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- W2155176886 abstract "The stem extract of Tephrosia purpurea showed antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains of Plasmodium falciparum with IC50 values of 10.47 ± 2.22 μg/ml and 12.06 ± 2.54 μg/ml, respectively. A new prenylated flavone, named terpurinflavone, along with the known compounds lanceolatin A, (−)-semiglabrin and lanceolatin B have been isolated from this extract. The new compound, terpurinflavone, showed the highest antiplasmodial activity with IC50 values of 3.12 ± 0.28 μM (D6) and 6.26 ± 2.66 μM (W2). The structures were determined on the basis of spectroscopic evidence." @default.
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- W2155176886 date "2011-06-01" @default.
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- W2155176886 title "Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea" @default.
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- W2155176886 doi "https://doi.org/10.1016/j.phytol.2011.02.010" @default.
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