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- W2154524434 abstract "A practical sequence for the synthesis of optically active heteroaryl α-(hydroxyamino) esters was explored. The highly diastereoselective addition of heteroaromatics to a cyclic chiral nitrone allowed access to a series of heteroaryl hydroxylamines. The scope of this reaction was evaluated on substrates possessing a pyrrole, an indole, or a furan core. The three-step sequence afforded the α-(hydroxyamino) esters in good overall yields (36–62 %) with good enantiomeric excess values (76 to ≥98 %)." @default.
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- W2154524434 date "2014-05-13" @default.
- W2154524434 modified "2023-10-18" @default.
- W2154524434 title "Concise Preparation of Optically Active Heteroaryl α-(Hydroxyamino) Esters" @default.
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- W2154524434 doi "https://doi.org/10.1002/ejoc.201402322" @default.
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