Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155070282> ?p ?o ?g. }
- W2155070282 endingPage "952" @default.
- W2155070282 startingPage "941" @default.
- W2155070282 abstract "After antigen capture, dendritic cells (DC) migrate into T cell-rich areas of secondary lymphoid organs, where they induce T cell activation, that subsequently drives B cell activation. Here, we investigate whether DC, generated in vitro, can directly modulate B cell responses, using CD40L-transfected L cells as surrogate activated T cells. DC, through the production of soluble mediators, stimulated by 3- to 6-fold the proliferation and subsequent recovery of B cells. Furthermore, after CD40 ligation, DC enhanced by 30-300-fold the secretion of IgG and IgA by sIgD- B cells (essentially memory B cells). In the presence of DC, naive sIgD+ B cells produced, in response to interleukin-2, large amounts of IgM. Thus, in addition to activating naive T cells in the extrafollicular areas of secondary lymphoid organs, DC may directly modulate B cell growth and differentiation." @default.
- W2155070282 created "2016-06-24" @default.
- W2155070282 creator A5001942902 @default.
- W2155070282 creator A5002962815 @default.
- W2155070282 creator A5014995114 @default.
- W2155070282 creator A5025970784 @default.
- W2155070282 creator A5027596750 @default.
- W2155070282 creator A5028065894 @default.
- W2155070282 creator A5044500829 @default.
- W2155070282 creator A5069641539 @default.
- W2155070282 date "1997-03-03" @default.
- W2155070282 modified "2023-10-18" @default.
- W2155070282 title "Dendritic Cells Enhance Growth and Differentiation of CD40-activated B Lymphocytes" @default.
- W2155070282 cites W146570405 @default.
- W2155070282 cites W1511991731 @default.
- W2155070282 cites W1512002142 @default.
- W2155070282 cites W1535574970 @default.
- W2155070282 cites W1547027512 @default.
- W2155070282 cites W1558688513 @default.
- W2155070282 cites W1966408842 @default.
- W2155070282 cites W1966578377 @default.
- W2155070282 cites W1976045232 @default.
- W2155070282 cites W1989055057 @default.
- W2155070282 cites W1989692667 @default.
- W2155070282 cites W1989741304 @default.
- W2155070282 cites W1998887059 @default.
- W2155070282 cites W1998895943 @default.
- W2155070282 cites W2007289040 @default.
- W2155070282 cites W2014513955 @default.
- W2155070282 cites W2017140462 @default.
- W2155070282 cites W2019546595 @default.
- W2155070282 cites W2036867505 @default.
- W2155070282 cites W2039409588 @default.
- W2155070282 cites W2040019425 @default.
- W2155070282 cites W2050127536 @default.
- W2155070282 cites W2051658534 @default.
- W2155070282 cites W2058050336 @default.
- W2155070282 cites W2060382742 @default.
- W2155070282 cites W2065712492 @default.
- W2155070282 cites W2069078625 @default.
- W2155070282 cites W2078393591 @default.
- W2155070282 cites W2085593429 @default.
- W2155070282 cites W2091085026 @default.
- W2155070282 cites W2111695773 @default.
- W2155070282 cites W2119338471 @default.
- W2155070282 cites W2121236896 @default.
- W2155070282 cites W2121716202 @default.
- W2155070282 cites W2124010557 @default.
- W2155070282 cites W2133951067 @default.
- W2155070282 cites W2138706726 @default.
- W2155070282 cites W2139573199 @default.
- W2155070282 cites W2147715156 @default.
- W2155070282 cites W2148647317 @default.
- W2155070282 cites W2155229523 @default.
- W2155070282 cites W2161243339 @default.
- W2155070282 cites W2167598714 @default.
- W2155070282 cites W2172658766 @default.
- W2155070282 cites W2177327503 @default.
- W2155070282 doi "https://doi.org/10.1084/jem.185.5.941" @default.
- W2155070282 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2196162" @default.
- W2155070282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9120400" @default.
- W2155070282 hasPublicationYear "1997" @default.
- W2155070282 type Work @default.
- W2155070282 sameAs 2155070282 @default.
- W2155070282 citedByCount "289" @default.
- W2155070282 countsByYear W21550702822012 @default.
- W2155070282 countsByYear W21550702822013 @default.
- W2155070282 countsByYear W21550702822014 @default.
- W2155070282 countsByYear W21550702822015 @default.
- W2155070282 countsByYear W21550702822016 @default.
- W2155070282 countsByYear W21550702822017 @default.
- W2155070282 countsByYear W21550702822018 @default.
- W2155070282 countsByYear W21550702822019 @default.
- W2155070282 countsByYear W21550702822020 @default.
- W2155070282 countsByYear W21550702822022 @default.
- W2155070282 crossrefType "journal-article" @default.
- W2155070282 hasAuthorship W2155070282A5001942902 @default.
- W2155070282 hasAuthorship W2155070282A5002962815 @default.
- W2155070282 hasAuthorship W2155070282A5014995114 @default.
- W2155070282 hasAuthorship W2155070282A5025970784 @default.
- W2155070282 hasAuthorship W2155070282A5027596750 @default.
- W2155070282 hasAuthorship W2155070282A5028065894 @default.
- W2155070282 hasAuthorship W2155070282A5044500829 @default.
- W2155070282 hasAuthorship W2155070282A5069641539 @default.
- W2155070282 hasBestOaLocation W21550702821 @default.
- W2155070282 hasConcept C104317684 @default.
- W2155070282 hasConcept C129374314 @default.
- W2155070282 hasConcept C134018914 @default.
- W2155070282 hasConcept C145558887 @default.
- W2155070282 hasConcept C147483822 @default.
- W2155070282 hasConcept C148738053 @default.
- W2155070282 hasConcept C149532602 @default.
- W2155070282 hasConcept C153911025 @default.
- W2155070282 hasConcept C154317977 @default.
- W2155070282 hasConcept C159654299 @default.
- W2155070282 hasConcept C200180986 @default.
- W2155070282 hasConcept C202751555 @default.
- W2155070282 hasConcept C203014093 @default.