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- W2154858898 abstract "The response to an inflammatory stimulus is highly variable in critically ill patients and may differ from that of healthy volunteers. One of several distinguishing characteristics between the two groups is an elevated plasma level of cytokines in patients. We hypothesized that an acute elevation in TNF-α, as evoked by a priming dose of purified Escherichia coli endotoxin (LPS), would enhance the inflammatory response to LPS, and we investigated this hypothesis in healthy volunteers in a randomized, double-blind, crossover design." @default.
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- W2154858898 date "2006-01-01" @default.
- W2154858898 modified "2023-10-16" @default.
- W2154858898 doi "https://doi.org/10.1186/cc4434" @default.
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