Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154862441> ?p ?o ?g. }
- W2154862441 endingPage "13" @default.
- W2154862441 startingPage "13" @default.
- W2154862441 abstract "Ocular pathology lessens light's efficacy to maintain optimal circadian entrainment. We examined whether ophthalmic dysfunction explains unique variance in melatonin excretion of older adults over and above the variance explained by daily illumination, medical, and sociodemographic factors. We also examined whether ophthalmic dysfunction influences relationships between ambient illumination and melatonin.Thirty older adults (mean age = 69 years; Blacks = 42% and Whites = 58%) of both genders participated in the study. Demographic and health data were collected at baseline. Participants underwent eye exams at SUNY Downstate Medical Center, wore an actigraph to monitor illumination and sleep, and collected urine specimens to estimate aMT6s concentrations.Hierarchical regression analysis showed that illumination factors explained 29% of the variance in aMT6s mesor. The proportion of variance explained by ophthalmic factors, sleep duration, and race was 10%, 2%, and 2%, respectively. Illumination factors explained 19% of the variance in aMT6s acrophase. The proportion of variance explained by ophthalmic factors, sleep duration, and race was 11%; 17%; and 2%, respectively. Controlling for sleep duration and race reduced the correlations between illumination and melatonin, whereas controlling for ophthalmic factors did not.Ophthalmic exams showed that elevated intraocular pressure and large cup-to-disk ratios were independently associated with earlier melatonin timing. Lower illumination exposure also had independent associations with earlier melatonin timing. Conceivably, ophthalmic and illumination factors might have an additive effect on the timing of melatonin excretion, which in turn might predispose individuals to experience early morning awakenings." @default.
- W2154862441 created "2016-06-24" @default.
- W2154862441 creator A5012766008 @default.
- W2154862441 creator A5025769105 @default.
- W2154862441 creator A5033155304 @default.
- W2154862441 creator A5043206509 @default.
- W2154862441 creator A5048791268 @default.
- W2154862441 creator A5060789638 @default.
- W2154862441 date "2005-12-01" @default.
- W2154862441 modified "2023-09-28" @default.
- W2154862441 title "Daily illumination exposure and melatonin: influence of ophthalmic dysfunction and sleep duration" @default.
- W2154862441 cites W1509486800 @default.
- W2154862441 cites W1603519445 @default.
- W2154862441 cites W181548676 @default.
- W2154862441 cites W1914456932 @default.
- W2154862441 cites W1964842403 @default.
- W2154862441 cites W1978686661 @default.
- W2154862441 cites W1981006932 @default.
- W2154862441 cites W1984116068 @default.
- W2154862441 cites W1990724394 @default.
- W2154862441 cites W1991022676 @default.
- W2154862441 cites W1995176359 @default.
- W2154862441 cites W1995207708 @default.
- W2154862441 cites W1996297699 @default.
- W2154862441 cites W1996462740 @default.
- W2154862441 cites W2001493318 @default.
- W2154862441 cites W2003623977 @default.
- W2154862441 cites W2009077913 @default.
- W2154862441 cites W2009711433 @default.
- W2154862441 cites W2010284336 @default.
- W2154862441 cites W2014028088 @default.
- W2154862441 cites W2019233831 @default.
- W2154862441 cites W2020477056 @default.
- W2154862441 cites W2021182427 @default.
- W2154862441 cites W2025057662 @default.
- W2154862441 cites W2026477142 @default.
- W2154862441 cites W2037525774 @default.
- W2154862441 cites W2038139059 @default.
- W2154862441 cites W2038215683 @default.
- W2154862441 cites W2038854117 @default.
- W2154862441 cites W2041009936 @default.
- W2154862441 cites W2041598866 @default.
- W2154862441 cites W2043842765 @default.
- W2154862441 cites W2049690253 @default.
- W2154862441 cites W2054391435 @default.
- W2154862441 cites W2056699958 @default.
- W2154862441 cites W2064452700 @default.
- W2154862441 cites W2065565096 @default.
- W2154862441 cites W2065911402 @default.
- W2154862441 cites W2073618030 @default.
- W2154862441 cites W2076973235 @default.
- W2154862441 cites W2080853622 @default.
- W2154862441 cites W2082442275 @default.
- W2154862441 cites W2100657003 @default.
- W2154862441 cites W2108914538 @default.
- W2154862441 cites W2121477988 @default.
- W2154862441 cites W2121727279 @default.
- W2154862441 cites W2122162969 @default.
- W2154862441 cites W2139762445 @default.
- W2154862441 cites W2151131721 @default.
- W2154862441 cites W2154022435 @default.
- W2154862441 cites W2165999799 @default.
- W2154862441 cites W2168299405 @default.
- W2154862441 cites W2319811903 @default.
- W2154862441 cites W2418091658 @default.
- W2154862441 cites W2431664620 @default.
- W2154862441 cites W4246222303 @default.
- W2154862441 cites W4287045 @default.
- W2154862441 cites W50776464 @default.
- W2154862441 doi "https://doi.org/10.1186/1740-3391-3-13" @default.
- W2154862441 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1325258" @default.
- W2154862441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16321164" @default.
- W2154862441 hasPublicationYear "2005" @default.
- W2154862441 type Work @default.
- W2154862441 sameAs 2154862441 @default.
- W2154862441 citedByCount "20" @default.
- W2154862441 countsByYear W21548624412013 @default.
- W2154862441 countsByYear W21548624412014 @default.
- W2154862441 countsByYear W21548624412015 @default.
- W2154862441 countsByYear W21548624412016 @default.
- W2154862441 countsByYear W21548624412018 @default.
- W2154862441 countsByYear W21548624412019 @default.
- W2154862441 countsByYear W21548624412021 @default.
- W2154862441 countsByYear W21548624412022 @default.
- W2154862441 countsByYear W21548624412023 @default.
- W2154862441 crossrefType "journal-article" @default.
- W2154862441 hasAuthorship W2154862441A5012766008 @default.
- W2154862441 hasAuthorship W2154862441A5025769105 @default.
- W2154862441 hasAuthorship W2154862441A5033155304 @default.
- W2154862441 hasAuthorship W2154862441A5043206509 @default.
- W2154862441 hasAuthorship W2154862441A5048791268 @default.
- W2154862441 hasAuthorship W2154862441A5060789638 @default.
- W2154862441 hasBestOaLocation W21548624411 @default.
- W2154862441 hasConcept C118487528 @default.
- W2154862441 hasConcept C119857082 @default.
- W2154862441 hasConcept C121446783 @default.
- W2154862441 hasConcept C126322002 @default.
- W2154862441 hasConcept C138528620 @default.