FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155148112> ?p ?o ?g. }

• W2155148112 abstract "Recent clinical and experimental evidence suggests that the spike-wave discharges (SWD) of absence seizures result from local activity within a hyperexcitable cortical region with rapid generalization through thalamocortical networks. The cortical focus is said to react more strongly to stimulation than other areas. We seek to develop a model which is in agreement with these recent experimental findings and suggest a possible explanation. In this study we extend an existing neural field model of thalamocortical interaction to account for multiple cortical regions which are connected according connectivity inferred from a clinically diagnosed epileptic patient. We stimulate at different model electrodes and investigate the resulting seizure duration. We observe that stimulation of only a small subset (11%) of model electrodes can lead to the rapid generalisation of SWD via both corticocortical and thalamocortical pathways. We find that the resulting model dynamics (seizure duration) varies significantly dependent upon the nodes stimulated and the amplitude of the stimulus. Our model indicates that heterogeneities in corticocortical connectivity could serve as a possible reason for the cortical focus and provides a platform for in silico hypothesis generation in complement to in vivo hypothesis validation." @default.
• W2155148112 created "2016-06-24" @default.
• W2155148112 creator A5010837788 @default.
• W2155148112 creator A5020252837 @default.
• W2155148112 creator A5024260303 @default.
• W2155148112 creator A5031778533 @default.
• W2155148112 creator A5044026747 @default.
• W2155148112 creator A5082613025 @default.
• W2155148112 date "2013-04-01" @default.
• W2155148112 modified "2023-09-26" @default.
• W2155148112 title "A model of stimulus induced epileptic spike-wave discharges" @default.
• W2155148112 cites W1519673444 @default.
• W2155148112 cites W1840565448 @default.
• W2155148112 cites W1874867185 @default.
• W2155148112 cites W1886118302 @default.
• W2155148112 cites W1964824984 @default.
• W2155148112 cites W1968865407 @default.
• W2155148112 cites W1981140845 @default.
• W2155148112 cites W2002388289 @default.
• W2155148112 cites W2008462638 @default.
• W2155148112 cites W2008518032 @default.
• W2155148112 cites W2014721375 @default.
• W2155148112 cites W2016354087 @default.
• W2155148112 cites W2021281924 @default.
• W2155148112 cites W2022436691 @default.
• W2155148112 cites W2029374903 @default.
• W2155148112 cites W2034931436 @default.
• W2155148112 cites W2044113523 @default.
• W2155148112 cites W2052990681 @default.
• W2155148112 cites W2063962699 @default.
• W2155148112 cites W2085297965 @default.
• W2155148112 cites W2101420429 @default.
• W2155148112 cites W2115726932 @default.
• W2155148112 cites W2123553271 @default.
• W2155148112 cites W2131582127 @default.
• W2155148112 cites W2135234927 @default.
• W2155148112 cites W2147223467 @default.
• W2155148112 cites W2155438906 @default.
• W2155148112 cites W2158343591 @default.
• W2155148112 cites W2160184536 @default.
• W2155148112 cites W2165861322 @default.
• W2155148112 cites W2167395832 @default.
• W2155148112 cites W2170246198 @default.
• W2155148112 cites W2313560363 @default.
• W2155148112 cites W2506699060 @default.
• W2155148112 doi "https://doi.org/10.1109/ccmb.2013.6609165" @default.
• W2155148112 hasPublicationYear "2013" @default.
• W2155148112 type Work @default.
• W2155148112 sameAs 2155148112 @default.
• W2155148112 citedByCount "20" @default.
• W2155148112 countsByYear W21551481122014 @default.
• W2155148112 countsByYear W21551481122016 @default.
• W2155148112 countsByYear W21551481122017 @default.
• W2155148112 countsByYear W21551481122019 @default.
• W2155148112 countsByYear W21551481122020 @default.
• W2155148112 countsByYear W21551481122022 @default.
• W2155148112 countsByYear W21551481122023 @default.
• W2155148112 crossrefType "proceedings-article" @default.
• W2155148112 hasAuthorship W2155148112A5010837788 @default.
• W2155148112 hasAuthorship W2155148112A5020252837 @default.
• W2155148112 hasAuthorship W2155148112A5024260303 @default.
• W2155148112 hasAuthorship W2155148112A5031778533 @default.
• W2155148112 hasAuthorship W2155148112A5044026747 @default.
• W2155148112 hasAuthorship W2155148112A5082613025 @default.
• W2155148112 hasBestOaLocation W21551481122 @default.
• W2155148112 hasConcept C117838684 @default.
• W2155148112 hasConcept C121332964 @default.
• W2155148112 hasConcept C15744967 @default.
• W2155148112 hasConcept C169760540 @default.
• W2155148112 hasConcept C180747234 @default.
• W2155148112 hasConcept C24998067 @default.
• W2155148112 hasConcept C2778186239 @default.
• W2155148112 hasConcept C2779918689 @default.
• W2155148112 hasConcept C2983650178 @default.
• W2155148112 hasConcept C41008148 @default.
• W2155148112 hasConcept C522805319 @default.
• W2155148112 hasConceptScore W2155148112C117838684 @default.
• W2155148112 hasConceptScore W2155148112C121332964 @default.
• W2155148112 hasConceptScore W2155148112C15744967 @default.
• W2155148112 hasConceptScore W2155148112C169760540 @default.
• W2155148112 hasConceptScore W2155148112C180747234 @default.
• W2155148112 hasConceptScore W2155148112C24998067 @default.
• W2155148112 hasConceptScore W2155148112C2778186239 @default.
• W2155148112 hasConceptScore W2155148112C2779918689 @default.
• W2155148112 hasConceptScore W2155148112C2983650178 @default.
• W2155148112 hasConceptScore W2155148112C41008148 @default.
• W2155148112 hasConceptScore W2155148112C522805319 @default.
• W2155148112 hasLocation W21551481121 @default.
• W2155148112 hasLocation W21551481122 @default.
• W2155148112 hasLocation W21551481123 @default.
• W2155148112 hasOpenAccess W2155148112 @default.
• W2155148112 hasPrimaryLocation W21551481121 @default.
• W2155148112 hasRelatedWork W1986274952 @default.
• W2155148112 hasRelatedWork W2012315399 @default.
• W2155148112 hasRelatedWork W2027159176 @default.
• W2155148112 hasRelatedWork W2081202972 @default.
• W2155148112 hasRelatedWork W2151134065 @default.
• W2155148112 hasRelatedWork W2945442807 @default.
• W2155148112 hasRelatedWork W2951735952 @default.
• W2155148112 hasRelatedWork W3205306594 @default.

• next