FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154868391> ?p ?o ?g. }

• W2154868391 endingPage "667" @default.
• W2154868391 startingPage "662" @default.
• W2154868391 abstract "Present clinicopathologic staging of non-small cell lung cancer is limited in its ability to provide more than a general prognostic estimate in patients with lung cancer who have resectable disease. This study was performed to identify whether the ability to adapt tumor tissue from resectable (stage I to IIIa) non-small cell lung cancer was associated with a poorer prognosis and an increased risk for early tumor recurrence. We attempted to culture a tumor specimen obtained from 90 patients with resectable non-small cell lung cancer. We used a culture medium conditioned by exposure to the lung cancer cell line A549-1, a known producer of autocrine lung cancer growth factors, and provided tumor colony scaffolding using a feeder layer of inactivated fibroblasts, and found these measures improved tumor culture yields. Twenty-two cell lines were obtained, a success rate of 24.4%. Tumor recurrences were more common (79%) among the culture-positive patients than among the culture-negative patients (37.5%; p < 0.002). For all patients, survival at 19 months in the culture-positive patients was 50.0%, compared with 83.6% in the culture-negative patients (p < 0.005). The median survival for the culture-positive patients was 15 months, versus 21.7 months for the culture-negative patients (p < 0.004). The establishment of a culture was a predictor of shortened survival for patients with stage I disease. In patients with stage I disease, survival at 19 months was 54.5% for the culture-positive patients, versus 89% for the culture-negative patients (p < 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2154868391 created "2016-06-24" @default.
• W2154868391 creator A5014868247 @default.
• W2154868391 creator A5019708734 @default.
• W2154868391 creator A5031746829 @default.
• W2154868391 creator A5044079636 @default.
• W2154868391 creator A5051969889 @default.
• W2154868391 creator A5073144340 @default.
• W2154868391 creator A5077727685 @default.
• W2154868391 creator A5079335804 @default.
• W2154868391 creator A5087572312 @default.
• W2154868391 date "1994-09-01" @default.
• W2154868391 modified "2023-09-25" @default.
• W2154868391 title "Ability to culture resectable non-small cell lung carcinomas is correlated with recurrence" @default.
• W2154868391 cites W109718055 @default.
• W2154868391 cites W1973482241 @default.
• W2154868391 cites W1975549289 @default.
• W2154868391 cites W1976897779 @default.
• W2154868391 cites W1985958706 @default.
• W2154868391 cites W2070896362 @default.
• W2154868391 cites W2085588237 @default.
• W2154868391 cites W2086562589 @default.
• W2154868391 cites W2096831531 @default.
• W2154868391 cites W2113728347 @default.
• W2154868391 cites W2130252581 @default.
• W2154868391 cites W2150363836 @default.
• W2154868391 cites W2164331722 @default.
• W2154868391 cites W2317577047 @default.
• W2154868391 cites W2337358073 @default.
• W2154868391 cites W2339240706 @default.
• W2154868391 cites W2404999653 @default.
• W2154868391 cites W2424871666 @default.
• W2154868391 doi "https://doi.org/10.1016/0003-4975(94)90724-2" @default.
• W2154868391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7944686" @default.
• W2154868391 hasPublicationYear "1994" @default.
• W2154868391 type Work @default.
• W2154868391 sameAs 2154868391 @default.
• W2154868391 citedByCount "4" @default.
• W2154868391 countsByYear W21548683912016 @default.
• W2154868391 crossrefType "journal-article" @default.
• W2154868391 hasAuthorship W2154868391A5014868247 @default.
• W2154868391 hasAuthorship W2154868391A5019708734 @default.
• W2154868391 hasAuthorship W2154868391A5031746829 @default.
• W2154868391 hasAuthorship W2154868391A5044079636 @default.
• W2154868391 hasAuthorship W2154868391A5051969889 @default.
• W2154868391 hasAuthorship W2154868391A5073144340 @default.
• W2154868391 hasAuthorship W2154868391A5077727685 @default.
• W2154868391 hasAuthorship W2154868391A5079335804 @default.
• W2154868391 hasAuthorship W2154868391A5087572312 @default.
• W2154868391 hasConcept C121608353 @default.
• W2154868391 hasConcept C126322002 @default.
• W2154868391 hasConcept C128240485 @default.
• W2154868391 hasConcept C142724271 @default.
• W2154868391 hasConcept C143998085 @default.
• W2154868391 hasConcept C146357865 @default.
• W2154868391 hasConcept C151730666 @default.
• W2154868391 hasConcept C170493617 @default.
• W2154868391 hasConcept C2776178081 @default.
• W2154868391 hasConcept C2776256026 @default.
• W2154868391 hasConcept C2776283816 @default.
• W2154868391 hasConcept C2777714996 @default.
• W2154868391 hasConcept C2779134260 @default.
• W2154868391 hasConcept C54355233 @default.
• W2154868391 hasConcept C71924100 @default.
• W2154868391 hasConcept C81885089 @default.
• W2154868391 hasConcept C86803240 @default.
• W2154868391 hasConcept C90924648 @default.
• W2154868391 hasConceptScore W2154868391C121608353 @default.
• W2154868391 hasConceptScore W2154868391C126322002 @default.
• W2154868391 hasConceptScore W2154868391C128240485 @default.
• W2154868391 hasConceptScore W2154868391C142724271 @default.
• W2154868391 hasConceptScore W2154868391C143998085 @default.
• W2154868391 hasConceptScore W2154868391C146357865 @default.
• W2154868391 hasConceptScore W2154868391C151730666 @default.
• W2154868391 hasConceptScore W2154868391C170493617 @default.
• W2154868391 hasConceptScore W2154868391C2776178081 @default.
• W2154868391 hasConceptScore W2154868391C2776256026 @default.
• W2154868391 hasConceptScore W2154868391C2776283816 @default.
• W2154868391 hasConceptScore W2154868391C2777714996 @default.
• W2154868391 hasConceptScore W2154868391C2779134260 @default.
• W2154868391 hasConceptScore W2154868391C54355233 @default.
• W2154868391 hasConceptScore W2154868391C71924100 @default.
• W2154868391 hasConceptScore W2154868391C81885089 @default.
• W2154868391 hasConceptScore W2154868391C86803240 @default.
• W2154868391 hasConceptScore W2154868391C90924648 @default.
• W2154868391 hasIssue "3" @default.
• W2154868391 hasLocation W21548683911 @default.
• W2154868391 hasLocation W21548683912 @default.
• W2154868391 hasOpenAccess W2154868391 @default.
• W2154868391 hasPrimaryLocation W21548683911 @default.
• W2154868391 hasRelatedWork W1976233355 @default.
• W2154868391 hasRelatedWork W1991288089 @default.
• W2154868391 hasRelatedWork W2022083621 @default.
• W2154868391 hasRelatedWork W2137957356 @default.
• W2154868391 hasRelatedWork W2331442940 @default.
• W2154868391 hasRelatedWork W2364092196 @default.
• W2154868391 hasRelatedWork W2390216242 @default.
• W2154868391 hasRelatedWork W2899552484 @default.

• next