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• W2155138847 endingPage "692" @default.
• W2155138847 startingPage "679" @default.
• W2155138847 abstract "Deficiencies of nutrients such as amino acids, vitamins, lipids, and trace elements during gestation and early infanthood have strong deleterious effects on the development of the limbic system; these effects may be irreversible, even when adequate supplementation is provided at later developmental stages. Recent advances in the neurochemistry of biometals are increasingly establishing the roles of the trace elements iron, copper, zinc, and selenium in a variety of cell functions and are providing insight into the repercussions of deficiencies and excesses of these elements on the development of the central nervous system, especially the limbic system. The limbic system comprises diverse areas with high metabolic demands and differential storage of iron, copper, zinc, and selenium. This review summarizes available evidence suggesting the involvement of these trace elements in pathological disorders of the limbic system." @default.
• W2155138847 created "2016-06-24" @default.
• W2155138847 creator A5007864307 @default.
• W2155138847 creator A5033661150 @default.
• W2155138847 creator A5037865959 @default.
• W2155138847 creator A5048322447 @default.
• W2155138847 creator A5079188226 @default.
• W2155138847 date "2012-10-25" @default.
• W2155138847 modified "2023-09-25" @default.
• W2155138847 title "Limbic system pathologies associated with deficiencies and excesses of the trace elements iron, zinc, copper, and selenium" @default.
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