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• W2155133695 abstract "Evidence suggests that gonadal hormones can modulate sensitivity to nociceptive stimuli and opioid antinociception. However, cross-study comparisons addressing the nature of this modulation have been complicated by a number of methodologic factors, including the use of different rodent strains and opioids. The present study examined the influence of estrous cycle and gonadal hormone depletion (ovariectomy) on thermal nociception and opioid antinociception in female F344, Lewis, Long Evans, and Wistar rats. Estrous cycle-dependent differences in nociceptive sensitivity were not observed in any of the strains. Ovariectomy decreased nociceptive sensitivity relative to their intact female counterparts. In normal cycling females, morphine and buprenorphine were generally most potent in metestrus and proestrus and least potent in estrus. The magnitude of these differences was consistently larger with buprenorphine. Ovariectomy increased the antinociceptive potency of morphine and buprenorphine, with this effect also being larger with buprenorphine. These data suggest that in adult females of a number of rat strains, estrous cycle and gonadal hormone depletion modulate the antinociceptive potency of opioids, with the magnitude of this effect being dependent on the type of opioid. In contrast, depletion of gonadal hormones, but not estrous cycle, modulates thermal nociceptive sensitivity in adult female rats. Perspective Gonadal hormones influence opioid antinociception, and this effect is apparent across different genetic backgrounds. These results suggest that the phase of the menstrual cycle might alter the effectiveness of certain opioids administered to relieve pain in women." @default.
• W2155133695 created "2016-06-24" @default.
• W2155133695 creator A5002850882 @default.
• W2155133695 creator A5068312145 @default.
• W2155133695 creator A5080403024 @default.
• W2155133695 date "2005-06-01" @default.
• W2155133695 modified "2023-10-14" @default.
• W2155133695 title "Influence of Estrous Cycle and Gonadal Hormone Depletion on Nociception and Opioid Antinociception in Female Rats of Four Strains" @default.
• W2155133695 cites W1968001086 @default.
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• W2155133695 cites W1974371245 @default.
• W2155133695 cites W1975986172 @default.
• W2155133695 cites W1979441699 @default.
• W2155133695 cites W1980674774 @default.
• W2155133695 cites W1981680359 @default.
• W2155133695 cites W1982891583 @default.
• W2155133695 cites W1983094530 @default.
• W2155133695 cites W1985992519 @default.
• W2155133695 cites W1992764757 @default.
• W2155133695 cites W1993136139 @default.
• W2155133695 cites W1998743905 @default.
• W2155133695 cites W2002168476 @default.
• W2155133695 cites W2002956999 @default.
• W2155133695 cites W2014786081 @default.
• W2155133695 cites W2015508347 @default.
• W2155133695 cites W2016293007 @default.
• W2155133695 cites W2017336787 @default.
• W2155133695 cites W2018364764 @default.
• W2155133695 cites W2021604137 @default.
• W2155133695 cites W2023131011 @default.
• W2155133695 cites W2024538851 @default.
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• W2155133695 cites W2026982851 @default.
• W2155133695 cites W2028288909 @default.
• W2155133695 cites W2029995831 @default.
• W2155133695 cites W2033515676 @default.
• W2155133695 cites W2034009099 @default.
• W2155133695 cites W2035106355 @default.
• W2155133695 cites W2036370071 @default.
• W2155133695 cites W2036600146 @default.
• W2155133695 cites W2036732725 @default.
• W2155133695 cites W2040457846 @default.
• W2155133695 cites W2040974460 @default.
• W2155133695 cites W2044013974 @default.
• W2155133695 cites W2045979065 @default.
• W2155133695 cites W2046732597 @default.
• W2155133695 cites W2049737322 @default.
• W2155133695 cites W2051341512 @default.
• W2155133695 cites W2055173362 @default.
• W2155133695 cites W2055471067 @default.
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• W2155133695 cites W2067115675 @default.
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• W2155133695 cites W2073611645 @default.
• W2155133695 cites W2076187030 @default.
• W2155133695 cites W2077483410 @default.
• W2155133695 cites W2077968281 @default.
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• W2155133695 cites W2084230118 @default.
• W2155133695 cites W2087454739 @default.
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• W2155133695 cites W2101395256 @default.
• W2155133695 cites W2120907839 @default.
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• W2155133695 doi "https://doi.org/10.1016/j.jpain.2005.01.354" @default.
• W2155133695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15943959" @default.
• W2155133695 hasPublicationYear "2005" @default.
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