FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155178437> ?p ?o ?g. }

• W2155178437 endingPage "755" @default.
• W2155178437 startingPage "748" @default.
• W2155178437 abstract "Colonic tumours were induced in Wistar rats using 12 consecutive subcutaneous injections of azoxymethane at a dose of 10 mg/kg/week. Pairs of rats were killed at five weekly intervals after initial injection until 25 weeks. Colonic mucosa was sampled from five standard areas along the length of the colon and examined by both scanning electron microscopy and conventional light microscopy. The crypt cell production rate was measured by stathmokinetic techniques. Scanning electron microscopy showed microadenomas as early as five weeks and consistently after 15 weeks. They were found predominantly in the distal colon and increased in size with time. The lesions showed a progressive increase in the number of crypts per adenoma and increasingly disorganised slit shaped crypt orifices. The presence of epithelial dysplasia in the microadenomas and of invasion of the colonic wall by carcinoma was confirmed histologically, although fewer lesions were identified in tissue sections than by scanning electron microscopy. Crypt cell production rate increased with time, particularly in the distal colon. This increase was significant between five and 25 weeks. The results of these observations suggest that there is an adenoma-carcinoma sequence in this animal model. The value of scanning electron microscopy in identifying and quantifying the mucosal changes during carcinogenesis is emphasised." @default.
• W2155178437 created "2016-06-24" @default.
• W2155178437 creator A5019279731 @default.
• W2155178437 creator A5038480423 @default.
• W2155178437 creator A5054274883 @default.
• W2155178437 creator A5064478582 @default.
• W2155178437 creator A5073462682 @default.
• W2155178437 creator A5081137447 @default.
• W2155178437 date "1984-07-01" @default.
• W2155178437 modified "2023-09-27" @default.
• W2155178437 title "Detection of early neoplastic changes in experimentally induced colorectal cancer using scanning electron microscopy and cell kinetic studies." @default.
• W2155178437 cites W1665644534 @default.
• W2155178437 cites W192836935 @default.
• W2155178437 cites W1934171949 @default.
• W2155178437 cites W1974885258 @default.
• W2155178437 cites W1983167684 @default.
• W2155178437 cites W1994404498 @default.
• W2155178437 cites W2001772038 @default.
• W2155178437 cites W2021401748 @default.
• W2155178437 cites W2028649875 @default.
• W2155178437 cites W2043869692 @default.
• W2155178437 cites W2063619364 @default.
• W2155178437 cites W2070603890 @default.
• W2155178437 cites W2094049289 @default.
• W2155178437 cites W2132785209 @default.
• W2155178437 cites W2136079026 @default.
• W2155178437 cites W2172465900 @default.
• W2155178437 cites W2283057446 @default.
• W2155178437 cites W2299171734 @default.
• W2155178437 cites W2408126529 @default.
• W2155178437 cites W2471312303 @default.
• W2155178437 cites W258982941 @default.
• W2155178437 doi "https://doi.org/10.1136/gut.25.7.748" @default.
• W2155178437 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1432594" @default.
• W2155178437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6735256" @default.
• W2155178437 hasPublicationYear "1984" @default.
• W2155178437 type Work @default.
• W2155178437 sameAs 2155178437 @default.
• W2155178437 citedByCount "34" @default.
• W2155178437 countsByYear W21551784372012 @default.
• W2155178437 countsByYear W21551784372014 @default.
• W2155178437 countsByYear W21551784372015 @default.
• W2155178437 countsByYear W21551784372016 @default.
• W2155178437 countsByYear W21551784372018 @default.
• W2155178437 countsByYear W21551784372019 @default.
• W2155178437 crossrefType "journal-article" @default.
• W2155178437 hasAuthorship W2155178437A5019279731 @default.
• W2155178437 hasAuthorship W2155178437A5038480423 @default.
• W2155178437 hasAuthorship W2155178437A5054274883 @default.
• W2155178437 hasAuthorship W2155178437A5064478582 @default.
• W2155178437 hasAuthorship W2155178437A5073462682 @default.
• W2155178437 hasAuthorship W2155178437A5081137447 @default.
• W2155178437 hasBestOaLocation W21551784371 @default.
• W2155178437 hasConcept C120665830 @default.
• W2155178437 hasConcept C121332964 @default.
• W2155178437 hasConcept C121608353 @default.
• W2155178437 hasConcept C126322002 @default.
• W2155178437 hasConcept C142724271 @default.
• W2155178437 hasConcept C159985019 @default.
• W2155178437 hasConcept C192562407 @default.
• W2155178437 hasConcept C26771246 @default.
• W2155178437 hasConcept C2775894508 @default.
• W2155178437 hasConcept C2777428134 @default.
• W2155178437 hasConcept C2778452354 @default.
• W2155178437 hasConcept C2780669762 @default.
• W2155178437 hasConcept C3018440083 @default.
• W2155178437 hasConcept C526805850 @default.
• W2155178437 hasConcept C66090201 @default.
• W2155178437 hasConcept C71924100 @default.
• W2155178437 hasConcept C86803240 @default.
• W2155178437 hasConcept C93877712 @default.
• W2155178437 hasConceptScore W2155178437C120665830 @default.
• W2155178437 hasConceptScore W2155178437C121332964 @default.
• W2155178437 hasConceptScore W2155178437C121608353 @default.
• W2155178437 hasConceptScore W2155178437C126322002 @default.
• W2155178437 hasConceptScore W2155178437C142724271 @default.
• W2155178437 hasConceptScore W2155178437C159985019 @default.
• W2155178437 hasConceptScore W2155178437C192562407 @default.
• W2155178437 hasConceptScore W2155178437C26771246 @default.
• W2155178437 hasConceptScore W2155178437C2775894508 @default.
• W2155178437 hasConceptScore W2155178437C2777428134 @default.
• W2155178437 hasConceptScore W2155178437C2778452354 @default.
• W2155178437 hasConceptScore W2155178437C2780669762 @default.
• W2155178437 hasConceptScore W2155178437C3018440083 @default.
• W2155178437 hasConceptScore W2155178437C526805850 @default.
• W2155178437 hasConceptScore W2155178437C66090201 @default.
• W2155178437 hasConceptScore W2155178437C71924100 @default.
• W2155178437 hasConceptScore W2155178437C86803240 @default.
• W2155178437 hasConceptScore W2155178437C93877712 @default.
• W2155178437 hasIssue "7" @default.
• W2155178437 hasLocation W21551784371 @default.
• W2155178437 hasLocation W21551784372 @default.
• W2155178437 hasLocation W21551784373 @default.
• W2155178437 hasLocation W21551784374 @default.
• W2155178437 hasOpenAccess W2155178437 @default.
• W2155178437 hasPrimaryLocation W21551784371 @default.
• W2155178437 hasRelatedWork W1757947864 @default.
• W2155178437 hasRelatedWork W1907210134 @default.

• next