Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154909080> ?p ?o ?g. }
- W2154909080 endingPage "114" @default.
- W2154909080 startingPage "107" @default.
- W2154909080 abstract "A number of 2-phenoxyalkylaminoalkyl- and 2-[1,4]benzodioxanylmethylaminoalkyl-3(2H)-pyridazinones were synthesized and tested for hypotensive and antihypertensive activity as well as for α1- and α2-adrenoceptor binding affinities. Some derivatives, eg 5.5, 5.9, 5.12, 6.4 and 6.10, showed strong hypotensive/antihypertensive effect and high affinity for α2- and α1-adrenoceptors. Compound 5.5 was selected for clinical study. In its mode of action a potassium channel opening activity may also be involved." @default.
- W2154909080 created "2016-06-24" @default.
- W2154909080 creator A5003937794 @default.
- W2154909080 creator A5013201246 @default.
- W2154909080 creator A5021093905 @default.
- W2154909080 creator A5033010272 @default.
- W2154909080 creator A5044776112 @default.
- W2154909080 creator A5063159761 @default.
- W2154909080 creator A5063605014 @default.
- W2154909080 creator A5065052900 @default.
- W2154909080 creator A5066911504 @default.
- W2154909080 creator A5084064063 @default.
- W2154909080 creator A5086778207 @default.
- W2154909080 creator A5000775152 @default.
- W2154909080 date "1992-03-01" @default.
- W2154909080 modified "2023-09-26" @default.
- W2154909080 title "Synthesis, antihypertensive and α-adrenoceptor activity of novel 2-aminoalkyl-3(2H)-pyridazinones" @default.
- W2154909080 cites W1967325029 @default.
- W2154909080 cites W1986740071 @default.
- W2154909080 cites W1988242982 @default.
- W2154909080 cites W2000220086 @default.
- W2154909080 cites W2004452188 @default.
- W2154909080 cites W2012254875 @default.
- W2154909080 cites W2022335174 @default.
- W2154909080 cites W2032070384 @default.
- W2154909080 cites W2032614972 @default.
- W2154909080 cites W2033756350 @default.
- W2154909080 cites W2045288200 @default.
- W2154909080 cites W2058939764 @default.
- W2154909080 cites W2073791831 @default.
- W2154909080 cites W2074631079 @default.
- W2154909080 cites W2077035757 @default.
- W2154909080 cites W2094125056 @default.
- W2154909080 cites W2318516848 @default.
- W2154909080 cites W2320417867 @default.
- W2154909080 cites W2321165065 @default.
- W2154909080 cites W2326607247 @default.
- W2154909080 cites W2950932153 @default.
- W2154909080 cites W4255538226 @default.
- W2154909080 cites W2027248979 @default.
- W2154909080 doi "https://doi.org/10.1016/0223-5234(92)90098-l" @default.
- W2154909080 hasPublicationYear "1992" @default.
- W2154909080 type Work @default.
- W2154909080 sameAs 2154909080 @default.
- W2154909080 citedByCount "14" @default.
- W2154909080 countsByYear W21549090802012 @default.
- W2154909080 countsByYear W21549090802013 @default.
- W2154909080 countsByYear W21549090802017 @default.
- W2154909080 countsByYear W21549090802021 @default.
- W2154909080 countsByYear W21549090802023 @default.
- W2154909080 crossrefType "journal-article" @default.
- W2154909080 hasAuthorship W2154909080A5000775152 @default.
- W2154909080 hasAuthorship W2154909080A5003937794 @default.
- W2154909080 hasAuthorship W2154909080A5013201246 @default.
- W2154909080 hasAuthorship W2154909080A5021093905 @default.
- W2154909080 hasAuthorship W2154909080A5033010272 @default.
- W2154909080 hasAuthorship W2154909080A5044776112 @default.
- W2154909080 hasAuthorship W2154909080A5063159761 @default.
- W2154909080 hasAuthorship W2154909080A5063605014 @default.
- W2154909080 hasAuthorship W2154909080A5065052900 @default.
- W2154909080 hasAuthorship W2154909080A5066911504 @default.
- W2154909080 hasAuthorship W2154909080A5084064063 @default.
- W2154909080 hasAuthorship W2154909080A5086778207 @default.
- W2154909080 hasConcept C116073593 @default.
- W2154909080 hasConcept C121587506 @default.
- W2154909080 hasConcept C170493617 @default.
- W2154909080 hasConcept C178790620 @default.
- W2154909080 hasConcept C185592680 @default.
- W2154909080 hasConcept C193042331 @default.
- W2154909080 hasConcept C202751555 @default.
- W2154909080 hasConcept C2776120743 @default.
- W2154909080 hasConcept C2780283098 @default.
- W2154909080 hasConcept C40465926 @default.
- W2154909080 hasConcept C517785266 @default.
- W2154909080 hasConcept C55493867 @default.
- W2154909080 hasConcept C71240020 @default.
- W2154909080 hasConcept C71924100 @default.
- W2154909080 hasConcept C98274493 @default.
- W2154909080 hasConceptScore W2154909080C116073593 @default.
- W2154909080 hasConceptScore W2154909080C121587506 @default.
- W2154909080 hasConceptScore W2154909080C170493617 @default.
- W2154909080 hasConceptScore W2154909080C178790620 @default.
- W2154909080 hasConceptScore W2154909080C185592680 @default.
- W2154909080 hasConceptScore W2154909080C193042331 @default.
- W2154909080 hasConceptScore W2154909080C202751555 @default.
- W2154909080 hasConceptScore W2154909080C2776120743 @default.
- W2154909080 hasConceptScore W2154909080C2780283098 @default.
- W2154909080 hasConceptScore W2154909080C40465926 @default.
- W2154909080 hasConceptScore W2154909080C517785266 @default.
- W2154909080 hasConceptScore W2154909080C55493867 @default.
- W2154909080 hasConceptScore W2154909080C71240020 @default.
- W2154909080 hasConceptScore W2154909080C71924100 @default.
- W2154909080 hasConceptScore W2154909080C98274493 @default.
- W2154909080 hasIssue "2" @default.
- W2154909080 hasLocation W21549090801 @default.
- W2154909080 hasOpenAccess W2154909080 @default.
- W2154909080 hasPrimaryLocation W21549090801 @default.
- W2154909080 hasRelatedWork W1979430889 @default.