FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155057188> ?p ?o ?g. }

• W2155057188 abstract "Conventional step&shoot intensity modulated radio therapy (IMRT) approaches potentially lead to treatment plans with high numbers of segments and monitor units (MU) and, therefore, could be time consuming at the linear accelerator. Direct optimization methods are able to reduce the complexity without degrading the quality of the plan. The aim of this study is the evaluation of different IMRT approaches at standardized conditions for head and neck tumors.For 27 patients with carcinomas in the head and neck region a planning study with a 2-step-IMRT system (KonRad), a direct optimization system (Panther DAO) and a mixture of both approaches (MasterPlan DSS) was created. In order to avoid different prescription doses for boost volumes a simple standardization was realized. The dose was downscaled to 50 Gy to the planning target volume (PTV) which included the primary tumor as well as the bilateral lymphatic drainage (cervical and supraclavicular). Dose restrictions for the organs at risk (OAR) were downscaled to this prescription from high dose concepts up to 72 Gy. Those limits were defined as planning objectives while reaching definable PTV coverage with a standardized field setup. The parameters were evaluated from the corresponding dose volume histogram (DVH). Special attention was paid to the efficiency of the method, measured by means of calculated MU and required segments. Statistical tests of significance were applied to quantify the differences between the evaluated systems.PTV coverage for all systems in terms of V90% and V95% fell short of the requested 100% and 95%, respectively, but were still acceptable (range: 98.7% to 99.1% and 94.2% to 94.7%). Overall for OAR sparing and the burden of healthy tissue with low doses no technique was superior for all evaluated parameters. Differences were found for the number of segments where the direct optimization systems generated less segments. Lowest average numbers of MU were 308 by Panther DAO calculated for 2 Gy fractions. Based on these findings the treatment time at the linear accelerator is the lowest for Panther DAO.All IMRT approaches implemented in the different treatment planning systems (TPS) generated clinically acceptable and comparable plans. No superior system in terms of PTV coverage and OAR sparing was found. Major differences in efficiency of the method in terms of calculated MU and treatment times were found." @default.
• W2155057188 created "2016-06-24" @default.
• W2155057188 creator A5006343705 @default.
• W2155057188 creator A5027698958 @default.
• W2155057188 creator A5042811051 @default.
• W2155057188 creator A5069614255 @default.
• W2155057188 date "2012-01-23" @default.
• W2155057188 modified "2023-10-14" @default.
• W2155057188 title "The impact of direct aperture optimization on plan quality and efficiency in complex head and neck IMRT" @default.
• W2155057188 cites W1559319238 @default.
• W2155057188 cites W1969144335 @default.
• W2155057188 cites W1970894152 @default.
• W2155057188 cites W1971904425 @default.
• W2155057188 cites W1991566473 @default.
• W2155057188 cites W1992642392 @default.
• W2155057188 cites W2008700492 @default.
• W2155057188 cites W2012354979 @default.
• W2155057188 cites W2036282507 @default.
• W2155057188 cites W2041147095 @default.
• W2155057188 cites W2046701188 @default.
• W2155057188 cites W2067834214 @default.
• W2155057188 cites W2071833455 @default.
• W2155057188 cites W2091603229 @default.
• W2155057188 cites W2121107039 @default.
• W2155057188 cites W2141540810 @default.
• W2155057188 cites W2151317678 @default.
• W2155057188 doi "https://doi.org/10.1186/1748-717x-7-7" @default.
• W2155057188 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3275495" @default.
• W2155057188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22269088" @default.
• W2155057188 hasPublicationYear "2012" @default.
• W2155057188 type Work @default.
• W2155057188 sameAs 2155057188 @default.
• W2155057188 citedByCount "4" @default.
• W2155057188 countsByYear W21550571882012 @default.
• W2155057188 countsByYear W21550571882014 @default.
• W2155057188 crossrefType "journal-article" @default.
• W2155057188 hasAuthorship W2155057188A5006343705 @default.
• W2155057188 hasAuthorship W2155057188A5027698958 @default.
• W2155057188 hasAuthorship W2155057188A5042811051 @default.
• W2155057188 hasAuthorship W2155057188A5069614255 @default.
• W2155057188 hasBestOaLocation W21550571881 @default.
• W2155057188 hasConcept C106436119 @default.
• W2155057188 hasConcept C126838900 @default.
• W2155057188 hasConcept C141071460 @default.
• W2155057188 hasConcept C142724271 @default.
• W2155057188 hasConcept C201645570 @default.
• W2155057188 hasConcept C2778618615 @default.
• W2155057188 hasConcept C2989005 @default.
• W2155057188 hasConcept C3018411727 @default.
• W2155057188 hasConcept C509974204 @default.
• W2155057188 hasConcept C71924100 @default.
• W2155057188 hasConceptScore W2155057188C106436119 @default.
• W2155057188 hasConceptScore W2155057188C126838900 @default.
• W2155057188 hasConceptScore W2155057188C141071460 @default.
• W2155057188 hasConceptScore W2155057188C142724271 @default.
• W2155057188 hasConceptScore W2155057188C201645570 @default.
• W2155057188 hasConceptScore W2155057188C2778618615 @default.
• W2155057188 hasConceptScore W2155057188C2989005 @default.
• W2155057188 hasConceptScore W2155057188C3018411727 @default.
• W2155057188 hasConceptScore W2155057188C509974204 @default.
• W2155057188 hasConceptScore W2155057188C71924100 @default.
• W2155057188 hasIssue "1" @default.
• W2155057188 hasLocation W21550571881 @default.
• W2155057188 hasLocation W21550571882 @default.
• W2155057188 hasLocation W21550571883 @default.
• W2155057188 hasLocation W21550571884 @default.
• W2155057188 hasOpenAccess W2155057188 @default.
• W2155057188 hasPrimaryLocation W21550571881 @default.
• W2155057188 hasRelatedWork W1692233864 @default.
• W2155057188 hasRelatedWork W2363834598 @default.
• W2155057188 hasRelatedWork W2466377223 @default.
• W2155057188 hasRelatedWork W2741951020 @default.
• W2155057188 hasRelatedWork W2911874346 @default.
• W2155057188 hasRelatedWork W3138304378 @default.
• W2155057188 hasRelatedWork W4237240905 @default.
• W2155057188 hasRelatedWork W4250374586 @default.
• W2155057188 hasRelatedWork W563463963 @default.
• W2155057188 hasRelatedWork W935391112 @default.
• W2155057188 hasVolume "7" @default.
• W2155057188 isParatext "false" @default.
• W2155057188 isRetracted "false" @default.
• W2155057188 magId "2155057188" @default.
• W2155057188 workType "article" @default.