FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154896602> ?p ?o ?g. }

• W2154896602 endingPage "1759" @default.
• W2154896602 startingPage "1750" @default.
• W2154896602 abstract "Interleukins (ILs) are key regulators of immune response. Genetic variation in IL genes may influence breast cancer risk and mortality given their role in cell growth, angiogenesis and regulation of inflammatory process. We examined 16 IL genes with breast cancer risk and mortality in an admixed population of Hispanic/Native American (NA) (2111 cases and 2597 controls) and non-Hispanic white (NHW) (1481 cases and 1585 controls) women. Adaptive Rank Truncated Product (ARTP) analysis was conducted to determine gene significance and lasso (least absolute shrinkage and selection operator) was used to identify potential gene by gene and gene by lifestyle interactions. The pathway was statistically significant for breast cancer risk overall (P ARTP = 0.0006), for women with low NA ancestry (P(ARTP) = 0.01), for premenopausal women (P(ARTP) = 0.02), for estrogen receptor (ER)+/progesterone receptor (PR)+ tumors (P(ARTP) = 0.03) and ER-/PR- tumors (P(ARTP) = 0.02). Eight of the 16 genes evaluated were associated with breast cancer risk (IL1A, IL1B, IL1RN, IL2, IL2RA, IL4, IL6 and IL10); four genes were associated with breast cancer risk among women with low NA ancestry (IL1B, IL6, IL6R and IL10), two were associated with breast cancer risk among women with high NA ancestry (IL2 and IL2RA) and four genes were associated with premenopausal breast cancer risk (IL1A, IL1B, IL2 and IL3). IL4, IL6R, IL8 and IL17A were associated with breast cancer-specific mortality. We confirmed associations with several functional polymorphisms previously associated with breast cancer risk and provide support that their combined effect influences the carcinogenic process." @default.
• W2154896602 created "2016-06-24" @default.
• W2154896602 creator A5007666993 @default.
• W2154896602 creator A5033843313 @default.
• W2154896602 creator A5048602300 @default.
• W2154896602 creator A5050097355 @default.
• W2154896602 creator A5059108165 @default.
• W2154896602 creator A5060833617 @default.
• W2154896602 creator A5061198124 @default.
• W2154896602 creator A5073774490 @default.
• W2154896602 creator A5079655559 @default.
• W2154896602 creator A5085805379 @default.
• W2154896602 date "2014-03-26" @default.
• W2154896602 modified "2023-10-03" @default.
• W2154896602 title "Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities Study" @default.
• W2154896602 cites W1575391368 @default.
• W2154896602 cites W1930449800 @default.
• W2154896602 cites W1967856594 @default.
• W2154896602 cites W1977772566 @default.
• W2154896602 cites W1987558037 @default.
• W2154896602 cites W2002336054 @default.
• W2154896602 cites W2007421579 @default.
• W2154896602 cites W2011924809 @default.
• W2154896602 cites W2016170751 @default.
• W2154896602 cites W2020025403 @default.
• W2154896602 cites W2028194167 @default.
• W2154896602 cites W2030678748 @default.
• W2154896602 cites W2030705868 @default.
• W2154896602 cites W2031576122 @default.
• W2154896602 cites W2035853760 @default.
• W2154896602 cites W2042966150 @default.
• W2154896602 cites W2049862576 @default.
• W2154896602 cites W2056072848 @default.
• W2154896602 cites W2056117410 @default.
• W2154896602 cites W2058217567 @default.
• W2154896602 cites W205830912 @default.
• W2154896602 cites W2065051848 @default.
• W2154896602 cites W2067263364 @default.
• W2154896602 cites W2070585499 @default.
• W2154896602 cites W2073686472 @default.
• W2154896602 cites W2077247677 @default.
• W2154896602 cites W2080994268 @default.
• W2154896602 cites W2085866528 @default.
• W2154896602 cites W2085885623 @default.
• W2154896602 cites W2087467445 @default.
• W2154896602 cites W2090450480 @default.
• W2154896602 cites W2091849639 @default.
• W2154896602 cites W2095020046 @default.
• W2154896602 cites W2096715492 @default.
• W2154896602 cites W2098126593 @default.
• W2154896602 cites W2105850755 @default.
• W2154896602 cites W2107755054 @default.
• W2154896602 cites W2110567472 @default.
• W2154896602 cites W2115651060 @default.
• W2154896602 cites W2116279598 @default.
• W2154896602 cites W2118785471 @default.
• W2154896602 cites W2122882840 @default.
• W2154896602 cites W2138749386 @default.
• W2154896602 cites W2145840941 @default.
• W2154896602 cites W2155682417 @default.
• W2154896602 cites W2158489424 @default.
• W2154896602 cites W2160679814 @default.
• W2154896602 cites W2171960463 @default.
• W2154896602 doi "https://doi.org/10.1093/carcin/bgu078" @default.
• W2154896602 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4123645" @default.
• W2154896602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24670917" @default.
• W2154896602 hasPublicationYear "2014" @default.
• W2154896602 type Work @default.
• W2154896602 sameAs 2154896602 @default.
• W2154896602 citedByCount "34" @default.
• W2154896602 countsByYear W21548966022015 @default.
• W2154896602 countsByYear W21548966022016 @default.
• W2154896602 countsByYear W21548966022017 @default.
• W2154896602 countsByYear W21548966022018 @default.
• W2154896602 countsByYear W21548966022019 @default.
• W2154896602 countsByYear W21548966022020 @default.
• W2154896602 countsByYear W21548966022021 @default.
• W2154896602 countsByYear W21548966022022 @default.
• W2154896602 countsByYear W21548966022023 @default.
• W2154896602 crossrefType "journal-article" @default.
• W2154896602 hasAuthorship W2154896602A5007666993 @default.
• W2154896602 hasAuthorship W2154896602A5033843313 @default.
• W2154896602 hasAuthorship W2154896602A5048602300 @default.
• W2154896602 hasAuthorship W2154896602A5050097355 @default.
• W2154896602 hasAuthorship W2154896602A5059108165 @default.
• W2154896602 hasAuthorship W2154896602A5060833617 @default.
• W2154896602 hasAuthorship W2154896602A5061198124 @default.
• W2154896602 hasAuthorship W2154896602A5073774490 @default.
• W2154896602 hasAuthorship W2154896602A5079655559 @default.
• W2154896602 hasAuthorship W2154896602A5085805379 @default.
• W2154896602 hasBestOaLocation W21548966022 @default.
• W2154896602 hasConcept C121608353 @default.
• W2154896602 hasConcept C126322002 @default.
• W2154896602 hasConcept C143998085 @default.
• W2154896602 hasConcept C203014093 @default.
• W2154896602 hasConcept C2908647359 @default.
• W2154896602 hasConcept C530470458 @default.
• W2154896602 hasConcept C71924100 @default.

• next