FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155014461> ?p ?o ?g. }

• W2155014461 endingPage "364" @default.
• W2155014461 startingPage "356" @default.
• W2155014461 abstract "Infections due to Histoplasma capsulatum occur as a result of the inhalation of airborne microconidia of the mold into the alveoli of the lungs. In this study we quantified the transformation over time of conidia into yeast-like cells within macrophages (MΦ) and dendritic cells (DC). Conidia from strain G217B which had been surface labeled with carboxy-fluorescein succinimidyl ester (CFSE), or conidia from strain G217B that expresses green fluorescent protein (GFP) only in the yeast phase, were used to infect MΦ and DC. At various time points, numbers of intracellular conidia or yeasts were quantified via phase-contrast and fluorescent microscopy. Transformation of conidia from non-GFP-expressing G217B also was quantified by their incorporation of ³H-leucine. In both human and murine MΦ, numerous yeast-like cells appeared by day 3 post-infection. The time course of conidia transformation into yeasts in culture medium was the same as in MΦ. However, transformation of conidia to yeasts was significantly restricted in human DC and murine lung DC. In DC, significant numbers of yeasts did not appear until 5 days post-infection. Further, MΦ monolayers were destroyed by day 6-7 post-infection, whereas DC monolayers remained intact throughout the study period. These data suggest that in vivo, conidia may transform into yeast-like cells efficiently whether or not they are phagocytosed by MΦ, but not when ingested by DC." @default.
• W2155014461 created "2016-06-24" @default.
• W2155014461 creator A5009189137 @default.
• W2155014461 creator A5047629667 @default.
• W2155014461 creator A5058310459 @default.
• W2155014461 date "2011-05-01" @default.
• W2155014461 modified "2023-09-23" @default.
• W2155014461 title "Dendritic cells restrict the transformation of<i>Histoplasma capsulatum</i>conidia into yeasts" @default.
• W2155014461 cites W1670380555 @default.
• W2155014461 cites W1712432239 @default.
• W2155014461 cites W1758275058 @default.
• W2155014461 cites W1827682233 @default.
• W2155014461 cites W1843542804 @default.
• W2155014461 cites W1879557309 @default.
• W2155014461 cites W1956479436 @default.
• W2155014461 cites W1968770412 @default.
• W2155014461 cites W2000022447 @default.
• W2155014461 cites W2021374438 @default.
• W2155014461 cites W2031244360 @default.
• W2155014461 cites W2047718023 @default.
• W2155014461 cites W2053141890 @default.
• W2155014461 cites W2062041228 @default.
• W2155014461 cites W2065108829 @default.
• W2155014461 cites W2089020785 @default.
• W2155014461 cites W2090750569 @default.
• W2155014461 cites W2098811788 @default.
• W2155014461 cites W2102520038 @default.
• W2155014461 cites W2111461426 @default.
• W2155014461 cites W2123655574 @default.
• W2155014461 cites W2127685293 @default.
• W2155014461 cites W2150595991 @default.
• W2155014461 cites W2154154548 @default.
• W2155014461 cites W2154278534 @default.
• W2155014461 cites W2154873940 @default.
• W2155014461 cites W2165327894 @default.
• W2155014461 cites W2304510420 @default.
• W2155014461 cites W2314382466 @default.
• W2155014461 cites W2319182357 @default.
• W2155014461 cites W2518921137 @default.
• W2155014461 cites W4233148197 @default.
• W2155014461 cites W4240445572 @default.
• W2155014461 cites W4246295825 @default.
• W2155014461 cites W4297700719 @default.
• W2155014461 doi "https://doi.org/10.3109/13693786.2010.531295" @default.
• W2155014461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21039309" @default.
• W2155014461 hasPublicationYear "2011" @default.
• W2155014461 type Work @default.
• W2155014461 sameAs 2155014461 @default.
• W2155014461 citedByCount "19" @default.
• W2155014461 countsByYear W21550144612013 @default.
• W2155014461 countsByYear W21550144612014 @default.
• W2155014461 countsByYear W21550144612015 @default.
• W2155014461 countsByYear W21550144612016 @default.
• W2155014461 countsByYear W21550144612017 @default.
• W2155014461 countsByYear W21550144612018 @default.
• W2155014461 countsByYear W21550144612019 @default.
• W2155014461 countsByYear W21550144612022 @default.
• W2155014461 countsByYear W21550144612023 @default.
• W2155014461 crossrefType "journal-article" @default.
• W2155014461 hasAuthorship W2155014461A5009189137 @default.
• W2155014461 hasAuthorship W2155014461A5047629667 @default.
• W2155014461 hasAuthorship W2155014461A5058310459 @default.
• W2155014461 hasBestOaLocation W21550144611 @default.
• W2155014461 hasConcept C104317684 @default.
• W2155014461 hasConcept C142613039 @default.
• W2155014461 hasConcept C203014093 @default.
• W2155014461 hasConcept C204241405 @default.
• W2155014461 hasConcept C2777802930 @default.
• W2155014461 hasConcept C2778803964 @default.
• W2155014461 hasConcept C2779222958 @default.
• W2155014461 hasConcept C2780318139 @default.
• W2155014461 hasConcept C43143990 @default.
• W2155014461 hasConcept C55493867 @default.
• W2155014461 hasConcept C59822182 @default.
• W2155014461 hasConcept C86803240 @default.
• W2155014461 hasConcept C89423630 @default.
• W2155014461 hasConceptScore W2155014461C104317684 @default.
• W2155014461 hasConceptScore W2155014461C142613039 @default.
• W2155014461 hasConceptScore W2155014461C203014093 @default.
• W2155014461 hasConceptScore W2155014461C204241405 @default.
• W2155014461 hasConceptScore W2155014461C2777802930 @default.
• W2155014461 hasConceptScore W2155014461C2778803964 @default.
• W2155014461 hasConceptScore W2155014461C2779222958 @default.
• W2155014461 hasConceptScore W2155014461C2780318139 @default.
• W2155014461 hasConceptScore W2155014461C43143990 @default.
• W2155014461 hasConceptScore W2155014461C55493867 @default.
• W2155014461 hasConceptScore W2155014461C59822182 @default.
• W2155014461 hasConceptScore W2155014461C86803240 @default.
• W2155014461 hasConceptScore W2155014461C89423630 @default.
• W2155014461 hasIssue "4" @default.
• W2155014461 hasLocation W21550144611 @default.
• W2155014461 hasLocation W21550144612 @default.
• W2155014461 hasOpenAccess W2155014461 @default.
• W2155014461 hasPrimaryLocation W21550144611 @default.
• W2155014461 hasRelatedWork W1487684114 @default.
• W2155014461 hasRelatedWork W1531234934 @default.
• W2155014461 hasRelatedWork W1968633937 @default.
• W2155014461 hasRelatedWork W1986652539 @default.

• next