FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155013671> ?p ?o ?g. }

• W2155013671 endingPage "2054" @default.
• W2155013671 startingPage "2049" @default.
• W2155013671 abstract "Background and Purpose — In cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), water diffusion changes suggestive of microstructural tissue alterations have been recently reported in abnormal- and normal-appearing white matter as seen on T2-weighted images. In the subcortical gray matter, typical lacunar infarcts are repeatedly observed. Whether microstructural tissue changes are also present outside these lesions within the putamen or thalamus remains unknown. Methods — We used diffusion tensor imaging, an MRI method highly sensitive to cerebral microstructure, in 20 CADASIL patients and 12 controls. Both the trace of the diffusion tensor [Tr(D)] and an anisotropic diffusion index (volume ratio) of diffusion were measured within the putamen and thalamus outside typical lacunar infarcts as detected on both T1- and T2-weighted images. Results — A significant increase in Tr(D) and a decrease in anisotropy were observed in the putamen and thalamus in patients. The right/left indices of Tr(D) in the thalamus, but not in the putamen, were strongly correlated with the corresponding indices calculated in the white matter of the centrum semiovale. In addition, the diffusion increase in the thalamus was positively correlated with Tr(D) and with the load of small deep infarcts within the white matter and negatively correlated with the Mini-Mental State Examination score. Conclusions — Our results suggest that microstructural tissue alterations are present in the putamen and thalamus, outside the typical lacunar infarcts in CADASIL. In the thalamus, these microstructural changes appear constant and are even observed in asymptomatic subjects. Some of these thalamic changes appear to result from degeneration of thalamocortical pathways secondary to ischemic white matter damage. The importance of this degenerative phenomenon in the pathophysiology of CADASIL requires further investigation." @default.
• W2155013671 created "2016-06-24" @default.
• W2155013671 creator A5002570397 @default.
• W2155013671 creator A5019140225 @default.
• W2155013671 creator A5031239281 @default.
• W2155013671 creator A5032362696 @default.
• W2155013671 creator A5036133434 @default.
• W2155013671 creator A5049489554 @default.
• W2155013671 creator A5066121091 @default.
• W2155013671 creator A5087289959 @default.
• W2155013671 creator A5087903264 @default.
• W2155013671 date "2001-09-01" @default.
• W2155013671 modified "2023-10-16" @default.
• W2155013671 title "Diffusion Tensor Imaging Study of Subcortical Gray Matter in CADASIL" @default.
• W2155013671 cites W1966613757 @default.
• W2155013671 cites W1969586818 @default.
• W2155013671 cites W1981204020 @default.
• W2155013671 cites W1990634803 @default.
• W2155013671 cites W2000547934 @default.
• W2155013671 cites W2010123464 @default.
• W2155013671 cites W2020067709 @default.
• W2155013671 cites W2021556801 @default.
• W2155013671 cites W2022530159 @default.
• W2155013671 cites W2028633601 @default.
• W2155013671 cites W2033628588 @default.
• W2155013671 cites W2038707210 @default.
• W2155013671 cites W2041401995 @default.
• W2155013671 cites W2042712168 @default.
• W2155013671 cites W2054220071 @default.
• W2155013671 cites W2059167077 @default.
• W2155013671 cites W2110431535 @default.
• W2155013671 cites W2129841144 @default.
• W2155013671 cites W2139382992 @default.
• W2155013671 cites W2147593622 @default.
• W2155013671 cites W2153287135 @default.
• W2155013671 cites W2157035009 @default.
• W2155013671 cites W2157951377 @default.
• W2155013671 cites W2323910566 @default.
• W2155013671 cites W28946685 @default.
• W2155013671 doi "https://doi.org/10.1161/hs0901.094255" @default.
• W2155013671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11546896" @default.
• W2155013671 hasPublicationYear "2001" @default.
• W2155013671 type Work @default.
• W2155013671 sameAs 2155013671 @default.
• W2155013671 citedByCount "63" @default.
• W2155013671 countsByYear W21550136712012 @default.
• W2155013671 countsByYear W21550136712013 @default.
• W2155013671 countsByYear W21550136712014 @default.
• W2155013671 countsByYear W21550136712015 @default.
• W2155013671 countsByYear W21550136712016 @default.
• W2155013671 countsByYear W21550136712017 @default.
• W2155013671 countsByYear W21550136712019 @default.
• W2155013671 countsByYear W21550136712020 @default.
• W2155013671 countsByYear W21550136712021 @default.
• W2155013671 countsByYear W21550136712022 @default.
• W2155013671 countsByYear W21550136712023 @default.
• W2155013671 crossrefType "journal-article" @default.
• W2155013671 hasAuthorship W2155013671A5002570397 @default.
• W2155013671 hasAuthorship W2155013671A5019140225 @default.
• W2155013671 hasAuthorship W2155013671A5031239281 @default.
• W2155013671 hasAuthorship W2155013671A5032362696 @default.
• W2155013671 hasAuthorship W2155013671A5036133434 @default.
• W2155013671 hasAuthorship W2155013671A5049489554 @default.
• W2155013671 hasAuthorship W2155013671A5066121091 @default.
• W2155013671 hasAuthorship W2155013671A5087289959 @default.
• W2155013671 hasAuthorship W2155013671A5087903264 @default.
• W2155013671 hasBestOaLocation W21550136711 @default.
• W2155013671 hasConcept C105702510 @default.
• W2155013671 hasConcept C126322002 @default.
• W2155013671 hasConcept C126838900 @default.
• W2155013671 hasConcept C142724271 @default.
• W2155013671 hasConcept C143409427 @default.
• W2155013671 hasConcept C149550507 @default.
• W2155013671 hasConcept C2778583010 @default.
• W2155013671 hasConcept C2779246727 @default.
• W2155013671 hasConcept C2779268494 @default.
• W2155013671 hasConcept C2779714222 @default.
• W2155013671 hasConcept C2781192897 @default.
• W2155013671 hasConcept C71924100 @default.
• W2155013671 hasConcept C89916169 @default.
• W2155013671 hasConceptScore W2155013671C105702510 @default.
• W2155013671 hasConceptScore W2155013671C126322002 @default.
• W2155013671 hasConceptScore W2155013671C126838900 @default.
• W2155013671 hasConceptScore W2155013671C142724271 @default.
• W2155013671 hasConceptScore W2155013671C143409427 @default.
• W2155013671 hasConceptScore W2155013671C149550507 @default.
• W2155013671 hasConceptScore W2155013671C2778583010 @default.
• W2155013671 hasConceptScore W2155013671C2779246727 @default.
• W2155013671 hasConceptScore W2155013671C2779268494 @default.
• W2155013671 hasConceptScore W2155013671C2779714222 @default.
• W2155013671 hasConceptScore W2155013671C2781192897 @default.
• W2155013671 hasConceptScore W2155013671C71924100 @default.
• W2155013671 hasConceptScore W2155013671C89916169 @default.
• W2155013671 hasIssue "9" @default.
• W2155013671 hasLocation W21550136711 @default.
• W2155013671 hasLocation W21550136712 @default.
• W2155013671 hasLocation W21550136713 @default.
• W2155013671 hasLocation W21550136714 @default.

• next