Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155018885> ?p ?o ?g. }
- W2155018885 endingPage "82" @default.
- W2155018885 startingPage "74" @default.
- W2155018885 abstract "Because persistent tumor necrosis factor (TNF)-alpha activation may play a pathogenic role in human immunodeficiency virus infection, TNF component levels were assessed over 78 weeks in plasma and peripheral blood mononuclear cells (PBMC) during highly active antiretroviral therapy (HAART) in 40 HIV-infected patients. HAART induced a significant decline in plasma levels of TNF-alpha and soluble TNF receptors and was associated with a fall in the abnormally increased unstimulated and a rise in the abnormally low Mycobacterium avium complex-purified-protein derivative-stimulated TNF-alpha released from PBMC. However, concentrations of these TNF components were not normalized. Patients with virologic and immunologic treatment failure after 52 weeks had higher levels of several TNF components than other patients early after initiation of therapy, also during periods with adequate virologic response. Although TNF components significantly decreased during HAART, these results support data indicating that full immunologic normalization is not achieved during such therapy. The persistent activation of the TNF system in a subgroup of persons may be involved in treatment failure." @default.
- W2155018885 created "2016-06-24" @default.
- W2155018885 creator A5002992958 @default.
- W2155018885 creator A5013106012 @default.
- W2155018885 creator A5031006818 @default.
- W2155018885 creator A5065042459 @default.
- W2155018885 creator A5069145196 @default.
- W2155018885 creator A5070064012 @default.
- W2155018885 creator A5076836210 @default.
- W2155018885 creator A5087535749 @default.
- W2155018885 date "1999-01-01" @default.
- W2155018885 modified "2023-10-18" @default.
- W2155018885 title "Tumor Necrosis Factor (TNF) System Levels in Human Immunodeficiency Virus–Infected Patients during Highly Active Antiretroviral Therapy: Persistent TNF Activation Is Associated with Virologic and Immunologic Treatment Failure" @default.
- W2155018885 cites W1438513550 @default.
- W2155018885 cites W1519144004 @default.
- W2155018885 cites W1538245603 @default.
- W2155018885 cites W1646511677 @default.
- W2155018885 cites W1691371551 @default.
- W2155018885 cites W1835910353 @default.
- W2155018885 cites W1969415662 @default.
- W2155018885 cites W1970646683 @default.
- W2155018885 cites W1980261927 @default.
- W2155018885 cites W1982448824 @default.
- W2155018885 cites W1984501809 @default.
- W2155018885 cites W1986754778 @default.
- W2155018885 cites W1990702656 @default.
- W2155018885 cites W1996168633 @default.
- W2155018885 cites W2002376988 @default.
- W2155018885 cites W2007149482 @default.
- W2155018885 cites W2008383946 @default.
- W2155018885 cites W2020855812 @default.
- W2155018885 cites W2021367723 @default.
- W2155018885 cites W2022852420 @default.
- W2155018885 cites W2027337589 @default.
- W2155018885 cites W2029223860 @default.
- W2155018885 cites W2043181035 @default.
- W2155018885 cites W2049947898 @default.
- W2155018885 cites W2055591417 @default.
- W2155018885 cites W2063205690 @default.
- W2155018885 cites W2075699405 @default.
- W2155018885 cites W2077911026 @default.
- W2155018885 cites W2099644089 @default.
- W2155018885 cites W2116014786 @default.
- W2155018885 cites W2116258000 @default.
- W2155018885 cites W2124457138 @default.
- W2155018885 cites W2134500402 @default.
- W2155018885 cites W2139894498 @default.
- W2155018885 cites W2147071499 @default.
- W2155018885 cites W2155889848 @default.
- W2155018885 cites W2156890490 @default.
- W2155018885 cites W2167644155 @default.
- W2155018885 cites W2339219218 @default.
- W2155018885 cites W2339827976 @default.
- W2155018885 cites W2342943125 @default.
- W2155018885 cites W3102208984 @default.
- W2155018885 doi "https://doi.org/10.1086/314572" @default.
- W2155018885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9841825" @default.
- W2155018885 hasPublicationYear "1999" @default.
- W2155018885 type Work @default.
- W2155018885 sameAs 2155018885 @default.
- W2155018885 citedByCount "149" @default.
- W2155018885 countsByYear W21550188852012 @default.
- W2155018885 countsByYear W21550188852013 @default.
- W2155018885 countsByYear W21550188852014 @default.
- W2155018885 countsByYear W21550188852015 @default.
- W2155018885 countsByYear W21550188852016 @default.
- W2155018885 countsByYear W21550188852017 @default.
- W2155018885 countsByYear W21550188852018 @default.
- W2155018885 countsByYear W21550188852019 @default.
- W2155018885 countsByYear W21550188852021 @default.
- W2155018885 countsByYear W21550188852022 @default.
- W2155018885 crossrefType "journal-article" @default.
- W2155018885 hasAuthorship W2155018885A5002992958 @default.
- W2155018885 hasAuthorship W2155018885A5013106012 @default.
- W2155018885 hasAuthorship W2155018885A5031006818 @default.
- W2155018885 hasAuthorship W2155018885A5065042459 @default.
- W2155018885 hasAuthorship W2155018885A5069145196 @default.
- W2155018885 hasAuthorship W2155018885A5070064012 @default.
- W2155018885 hasAuthorship W2155018885A5076836210 @default.
- W2155018885 hasAuthorship W2155018885A5087535749 @default.
- W2155018885 hasBestOaLocation W21550188851 @default.
- W2155018885 hasConcept C137061746 @default.
- W2155018885 hasConcept C159047783 @default.
- W2155018885 hasConcept C17991360 @default.
- W2155018885 hasConcept C202751555 @default.
- W2155018885 hasConcept C203014093 @default.
- W2155018885 hasConcept C2522874641 @default.
- W2155018885 hasConcept C2780648854 @default.
- W2155018885 hasConcept C55493867 @default.
- W2155018885 hasConcept C71924100 @default.
- W2155018885 hasConcept C86803240 @default.
- W2155018885 hasConceptScore W2155018885C137061746 @default.
- W2155018885 hasConceptScore W2155018885C159047783 @default.
- W2155018885 hasConceptScore W2155018885C17991360 @default.
- W2155018885 hasConceptScore W2155018885C202751555 @default.
- W2155018885 hasConceptScore W2155018885C203014093 @default.
- W2155018885 hasConceptScore W2155018885C2522874641 @default.
- W2155018885 hasConceptScore W2155018885C2780648854 @default.