FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154685763> ?p ?o ?g. }

• W2154685763 endingPage "1374" @default.
• W2154685763 startingPage "1369" @default.
• W2154685763 abstract "What is the effect of FSHB-211G>T together with the FSHR 2039 A>G on serum FSH in women?Serum FSH levels are affected by the combination of genetic polymorphisms in FSHR and FSHB.The relationship between SNPs of the FSHR gene and serum FSH has not been completely clarified. Genetic variants of the FSHB gene have been associated with variation in gene transcription and serum FSH levels in men. No data have been published on the effect of the FSHB-211G>T in women, alone or in combination with the FSHR 2039 A>G.This study was a prospective study including 193 healthy women of reproductive age.Infertile and otherwise healthy eumenorrheic women (n = 193) with normal BMI and serum FSH levels were recruited for the study. In all women early follicular phase FSH and AMH were measured by commercial assays, and antral follicle count was measured by transvaginal ultrasound. Genomic DNA was purified from total peripheral blood and genotyping for the two SNPs was performed.No significant gradients of increasing or decreasing Day 3 FSH across the FSHR 2039 (AA/AG/GG) and FSHB-211 (GG/GT/TT) genotypes, respectively, were observed. When women were stratified according to the FSHR 2039, and FSHB-211 genotypes a statistically significant reduction of d3 FSH was shown in the group of women with the FSHB-211 GT + TT/FSHR2039 AA genotype compared with the FSHB-211 GG/FSHR2039 GG genotype, hence confirming a possible additive effect of the different SNPs in FSHR and FSHB on regulating serum FSH.This finding requires an independent confirmation. However, it confirms the relationship between serum FSH and FSHB together with FSHR gene polymorphisms already reported in males.The knowledge of the FSHB/FSHR genotype combination is fundamental for the proper interpretation of serum FSH levels in women of reproductive age.Merck Serono supported the study in the form of a research grant for the laboratory session. None of the authors have any competing interest to declare." @default.
• W2154685763 created "2016-06-24" @default.
• W2154685763 creator A5004286520 @default.
• W2154685763 creator A5009785362 @default.
• W2154685763 creator A5012757437 @default.
• W2154685763 creator A5016785563 @default.
• W2154685763 creator A5037946770 @default.
• W2154685763 creator A5039654830 @default.
• W2154685763 creator A5046099565 @default.
• W2154685763 creator A5050767535 @default.
• W2154685763 creator A5061175291 @default.
• W2154685763 creator A5074676556 @default.
• W2154685763 creator A5077242442 @default.
• W2154685763 creator A5089212670 @default.
• W2154685763 date "2013-03-15" @default.
• W2154685763 modified "2023-10-16" @default.
• W2154685763 title "The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age" @default.
• W2154685763 cites W1997539759 @default.
• W2154685763 cites W2005271852 @default.
• W2154685763 cites W2023369065 @default.
• W2154685763 cites W2030490673 @default.
• W2154685763 cites W2033116957 @default.
• W2154685763 cites W2053547026 @default.
• W2154685763 cites W2080700340 @default.
• W2154685763 cites W2095294625 @default.
• W2154685763 cites W2109621695 @default.
• W2154685763 cites W2110119053 @default.
• W2154685763 cites W2114110535 @default.
• W2154685763 cites W2118946077 @default.
• W2154685763 cites W2123341694 @default.
• W2154685763 cites W2140486768 @default.
• W2154685763 cites W2142107400 @default.
• W2154685763 cites W2170505179 @default.
• W2154685763 cites W4252219053 @default.
• W2154685763 doi "https://doi.org/10.1093/humrep/det061" @default.
• W2154685763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23504007" @default.
• W2154685763 hasPublicationYear "2013" @default.
• W2154685763 type Work @default.
• W2154685763 sameAs 2154685763 @default.
• W2154685763 citedByCount "50" @default.
• W2154685763 countsByYear W21546857632013 @default.
• W2154685763 countsByYear W21546857632014 @default.
• W2154685763 countsByYear W21546857632015 @default.
• W2154685763 countsByYear W21546857632016 @default.
• W2154685763 countsByYear W21546857632017 @default.
• W2154685763 countsByYear W21546857632018 @default.
• W2154685763 countsByYear W21546857632019 @default.
• W2154685763 countsByYear W21546857632020 @default.
• W2154685763 countsByYear W21546857632021 @default.
• W2154685763 countsByYear W21546857632022 @default.
• W2154685763 countsByYear W21546857632023 @default.
• W2154685763 crossrefType "journal-article" @default.
• W2154685763 hasAuthorship W2154685763A5004286520 @default.
• W2154685763 hasAuthorship W2154685763A5009785362 @default.
• W2154685763 hasAuthorship W2154685763A5012757437 @default.
• W2154685763 hasAuthorship W2154685763A5016785563 @default.
• W2154685763 hasAuthorship W2154685763A5037946770 @default.
• W2154685763 hasAuthorship W2154685763A5039654830 @default.
• W2154685763 hasAuthorship W2154685763A5046099565 @default.
• W2154685763 hasAuthorship W2154685763A5050767535 @default.
• W2154685763 hasAuthorship W2154685763A5061175291 @default.
• W2154685763 hasAuthorship W2154685763A5074676556 @default.
• W2154685763 hasAuthorship W2154685763A5077242442 @default.
• W2154685763 hasAuthorship W2154685763A5089212670 @default.
• W2154685763 hasBestOaLocation W21546857631 @default.
• W2154685763 hasConcept C104317684 @default.
• W2154685763 hasConcept C126322002 @default.
• W2154685763 hasConcept C134018914 @default.
• W2154685763 hasConcept C135763542 @default.
• W2154685763 hasConcept C153209595 @default.
• W2154685763 hasConcept C2778575703 @default.
• W2154685763 hasConcept C2779279165 @default.
• W2154685763 hasConcept C31467283 @default.
• W2154685763 hasConcept C54355233 @default.
• W2154685763 hasConcept C71315377 @default.
• W2154685763 hasConcept C71924100 @default.
• W2154685763 hasConcept C86803240 @default.
• W2154685763 hasConceptScore W2154685763C104317684 @default.
• W2154685763 hasConceptScore W2154685763C126322002 @default.
• W2154685763 hasConceptScore W2154685763C134018914 @default.
• W2154685763 hasConceptScore W2154685763C135763542 @default.
• W2154685763 hasConceptScore W2154685763C153209595 @default.
• W2154685763 hasConceptScore W2154685763C2778575703 @default.
• W2154685763 hasConceptScore W2154685763C2779279165 @default.
• W2154685763 hasConceptScore W2154685763C31467283 @default.
• W2154685763 hasConceptScore W2154685763C54355233 @default.
• W2154685763 hasConceptScore W2154685763C71315377 @default.
• W2154685763 hasConceptScore W2154685763C71924100 @default.
• W2154685763 hasConceptScore W2154685763C86803240 @default.
• W2154685763 hasIssue "5" @default.
• W2154685763 hasLocation W21546857631 @default.
• W2154685763 hasLocation W21546857632 @default.
• W2154685763 hasOpenAccess W2154685763 @default.
• W2154685763 hasPrimaryLocation W21546857631 @default.
• W2154685763 hasRelatedWork W1972504921 @default.
• W2154685763 hasRelatedWork W2013753219 @default.
• W2154685763 hasRelatedWork W2052998204 @default.
• W2154685763 hasRelatedWork W2064034534 @default.

• next