FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155227562> ?p ?o ?g. }

• W2155227562 endingPage "753" @default.
• W2155227562 startingPage "745" @default.
• W2155227562 abstract "To compare the proportion of patients who prefer rizatriptan orally disintegrating tablet (ODT) 10-mg to sumatriptan 50-mg tablet.Migraineurs express treatment preference based on a variety of attributes including the speed of pain relief and medication formulation. Rizatriptan ODT is an orally disintegrating formulation of rizatriptan, a selective 5-HT1B/1D receptor agonist. This study was conducted to determine patient preference between rizatriptan ODT 10-mg and sumatriptan 50-mg tablet for the acute treatment of migraine.This was a multicenter, randomized, open-label, two-period crossover study conducted in the United States with 524 enrolled patients. Patients treated a single moderate or severe headache in each treatment period. Patients treated one migraine with either rizatriptan ODT 10-mg or sumatriptan 50-mg tablet, then treated a second migraine with the alternate therapy. Patients completed diary assessments at baseline, and 30, 45, 60, 90, and 120 minutes postdose and rated headache severity on a 4-point scale (0 = none, 1 = mild, 2 = moderate, and 3 = severe). At the final study visit following treatment of their second migraine, patients expressed preference for one of the two study medications by completing an interviewer-administered Global Preference Question and then responded to a self-administered series of questions to capture their most important reason for preferring one study medication over the other. Safety measurements were recorded through standard adverse experience reporting.Three hundred eighty-six patients treated two migraine attacks. For those patients who expressed a preference for either rizatriptan ODT or sumatriptan (n = 374), the percentage of patients who preferred rizatriptan ODT 10-mg (57%, n = 213) was significantly greater than those who preferred sumatriptan 50-mg tablet (43%, n = 161) (P<.01). For those patients who treated two migraine attacks and had drug severity measures for both attacks (n = 384), a significantly greater percentage of patients reported pain relief after taking rizatriptan ODT than sumatriptan at the 45- and 60-minute time points (38% versus 29% and 58% versus 49%, respectively) (P<.01). In addition, a significantly greater percentage of patients taking rizatriptan ODT reported a pain-free status at the 60- and 120-minute time points (23% versus 17% [P<.05] and 60% versus 52% [P<.01], respectively). Both rizatriptan ODT and sumatriptan were well tolerated.A significantly greater proportion of patients preferred rizatriptan ODT 10-mg to sumatriptan 50-mg tablet for the acute treatment of migraine. Efficacy and safety data are consistent with the preference findings." @default.
• W2155227562 created "2016-06-24" @default.
• W2155227562 creator A5002602878 @default.
• W2155227562 creator A5021476107 @default.
• W2155227562 creator A5023730853 @default.
• W2155227562 creator A5036640479 @default.
• W2155227562 creator A5046741448 @default.
• W2155227562 creator A5054045289 @default.
• W2155227562 creator A5060701773 @default.
• W2155227562 creator A5063243006 @default.
• W2155227562 creator A5066559208 @default.
• W2155227562 creator A5077491495 @default.
• W2155227562 creator A5079689324 @default.
• W2155227562 date "2001-09-04" @default.
• W2155227562 modified "2023-09-25" @default.
• W2155227562 title "Preference Comparison of Rizatriptan ODT 10-mg and Sumatriptan 50-mg Tablet in Migraine" @default.
• W2155227562 cites W2026813826 @default.
• W2155227562 cites W2048461020 @default.
• W2155227562 cites W2099275034 @default.
• W2155227562 cites W2114413295 @default.
• W2155227562 cites W4300429268 @default.
• W2155227562 doi "https://doi.org/10.1046/j.1526-4610.2001.01138.x" @default.
• W2155227562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11576197" @default.
• W2155227562 hasPublicationYear "2001" @default.
• W2155227562 type Work @default.
• W2155227562 sameAs 2155227562 @default.
• W2155227562 citedByCount "47" @default.
