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- W2155109807 abstract "High-density lipoproteins (HDL) play a major protective role against the development of coronary artery disease. Phospholipid transfer protein (PLTP) is a main factor regulating the size and composition of HDL in the circulation and plays an important role in controlling plasma HDL levels. This is achieved via both the phospholipid transfer activity of PLTP and its capability to cause HDL conversion. The present review focuses on the impact of PLTP on HDL metabolism. The basic characteristics and structure of the PLTP protein are described. The two main functions of PLTP, PLTP-mediated phospholipid transfer and HDL conversion are reviewed, and the mechanisms and control, as well as the physiological significance of these processes are discussed. The relationship between PLTP and the related cholesteryl ester transfer protein (CETP) is reviewed. Thereafter other functions of PLTP are recapitulated: the ability of PLTP to transfer cholesterol, alpha-tocopherol and lipopolysaccharide (LPS), and the suggested involvement of PLTP in cellular cholesterol traffic. The discussion on PLTP activity and mass in (patho)physiological settings includes new data on the presence of two forms of PLTP in the circulation, one catalytically active and the other inactive. Finally, future directions for PLTP research are outlined." @default.
- W2155109807 created "2016-06-24" @default.
- W2155109807 creator A5006496770 @default.
- W2155109807 creator A5016356740 @default.
- W2155109807 creator A5043534256 @default.
- W2155109807 creator A5075525029 @default.
- W2155109807 date "2001-04-01" @default.
- W2155109807 modified "2023-09-23" @default.
- W2155109807 title "The impact of phospholipid transfer protein (PLTP) on HDL metabolism" @default.
- W2155109807 cites W1460913000 @default.
- W2155109807 cites W1487672819 @default.
- W2155109807 cites W1503868770 @default.
- W2155109807 cites W1518143332 @default.
- W2155109807 cites W1536933520 @default.
- W2155109807 cites W1567784298 @default.
- W2155109807 cites W1577273492 @default.
- W2155109807 cites W1591670239 @default.
- W2155109807 cites W1607399348 @default.
- W2155109807 cites W165878460 @default.
- W2155109807 cites W1705999641 @default.
- W2155109807 cites W1832115605 @default.
- W2155109807 cites W1860908381 @default.
- W2155109807 cites W1878627435 @default.
- W2155109807 cites W1884837952 @default.
- W2155109807 cites W1910286451 @default.
- W2155109807 cites W1958226015 @default.
- W2155109807 cites W1963337827 @default.
- W2155109807 cites W1964304065 @default.
- W2155109807 cites W1965707506 @default.
- W2155109807 cites W1968121249 @default.
- W2155109807 cites W1970097948 @default.
- W2155109807 cites W1975798465 @default.
- W2155109807 cites W1981136913 @default.
- W2155109807 cites W1988334797 @default.
- W2155109807 cites W1997026063 @default.
- W2155109807 cites W2001158939 @default.
- W2155109807 cites W2001507316 @default.
- W2155109807 cites W2006486628 @default.
- W2155109807 cites W2009026141 @default.
- W2155109807 cites W2010828166 @default.
- W2155109807 cites W2011656212 @default.
- W2155109807 cites W2011833777 @default.
- W2155109807 cites W2013313335 @default.
- W2155109807 cites W2014683041 @default.
- W2155109807 cites W2016445095 @default.
- W2155109807 cites W2017203485 @default.
- W2155109807 cites W2018606939 @default.
- W2155109807 cites W2018907365 @default.
- W2155109807 cites W2022663083 @default.
- W2155109807 cites W2024779419 @default.
- W2155109807 cites W2025382682 @default.
- W2155109807 cites W2027089681 @default.
- W2155109807 cites W2028653252 @default.
- W2155109807 cites W2028839767 @default.
- W2155109807 cites W2029157767 @default.
- W2155109807 cites W2031886869 @default.
- W2155109807 cites W2032413868 @default.
- W2155109807 cites W2034451538 @default.
- W2155109807 cites W2035379131 @default.
- W2155109807 cites W2036700661 @default.
- W2155109807 cites W2039859468 @default.
- W2155109807 cites W2041242656 @default.
- W2155109807 cites W2041417616 @default.
- W2155109807 cites W2041501956 @default.
- W2155109807 cites W2042593570 @default.
- W2155109807 cites W2044343704 @default.
- W2155109807 cites W2045763953 @default.
- W2155109807 cites W2046413271 @default.
- W2155109807 cites W2047330360 @default.
- W2155109807 cites W2051455463 @default.
- W2155109807 cites W2056576549 @default.
- W2155109807 cites W2060558017 @default.
- W2155109807 cites W2063596708 @default.
- W2155109807 cites W2068813676 @default.
- W2155109807 cites W2070169867 @default.
- W2155109807 cites W2071511516 @default.
- W2155109807 cites W2071630426 @default.
- W2155109807 cites W2074515617 @default.
- W2155109807 cites W2078574629 @default.
- W2155109807 cites W2078837478 @default.
- W2155109807 cites W2079469669 @default.
- W2155109807 cites W2080164474 @default.
- W2155109807 cites W2082873765 @default.
- W2155109807 cites W2083392018 @default.
- W2155109807 cites W2086034638 @default.
- W2155109807 cites W2090151321 @default.
- W2155109807 cites W2098835137 @default.
- W2155109807 cites W2100225528 @default.
- W2155109807 cites W2112046710 @default.
- W2155109807 cites W2113242078 @default.
- W2155109807 cites W2113411292 @default.
- W2155109807 cites W2113504642 @default.
- W2155109807 cites W2115578564 @default.
- W2155109807 cites W2116432245 @default.
- W2155109807 cites W2123850490 @default.
- W2155109807 cites W2125378113 @default.
- W2155109807 cites W2128986402 @default.
- W2155109807 cites W2130245663 @default.