FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154901678> ?p ?o ?g. }

• W2154901678 endingPage "1453" @default.
• W2154901678 startingPage "1445" @default.
• W2154901678 abstract "Epilepsy surgery can be successful in children with extensive congenital or early acquired focal or hemispheric brain lesion on magnetic resonance imaging (MRI) despite generalized interictal epileptiform discharges (IEDs). The aim of this study was to assess if rapid eye movement (REM) sleep reduced generalized IEDs and revealed lateralized IEDs to identify the epileptogenic hemisphere in children with generalized IEDs and normal/subtle changes on MRI.We studied 20 children with generalized IEDs on scalp electroencephalography (EEG) and normal/subtle changes on MRI who underwent intracranial video-EEG for epilepsy surgery. We assessed a minimum of 100 IEDs during REM, non-REM, and wakefulness, and assigned the distribution (generalized, left, or right hemisphere) to each IED. The number of lobes in the resected areas and seizure outcome were compared between 20 children with generalized IEDs and a comparison group of 28 children without generalized IEDs.The mean occurrence rate of generalized IEDs during REM (37%) was significantly lower than that during non-REM (67%, p < 0.001) and wakefulness (54%, p = 0.003). The number of children whose largest number of IEDs was lateralized in REM was significantly higher than that in non-REM (15 vs. 3 children, 75% vs. 15%, p < 0.001). The hemisphere with lateralized IEDs among three states corresponded with the surgical side in 16 children with generalized IEDs. Seventeen children (85%) with generalized IEDs and 27 (96%) without generalized IEDs underwent resective surgery. Multilobar resection was required for 16 children (94%) with generalized IEDs more frequently than 7 children (26%) without generalized IEDs (p < 0.001). Thirteen children (77%) with generalized IEDs and 19 (73%) without generalized IEDs were seizure-free with a mean of 3.3 years of follow-up.Our study demonstrates the importance of assessing REM in children with generalized IEDs as it reveals lateralized epileptogenic spikes. Seizure freedom may be achieved with multilobar resection in these children with generalized IEDs and normal/subtle changes on MRI. Generalized IEDs in children with normal/subtle changes on MRI should not preclude surgical resection." @default.
• W2154901678 created "2016-06-24" @default.
• W2154901678 creator A5002892990 @default.
• W2154901678 creator A5011219252 @default.
• W2154901678 creator A5019849501 @default.
• W2154901678 creator A5026618924 @default.
• W2154901678 creator A5036065086 @default.
• W2154901678 creator A5036262197 @default.
• W2154901678 creator A5045772630 @default.
• W2154901678 creator A5046517361 @default.
• W2154901678 creator A5050967174 @default.
• W2154901678 creator A5059063557 @default.
• W2154901678 creator A5060346938 @default.
• W2154901678 creator A5067215084 @default.
• W2154901678 creator A5069806483 @default.
• W2154901678 creator A5069982074 @default.
• W2154901678 creator A5071108360 @default.
• W2154901678 creator A5071267147 @default.
• W2154901678 creator A5083177175 @default.
• W2154901678 creator A5089388893 @default.
• W2154901678 date "2015-07-15" @default.
• W2154901678 modified "2023-10-05" @default.
• W2154901678 title "Rapid eye movement sleep reveals epileptogenic spikes for resective surgery in children with generalized interictal discharges" @default.
• W2154901678 cites W1518040786 @default.
• W2154901678 cites W1533320261 @default.
• W2154901678 cites W1582703563 @default.
• W2154901678 cites W1854850957 @default.
• W2154901678 cites W189888755 @default.
• W2154901678 cites W1964011929 @default.
• W2154901678 cites W1965930146 @default.
• W2154901678 cites W1975242759 @default.
• W2154901678 cites W1977752791 @default.
• W2154901678 cites W1978833170 @default.
• W2154901678 cites W1981183753 @default.
• W2154901678 cites W1983518400 @default.
• W2154901678 cites W1985522940 @default.
• W2154901678 cites W2016276034 @default.
• W2154901678 cites W2018417677 @default.
• W2154901678 cites W2026019430 @default.
• W2154901678 cites W2029189091 @default.
• W2154901678 cites W2035998176 @default.
• W2154901678 cites W2043210191 @default.
• W2154901678 cites W2060649512 @default.
• W2154901678 cites W2075945373 @default.
• W2154901678 cites W2088622784 @default.
• W2154901678 cites W2099478180 @default.
• W2154901678 cites W2105727230 @default.
• W2154901678 cites W2119021808 @default.
• W2154901678 cites W2139147515 @default.
• W2154901678 cites W4245932665 @default.
• W2154901678 cites W7692620 @default.
• W2154901678 doi "https://doi.org/10.1111/epi.13081" @default.
• W2154901678 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26174651" @default.
• W2154901678 hasPublicationYear "2015" @default.
• W2154901678 type Work @default.
• W2154901678 sameAs 2154901678 @default.
• W2154901678 citedByCount "25" @default.
• W2154901678 countsByYear W21549016782016 @default.
• W2154901678 countsByYear W21549016782017 @default.
• W2154901678 countsByYear W21549016782018 @default.
• W2154901678 countsByYear W21549016782019 @default.
• W2154901678 countsByYear W21549016782020 @default.
• W2154901678 countsByYear W21549016782021 @default.
• W2154901678 countsByYear W21549016782022 @default.
• W2154901678 countsByYear W21549016782023 @default.
• W2154901678 crossrefType "journal-article" @default.
• W2154901678 hasAuthorship W2154901678A5002892990 @default.
• W2154901678 hasAuthorship W2154901678A5011219252 @default.
• W2154901678 hasAuthorship W2154901678A5019849501 @default.
• W2154901678 hasAuthorship W2154901678A5026618924 @default.
• W2154901678 hasAuthorship W2154901678A5036065086 @default.
• W2154901678 hasAuthorship W2154901678A5036262197 @default.
• W2154901678 hasAuthorship W2154901678A5045772630 @default.
• W2154901678 hasAuthorship W2154901678A5046517361 @default.
• W2154901678 hasAuthorship W2154901678A5050967174 @default.
• W2154901678 hasAuthorship W2154901678A5059063557 @default.
• W2154901678 hasAuthorship W2154901678A5060346938 @default.
• W2154901678 hasAuthorship W2154901678A5067215084 @default.
• W2154901678 hasAuthorship W2154901678A5069806483 @default.
• W2154901678 hasAuthorship W2154901678A5069982074 @default.
• W2154901678 hasAuthorship W2154901678A5071108360 @default.
• W2154901678 hasAuthorship W2154901678A5071267147 @default.
• W2154901678 hasAuthorship W2154901678A5083177175 @default.
• W2154901678 hasAuthorship W2154901678A5089388893 @default.
• W2154901678 hasBestOaLocation W21549016781 @default.
• W2154901678 hasConcept C126838900 @default.
• W2154901678 hasConcept C141071460 @default.
• W2154901678 hasConcept C143409427 @default.
• W2154901678 hasConcept C153050134 @default.
• W2154901678 hasConcept C15744967 @default.
• W2154901678 hasConcept C169760540 @default.
• W2154901678 hasConcept C17755696 @default.
• W2154901678 hasConcept C2778186239 @default.
• W2154901678 hasConcept C2778515351 @default.
• W2154901678 hasConcept C2779320081 @default.
• W2154901678 hasConcept C2779979230 @default.
• W2154901678 hasConcept C2780803581 @default.
• W2154901678 hasConcept C522805319 @default.

• next