FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154816471> ?p ?o ?g. }

• W2154816471 endingPage "146" @default.
• W2154816471 startingPage "137" @default.
• W2154816471 abstract "A total of 31 healthy volunteers [39 ± 7 (SD) years] and 18 untreated essential hypertensive subjects [43 ± 9 years] collected urine for 24 h after a physical examination and laboratory tests. Radioimmunoassay measurements of angiotensin-(1-7) [Ang-(1-7)] in urine and plasma were done as described previously. Sitting systolic and diastolic blood pressures (± SD) averaged 118 ± 11/74 ± 7 mm Hg and 146 ± 16/96 ± 8 mm Hg in normal and essential hypertensive subjects, respectively (P < .001), whereas 24 h urinary volume was not different in normal and essential hypertensive subjects (P > .05). The concentration of Ang-(1-7) in the urine of normal subjects averaged 62.6 ± 22.6 pmol/L corresponding to a urinary excretion rate of 98.9 ± 44.7 pmol/24 h. Concurrent measurements of plasma Ang-(1-7) showed that the content of Ang-(1-7) in urine was 2.5-fold higher than that measured in the plasma. In contrast, untreated essential hypertensive subjects had lower concentrations and 24 h urinary excretion rates of Ang-(1-7) averaging 39.4 ± 18.0 pmol/L and 60.2 ± 14.6 pmol/24 h, respectively, (P < .001). Differences in the excretory rate of Ang-(1-7) between normal volunteers and essential hypertensive subjects were not modified by normalization of the data by urinary creatinine excretion rates. Urinary concentrations of Ang-(1-7) correlated inversely with systolic, diastolic and mean arterial pressures (r = −0.48, P < .001). Both urinary Ang-(1-7) [odds ratio of 0.92 (95% CI: 0.88–0.97)] and age were independent predictors of systolic blood pressure. These studies demonstrated the presence of Ang-(1-7) in urine and the existence of reduced levels of the heptapeptide in individuals with untreated essential hypertension. The relatively higher concentrations of Ang-(1-7) in urine compared to plasma agrees with data that showed that Ang-(1-7) may contribute to the regulation of blood pressure. The inverse association between Ang-(1-7) and arterial pressure provides a potential marker for the characterization of forms of essential hypertension associated with reduced production or activity of vasodilator hormones." @default.
• W2154816471 created "2016-06-24" @default.
• W2154816471 creator A5003400134 @default.
• W2154816471 creator A5010550865 @default.
• W2154816471 creator A5016588104 @default.
• W2154816471 creator A5028760137 @default.
• W2154816471 creator A5029786236 @default.
• W2154816471 creator A5029955341 @default.
• W2154816471 creator A5042225821 @default.
• W2154816471 creator A5068780401 @default.
• W2154816471 creator A5072715305 @default.
• W2154816471 creator A5079267756 @default.
• W2154816471 creator A5080793363 @default.
• W2154816471 date "1998-02-01" @default.
• W2154816471 modified "2023-10-15" @default.
• W2154816471 title "Characterization of Angiotensin-(1-7) in the Urine of Normal and Essential Hypertensive Subjects" @default.
• W2154816471 cites W1751983523 @default.
• W2154816471 cites W1971715904 @default.
• W2154816471 cites W1973983810 @default.
• W2154816471 cites W1977744864 @default.
• W2154816471 cites W1999107098 @default.
• W2154816471 cites W2005937620 @default.
• W2154816471 cites W2006918766 @default.
• W2154816471 cites W2010861552 @default.
• W2154816471 cites W2012866751 @default.
• W2154816471 cites W2022927987 @default.
• W2154816471 cites W2024416570 @default.
• W2154816471 cites W2041718175 @default.
• W2154816471 cites W2056612734 @default.
• W2154816471 cites W2058478385 @default.
• W2154816471 cites W2062409427 @default.
• W2154816471 cites W2071341579 @default.
• W2154816471 cites W2079577579 @default.
• W2154816471 cites W2080248232 @default.
• W2154816471 cites W2091986375 @default.
• W2154816471 cites W2093449144 @default.
• W2154816471 cites W2108297320 @default.
• W2154816471 cites W2115466950 @default.
• W2154816471 cites W2124534505 @default.
• W2154816471 cites W2135519478 @default.
• W2154816471 cites W2151166210 @default.
• W2154816471 cites W2155216917 @default.
• W2154816471 cites W2283019668 @default.
• W2154816471 cites W2287532303 @default.
• W2154816471 cites W2331763236 @default.
• W2154816471 cites W2410070463 @default.
• W2154816471 cites W2411069971 @default.
• W2154816471 cites W2414410822 @default.
• W2154816471 cites W629613351 @default.
• W2154816471 doi "https://doi.org/10.1016/s0895-7061(97)00400-7" @default.
• W2154816471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9524041" @default.
• W2154816471 hasPublicationYear "1998" @default.
• W2154816471 type Work @default.
• W2154816471 sameAs 2154816471 @default.
• W2154816471 citedByCount "105" @default.
• W2154816471 countsByYear W21548164712012 @default.
• W2154816471 countsByYear W21548164712013 @default.
• W2154816471 countsByYear W21548164712014 @default.
• W2154816471 countsByYear W21548164712015 @default.
• W2154816471 countsByYear W21548164712016 @default.
• W2154816471 countsByYear W21548164712017 @default.
• W2154816471 countsByYear W21548164712018 @default.
• W2154816471 countsByYear W21548164712019 @default.
• W2154816471 countsByYear W21548164712020 @default.
• W2154816471 countsByYear W21548164712021 @default.
• W2154816471 countsByYear W21548164712022 @default.
• W2154816471 countsByYear W21548164712023 @default.
• W2154816471 crossrefType "journal-article" @default.
• W2154816471 hasAuthorship W2154816471A5003400134 @default.
• W2154816471 hasAuthorship W2154816471A5010550865 @default.
• W2154816471 hasAuthorship W2154816471A5016588104 @default.
• W2154816471 hasAuthorship W2154816471A5028760137 @default.
• W2154816471 hasAuthorship W2154816471A5029786236 @default.
• W2154816471 hasAuthorship W2154816471A5029955341 @default.
• W2154816471 hasAuthorship W2154816471A5042225821 @default.
• W2154816471 hasAuthorship W2154816471A5068780401 @default.
• W2154816471 hasAuthorship W2154816471A5072715305 @default.
• W2154816471 hasAuthorship W2154816471A5079267756 @default.
• W2154816471 hasAuthorship W2154816471A5080793363 @default.
• W2154816471 hasBestOaLocation W21548164711 @default.
• W2154816471 hasConcept C10146269 @default.
• W2154816471 hasConcept C126322002 @default.
• W2154816471 hasConcept C134018914 @default.
• W2154816471 hasConcept C138976137 @default.
• W2154816471 hasConcept C176685330 @default.
• W2154816471 hasConcept C198710026 @default.
• W2154816471 hasConcept C2777097880 @default.
• W2154816471 hasConcept C2780026642 @default.
• W2154816471 hasConcept C2780306776 @default.
• W2154816471 hasConcept C2908929049 @default.
• W2154816471 hasConcept C71924100 @default.
• W2154816471 hasConcept C77411442 @default.
• W2154816471 hasConcept C84393581 @default.
• W2154816471 hasConceptScore W2154816471C10146269 @default.
• W2154816471 hasConceptScore W2154816471C126322002 @default.
• W2154816471 hasConceptScore W2154816471C134018914 @default.
• W2154816471 hasConceptScore W2154816471C138976137 @default.
• W2154816471 hasConceptScore W2154816471C176685330 @default.

• next