
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- W2154485770 date "2006-11-01" @default.
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- W2154485770 title "Reaction of Azetidines with Chloroformates" @default.
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- W2154485770 doi "https://doi.org/10.1021/ol062128c" @default.
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