Matches in SemOpenAlex for { <https://semopenalex.org/work/W2154996842> ?p ?o ?g. }
- W2154996842 endingPage "7902" @default.
- W2154996842 startingPage "7891" @default.
- W2154996842 abstract "Tst-1/SCIP/Oct-6, a POU domain transcription factor, is transiently expressed by developing Schwann cells and is required for their normal development into a myelinating phenotype. In tst-1/scip/oct-6 –null sciatic nerves, Schwann cells are transiently arrested at the “promyelinating” stage, when they have a one-to-one relationship with an axon but before they have elaborated a myelin sheath. To determine when Schwann cells express Tst-1/SCIP/Oct-6, we examined β-galactosidase (β-gal) expression in heterozygous tst-1/scip/oct-6 mice, in which one copy of the tst-1/scip/oct-6 gene has been replaced with the LacZ gene. β-Gal expression from the LacZ gene seems to parallel Tst-1/SCIP/Oct-6 expression from the endogenous tst-1/scip/oct-6 gene in developing and regenerating sciatic nerves. Furthermore, electron microscopic examination of 5bromo-4-chloro-3-indolyl-β- d -galactopyranoside– (X-gal) and halogenated indolyl-β- d -galactoside– (Bluo-gal) stained nerves showed that promyelinating Schwann cells express the highest levels of β-gal, both in developing and in regenerating nerves. Thus, the expression of β-gal, a surrogate marker of Tst-1/SCIP/Oct-6, peaks at the same stage of Schwann cell development at which development is arrested in tst-1/scip/oct-6 –null mice, indicating that Tst-1/SCIP/Oct-6 has a critical role in promyelinating Schwann cells." @default.
- W2154996842 created "2016-06-24" @default.
- W2154996842 creator A5000068004 @default.
- W2154996842 creator A5010248548 @default.
- W2154996842 creator A5035007666 @default.
- W2154996842 creator A5069642384 @default.
- W2154996842 date "1998-10-01" @default.
- W2154996842 modified "2023-10-18" @default.
- W2154996842 title "Promyelinating Schwann Cells Express Tst-1/SCIP/Oct-6" @default.
- W2154996842 cites W106570787 @default.
- W2154996842 cites W1865922014 @default.
- W2154996842 cites W1970383028 @default.
- W2154996842 cites W1976138487 @default.
- W2154996842 cites W1976381690 @default.
- W2154996842 cites W2005821807 @default.
- W2154996842 cites W2006296015 @default.
- W2154996842 cites W2006591452 @default.
- W2154996842 cites W2014399514 @default.
- W2154996842 cites W2019964690 @default.
- W2154996842 cites W2023262022 @default.
- W2154996842 cites W2028934778 @default.
- W2154996842 cites W2030046231 @default.
- W2154996842 cites W2034386955 @default.
- W2154996842 cites W2036465448 @default.
- W2154996842 cites W2041212031 @default.
- W2154996842 cites W2041355051 @default.
- W2154996842 cites W2042960433 @default.
- W2154996842 cites W2045691215 @default.
- W2154996842 cites W2049215950 @default.
- W2154996842 cites W2051738169 @default.
- W2154996842 cites W2057974362 @default.
- W2154996842 cites W2060107042 @default.
- W2154996842 cites W2060960668 @default.
- W2154996842 cites W2063251624 @default.
- W2154996842 cites W2063499134 @default.
- W2154996842 cites W2065505689 @default.
- W2154996842 cites W2066070300 @default.
- W2154996842 cites W2074502125 @default.
- W2154996842 cites W2082112737 @default.
- W2154996842 cites W2101229058 @default.
- W2154996842 cites W2103179205 @default.
- W2154996842 cites W2129329466 @default.
- W2154996842 cites W2145599313 @default.
- W2154996842 cites W2152664328 @default.
- W2154996842 cites W2316624175 @default.
- W2154996842 doi "https://doi.org/10.1523/jneurosci.18-19-07891.1998" @default.
- W2154996842 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6792991" @default.
- W2154996842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9742157" @default.
- W2154996842 hasPublicationYear "1998" @default.
- W2154996842 type Work @default.
- W2154996842 sameAs 2154996842 @default.
- W2154996842 citedByCount "84" @default.
- W2154996842 countsByYear W21549968422012 @default.
- W2154996842 countsByYear W21549968422013 @default.
- W2154996842 countsByYear W21549968422014 @default.
- W2154996842 countsByYear W21549968422015 @default.
- W2154996842 countsByYear W21549968422016 @default.
- W2154996842 countsByYear W21549968422017 @default.
- W2154996842 countsByYear W21549968422018 @default.
- W2154996842 countsByYear W21549968422019 @default.
- W2154996842 countsByYear W21549968422020 @default.
- W2154996842 countsByYear W21549968422021 @default.
- W2154996842 countsByYear W21549968422022 @default.
- W2154996842 crossrefType "journal-article" @default.
- W2154996842 hasAuthorship W2154996842A5000068004 @default.
- W2154996842 hasAuthorship W2154996842A5010248548 @default.
- W2154996842 hasAuthorship W2154996842A5035007666 @default.
- W2154996842 hasAuthorship W2154996842A5069642384 @default.
- W2154996842 hasBestOaLocation W21549968421 @default.
- W2154996842 hasConcept C104317684 @default.
- W2154996842 hasConcept C150194340 @default.
- W2154996842 hasConcept C153911025 @default.
- W2154996842 hasConcept C169760540 @default.
- W2154996842 hasConcept C2777004073 @default.
- W2154996842 hasConcept C2778609137 @default.
- W2154996842 hasConcept C529278444 @default.
- W2154996842 hasConcept C54355233 @default.
- W2154996842 hasConcept C86803240 @default.
- W2154996842 hasConcept C95444343 @default.
- W2154996842 hasConceptScore W2154996842C104317684 @default.
- W2154996842 hasConceptScore W2154996842C150194340 @default.
- W2154996842 hasConceptScore W2154996842C153911025 @default.
- W2154996842 hasConceptScore W2154996842C169760540 @default.
- W2154996842 hasConceptScore W2154996842C2777004073 @default.
- W2154996842 hasConceptScore W2154996842C2778609137 @default.
- W2154996842 hasConceptScore W2154996842C529278444 @default.
- W2154996842 hasConceptScore W2154996842C54355233 @default.
- W2154996842 hasConceptScore W2154996842C86803240 @default.
- W2154996842 hasConceptScore W2154996842C95444343 @default.
- W2154996842 hasIssue "19" @default.
- W2154996842 hasLocation W21549968421 @default.
- W2154996842 hasLocation W21549968422 @default.
- W2154996842 hasLocation W21549968423 @default.
- W2154996842 hasLocation W21549968424 @default.
- W2154996842 hasOpenAccess W2154996842 @default.
- W2154996842 hasPrimaryLocation W21549968421 @default.
- W2154996842 hasRelatedWork W1655540037 @default.
- W2154996842 hasRelatedWork W1978266038 @default.