• W2155227562 countsByYear W21552275622012 @default.
• W2155227562 countsByYear W21552275622016 @default.
• W2155227562 countsByYear W21552275622017 @default.
• W2155227562 countsByYear W21552275622022 @default.
• W2155227562 crossrefType "journal-article" @default.
• W2155227562 hasAuthorship W2155227562A5002602878 @default.
• W2155227562 hasAuthorship W2155227562A5021476107 @default.
• W2155227562 hasAuthorship W2155227562A5023730853 @default.
• W2155227562 hasAuthorship W2155227562A5036640479 @default.
• W2155227562 hasAuthorship W2155227562A5046741448 @default.
• W2155227562 hasAuthorship W2155227562A5054045289 @default.
• W2155227562 hasAuthorship W2155227562A5060701773 @default.
• W2155227562 hasAuthorship W2155227562A5063243006 @default.
• W2155227562 hasAuthorship W2155227562A5066559208 @default.
• W2155227562 hasAuthorship W2155227562A5077491495 @default.
• W2155227562 hasAuthorship W2155227562A5079689324 @default.
• W2155227562 hasConcept C126322002 @default.
• W2155227562 hasConcept C142724271 @default.
• W2155227562 hasConcept C168563851 @default.
• W2155227562 hasConcept C170493617 @default.
• W2155227562 hasConcept C197934379 @default.
• W2155227562 hasConcept C204787440 @default.
• W2155227562 hasConcept C27081682 @default.
• W2155227562 hasConcept C2777030092 @default.
• W2155227562 hasConcept C2778541695 @default.
• W2155227562 hasConcept C2778871607 @default.
• W2155227562 hasConcept C2778938600 @default.
• W2155227562 hasConcept C42219234 @default.
• W2155227562 hasConcept C71924100 @default.
• W2155227562 hasConcept C87813604 @default.
• W2155227562 hasConceptScore W2155227562C126322002 @default.
• W2155227562 hasConceptScore W2155227562C142724271 @default.
• W2155227562 hasConceptScore W2155227562C168563851 @default.
• W2155227562 hasConceptScore W2155227562C170493617 @default.
• W2155227562 hasConceptScore W2155227562C197934379 @default.
• W2155227562 hasConceptScore W2155227562C204787440 @default.
• W2155227562 hasConceptScore W2155227562C27081682 @default.
• W2155227562 hasConceptScore W2155227562C2777030092 @default.
• W2155227562 hasConceptScore W2155227562C2778541695 @default.
• W2155227562 hasConceptScore W2155227562C2778871607 @default.
• W2155227562 hasConceptScore W2155227562C2778938600 @default.
• W2155227562 hasConceptScore W2155227562C42219234 @default.
• W2155227562 hasConceptScore W2155227562C71924100 @default.
• W2155227562 hasConceptScore W2155227562C87813604 @default.
• W2155227562 hasIssue "8" @default.
• W2155227562 hasLocation W21552275621 @default.
• W2155227562 hasLocation W21552275622 @default.
• W2155227562 hasOpenAccess W2155227562 @default.
• W2155227562 hasPrimaryLocation W21552275621 @default.
• W2155227562 hasRelatedWork W1797331005 @default.
• W2155227562 hasRelatedWork W1981530708 @default.
• W2155227562 hasRelatedWork W1984045891 @default.
• W2155227562 hasRelatedWork W2016988616 @default.
• W2155227562 hasRelatedWork W2039623332 @default.
• W2155227562 hasRelatedWork W2119553926 @default.
• W2155227562 hasRelatedWork W2128656142 @default.
• W2155227562 hasRelatedWork W2155227562 @default.
• W2155227562 hasRelatedWork W2170714231 @default.
• W2155227562 hasRelatedWork W2319483612 @default.
• W2155227562 hasVolume "41" @default.
• W2155227562 isParatext "false" @default.
• W2155227562 isRetracted "false" @default.
• W2155227562 magId "2155227562" @default.
• W2155227562 workType "article" @default.