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- W2155081670 abstract "Prostate cancer is the second most common cause of cancer and the sixth leading cause of cancer death among men worldwide. While localized prostate cancer can be cured, advanced and metastatic prostate cancer remains a significant therapeutic challenge. Malignant transformation is associated with important modifications of the cellular glycosylation profile, and it is postulated that these changes have a considerable relevance for tumor biology. Metastasis is a multiphasic process that encompasses angiogenesis, the spread of tumor cells and their growth at distant sites from the primary tumor location. Recognition of glycoconjugates by galectins, among other lectins, plays a fundamental role in the metastatic spread, tumor immune escape and the neovascularization process. Particularly in prostate cancer, both carbohydrates and galectins have been implicated in many cellular processes such as proliferation, apoptosis, migration and invasion. However, a limited number of studies assessed their potential implications in the induction of metastasis in prostate cancer patients or in animal models. Moreover, the role of galectin–glycan interactions in vivo still remains poorly understood; concerted effort should thus be made in order to shed some light on this question. This review summarizes current evidence on both the expression and role of glycans and galectins in prostate cancer, particularly turning our attention to the angiogenic and metastatic processes." @default.
- W2155081670 created "2016-06-24" @default.
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- W2155081670 date "2014-06-16" @default.
- W2155081670 modified "2023-10-07" @default.
- W2155081670 title "Glycans and galectins in prostate cancer biology, angiogenesis and metastasis" @default.
- W2155081670 cites W116085590 @default.
- W2155081670 cites W1276003021 @default.
- W2155081670 cites W1483678763 @default.
- W2155081670 cites W1740737174 @default.
- W2155081670 cites W1776996595 @default.
- W2155081670 cites W1848635928 @default.
- W2155081670 cites W1967347349 @default.
- W2155081670 cites W1967641344 @default.
- W2155081670 cites W1967989660 @default.
- W2155081670 cites W1968014420 @default.
- W2155081670 cites W1969592341 @default.
- W2155081670 cites W1971377557 @default.
- W2155081670 cites W1971411781 @default.
- W2155081670 cites W1975817404 @default.
- W2155081670 cites W1975949520 @default.
- W2155081670 cites W1980035883 @default.
- W2155081670 cites W1980804493 @default.
- W2155081670 cites W1982095943 @default.
- W2155081670 cites W1992690905 @default.
- W2155081670 cites W1994466260 @default.
- W2155081670 cites W1995878243 @default.
- W2155081670 cites W2000671183 @default.
- W2155081670 cites W2003128631 @default.
- W2155081670 cites W2007058937 @default.
- W2155081670 cites W2010016099 @default.
- W2155081670 cites W2010896383 @default.
- W2155081670 cites W201136091 @default.
- W2155081670 cites W2013180631 @default.
- W2155081670 cites W2015306991 @default.
- W2155081670 cites W2017544831 @default.
- W2155081670 cites W2018067447 @default.
- W2155081670 cites W2018543114 @default.
- W2155081670 cites W2024525959 @default.
- W2155081670 cites W2029781784 @default.
- W2155081670 cites W2038361233 @default.
- W2155081670 cites W2042180369 @default.
- W2155081670 cites W2046148841 @default.
- W2155081670 cites W2046229657 @default.
- W2155081670 cites W2051599525 @default.
- W2155081670 cites W2063095520 @default.
- W2155081670 cites W2069883829 @default.
- W2155081670 cites W2071071778 @default.
- W2155081670 cites W2071949511 @default.
- W2155081670 cites W2073874933 @default.
- W2155081670 cites W2079492290 @default.
- W2155081670 cites W2080439368 @default.
- W2155081670 cites W2083260383 @default.
- W2155081670 cites W2084811810 @default.
- W2155081670 cites W2088373848 @default.
- W2155081670 cites W2093626739 @default.
- W2155081670 cites W2094999590 @default.
- W2155081670 cites W2096444752 @default.
- W2155081670 cites W2098305726 @default.
- W2155081670 cites W2098483493 @default.
- W2155081670 cites W2099423097 @default.
- W2155081670 cites W2100213659 @default.
- W2155081670 cites W2100331658 @default.
- W2155081670 cites W2101854789 @default.
- W2155081670 cites W2102865930 @default.
- W2155081670 cites W2102896820 @default.
- W2155081670 cites W2106787323 @default.
- W2155081670 cites W2108244696 @default.
- W2155081670 cites W2110493163 @default.
- W2155081670 cites W2118300139 @default.
- W2155081670 cites W2118991367 @default.
- W2155081670 cites W2120292596 @default.
- W2155081670 cites W2130574102 @default.
- W2155081670 cites W2134443544 @default.
- W2155081670 cites W2137241444 @default.
- W2155081670 cites W2139177238 @default.
- W2155081670 cites W2139368593 @default.
- W2155081670 cites W2142813467 @default.
- W2155081670 cites W2153389408 @default.
- W2155081670 cites W2157172418 @default.
- W2155081670 cites W2158008391 @default.
- W2155081670 cites W2167147051 @default.
- W2155081670 cites W2168355000 @default.
- W2155081670 cites W2188713841 @default.
- W2155081670 cites W2465336680 @default.
- W2155081670 cites W4243173488 @default.
- W2155081670 cites W4361741424 @default.
- W2155081670 doi "https://doi.org/10.1093/glycob/cwu055" @default.
- W2155081670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24939371" @default.
- W2155081670 hasPublicationYear "2014" @default.
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